Proteomic characterization of harvested pseudopodia with differential gel electrophoresis and specific antibodies

Cell Migration: Integrating Signals from Front to Back

2003 • 4,755 citations

Difference gel electrophoresis. A single gel method for detecting changes in protein extracts

1997 • 2,181 citations

The role of glutathione-S-transferase in anti-cancer drug resistance

2003 • 1,253 citations

Reconstitution of actin-based motility of Listeria and Shigella using pure proteins

1999 • 968 citations

New insights into an old protein: the functional diversity of mammalian glyceraldehyde-3-phosphate dehydrogenase

1999 • 803 citations

Annexins – unique membrane binding proteins with diverse functions

2004 • 574 citations

Morphological and biochemical characterization and analysis of apoptosis

1997 • 478 citations

Actin Polymerization and ATP Hydrolysis

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Prolyl 4-hydroxylases, the key enzymes of collagen biosynthesis

2003 • 431 citations

Met and hepatocyte growth factor/scatter factor expression in human gliomas.

1997 • 324 citations

Altered Hsp90 function in cancer: A unique therapeutic opportunity

2004 • 305 citations

Levels of vascular endothelial growth factor, hepatocyte growth factor/scatter factor and basic fibroblast growth factor in human gliomas and their relation to angiogenesis

1999 • 296 citations

Combinatorial attack on multistep oncogenesis by inhibiting the Hsp90 molecular chaperone

2003 • 243 citations

Pericellular cathepsin B and malignant progression.

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Peripheral astrocyte processes: Monitoring by selective immunostaining for the actin‐binding ERM proteins

2001 • 191 citations

Ubiquitin carboxyl-terminal hydrolase acts on ubiquitin carboxyl-terminal amides.

1985 • 187 citations

Reversion of Human Glioblastoma Malignancy by U1 Small Nuclear RNA/Ribozyme Targeting of Scatter Factor/Hepatocyte Growth Factor and c-met Expression

1999 • 181 citations

Identification and validation of metastasis-associated proteins in head and neck cancer cell lines by two-dimensional electrophoresis and mass spectrometry.

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Interactions between glycolytic enzymes and components of the cytomatrix.

1984 • 171 citations

Anomalous expression of the HLA-DR alpha and beta chains in ovarian and other cancers

2004 • 165 citations

Molecular Classification and Survival Prediction in Human Gliomas Based on Proteome Analysis

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Glycolytic enzyme interactions with tubulin and microtubules

1989 • 149 citations

VCP (p97) Regulates NFKB Signaling Pathway, Which Is Important for Metastasis of Osteosarcoma Cell Line

2002 • 143 citations

Glycolysis as Primary Energy Source in Tumor Cell Chemotaxis

1990 • 129 citations

Glioblastoma and Cerebral Microvascular Endothelial Cell Migration in Response to Tumor-associated Growth Factors

2003 • 125 citations

Specific interaction of tissue-type plasminogen activator (t-PA) with annexin II on the membrane of pancreatic cancer cells activates plasminogen and promotes invasion in vitro

2004 • 122 citations

Enhanced expression of the protein kinase substrate annexin in human hepatocellular carcinoma

1996 • 121 citations

Scatter factor promotes motility of human glioma and neuromicrovascular endothelial cells

1998 • 119 citations

Differential expression of annexin I in human mammary ductal epithelial cells in normal and benign and malignant breast tissues.

1997 • 112 citations

Elevated Expression of Valosin-Containing Protein (p97) Is Associated with Poor Prognosis of Prostate Cancer

2004 • 109 citations

Interaction of muscle glycolytic enzymes with thin filament proteins

1981 • 108 citations

Elevated expression of valosin-containing protein (p97) in hepatocellular carcinoma is correlated with increased incidence of tumor recurrence

2004 • 108 citations

Scatter factor/hepatocyte growth factor (SF/HGF) content and function in human gliomas

1999 • 102 citations

Gliomas are driven by glycolysis: putative roles of hexokinase, oxidative phosphorylation and mitochondrial ultrastructure.

1997 • 99 citations

Increased expression of annexin I and thioredoxin detected by two-dimensional gel electrophoresis of drug resistant human stomach cancer cells

1998 • 96 citations

Down‐regulation of microglial cyclo‐oxygenase‐2 and inducible nitric oxide synthase expression by lipocortin 1

1999 • 94 citations

Expression Level of Valosin-Containing Protein Is Strongly Associated With Progression and Prognosis of Gastric Carcinoma

2003 • 88 citations

Hormone-refractory breast cancer remains sensitive to the antitumor activity of heat shock protein 90 inhibitors.

2003 • 83 citations

The Hepatocyte Growth Factor Receptor Kinase-mediated Phosphorylation of Lipocortin-1 Transduces the Proliferating Signal of the Hepatocyte Growth Factor

1996 • 81 citations

Hsp90 inhibitors deplete key anti‐apoptotic proteins in pediatric solid tumor cells and demonstrate synergistic anticancer activity with cisplatin

2004 • 81 citations

A Glycolytic Enzyme Binding Domain on Tubulin

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Annexin II and Regulation of Cell Surface Fibrinolysis

2000 • 75 citations

Microtubules bind glyceraldehyde 3-phosphate dehydrogenase and modulate its enzyme activity and quaternary structure

1987 • 75 citations

Antigenic probes locate binding sites for the glycolytic enzymes glyceraldehyde-3-phosphate dehydrogenase, aldolase and phosphofructokinase on the actin monomer in microfilaments

1989 • 74 citations

Expression of Valosin-Containing Protein in Colorectal Carcinomas as a Predictor for Disease Recurrence and Prognosis

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Microcompartmentation of glycolytic enzymes in cultured cells.

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Proteomics in pathology research

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A nonapeptide to the putative F-actin binding site of annexin-II tetramer inhibits its calcium-dependent activation of actin filament bundling.

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Glycolytic enzymes and assembly of microtubule networks

1995 • 67 citations

Human recombinant lipocortin 1 inhibits prostacyclin production by human umbilical artery

1987 • 66 citations

Heteromerous interactions among glycolytic enzymes and of glycolytic enzymes with F-actin: effects of poly(ethylene glycol)

1988 • 66 citations

Increased Expression of Valosin-Containing Protein (p97) is Associated With Lymph Node Metastasis and Prognosis of Pancreatic Ductal Adenocarcinoma

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The hydrolysis of ATP that accompanies actin polymerization is essentially irreversible

1988 • 64 citations

Annexin II marks astrocytic brain tumors of high histologic grade.

1994 • 61 citations

Expression Level of Valosin-Containing Protein (p97) Is Correlated With Progression and Prognosis of Non-Small-Cell Lung Carcinoma

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Expression Level of Valosin-Containing Protein (p97) Is Associated with Prognosis of Esophageal Carcinoma

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Actin-based motility as a self-organized system: mechanism and reconstitution in vitro

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Evolution of a dynamic cytoskeleton

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Analysis of the binding of glyceraldehyde‐3‐phosphate dehydrogenase to microtubules, the mechanism of bundle formation and the linkage effect

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Purification and Characterization of β-Actin-Rich Tumor Cell Pseudopodia: Role of Glycolysis

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Elevated levels of annexin I protein in vitro and in vivo in rat and human mammary adenocarcinoma.

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Lipocortin-1 immunoreactivity in central and peripheral nervous system glial tumors

1989 • 50 citations

Increased beta-actin expression in an invasive moloney sarcoma virus-transformed MDCK cell variant concentrates to the tips of multiple pseudopodia.

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Identification of metastasis-associated proteins through protein analysis of metastatic MDA-MB-435 and metastasis-suppressed BRMS1 transfected-MDA-MB-435 cells

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Binding of glyceraldehyde 3-phosphate dehydrogenase to microtubules

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Two Phases of Pseudopod Protrusion in Tumor Cells Revealed by a Micropipette

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Demonstration of tubulin-glycolytic enzyme interactions using a novel electrophoretic approach

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Expression level of valosin-containing protein (VCP) as a prognostic marker for gingival squamous cell carcinoma

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HGF/SF Activates Glycolysis and Oxidative Phosphorylation in DA3 Murine Mammary Cancer Cells

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Glial cell expression of hepatocyte growth factor in vitreoretinal proliferative disease

2004 • 29 citations

Glucocorticoid induced the expression of mRNA and the secretion of lipocortin 1 in rat astrocytoma cells

1997 • 27 citations

Astroglial expression of hepatocyte growth factor and hepatocyte growth factor activator in human brain tissues

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Changes in the cellular distribution of Lipocortin-1 (Annexin-1) in C6 glioma cells after exposure to dexamethasone

1995 • 25 citations

Association of glycolytic enzymes with the cytoplasmic side of the plasma membrane of glioma cells

1988 • 25 citations

Hepatocyte growth factor (HGF) and receptor (c-met) in normal and malignant astrocytic cells.

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Glycolytic enzyme–tubulin interactions: Role of tubulin carboxy terminals

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How profilin/barbed-end synergy controls actin polymerization: A kinetic model of the ATP hydrolysis circuit

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Membrane-Specific Association of Annexin I and Annexin II in Anterior Pituitary Cells*

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Nucleotide hydrolysis regulates the dynamics of actin filaments and microtubules

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Expression of hepatocyte growth factor and matrix metalloproteinase-2 in human glioma

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