Detection of activity of P‐glycoprotein in human tumour samples using rhodamine 123

Proposals for the Classification of the Acute Leukaemias F<scp>rench</scp>‐A<scp>merican</scp>‐B<scp>ritish</scp> (FAB) C<scp>o‐operative</scp> G<scp>roup</scp>

1976 • 5,620 citations

Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells

1991 • 962 citations

Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction.

1990 • 736 citations

Multiple-Drug Resistance in Human Cancer

1987 • 703 citations

Drug-resistance in multiple myeloma and non-Hodgkin's lymphoma: detection of P-glycoprotein and potential circumvention by addition of verapamil to chemotherapy.

1989 • 565 citations

Functional role for the 170- to 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies.

1986 • 561 citations

P-glycoprotein expression in malignant lymphoma and reversal of clinical drug resistance with chemotherapy plus high-dose verapamil.

1991 • 388 citations

MDR1 Gene Expression and Treatment Outcome in Acute Myeloid Leukemia

1991 • 372 citations

Flow cytometric analysis of human bone marrow: I. Normal erythroid development

1987 • 353 citations

Use of fluorescent dyes as molecular probes for the study of multidrug resistance

1988 • 249 citations

Multidrug-resistant myeloma: laboratory and clinical effects of verapamil as a chemosensitizer

1991 • 228 citations

Expression of mdr1 and mdr3 Multidrug-resistance Genes in Human Acute and Chronic Leukemias and Association With Stimulation of Drug Accumulation by Cyclosporine

1990 • 210 citations

P-glycoproteins in pathology: The multidrug resistance gene family in humans

1990 • 173 citations

Multidrug Resistance

1989 • 166 citations

Surface marker expression in adult acute myeloid leukaemia: correlations with initial characteristics, morphology and response to therapy

1989 • 147 citations

Multidrug Resistance: Molecular Biology Clinical Relevance

1989 • 114 citations

Multidrug resistance activity in human lymphocytes

1991 • 100 citations

Immunohistochemical detection of multidrug resistance associated P-glycoprotein in tumour and stromal cells of human cancers

1990 • 96 citations

Reciprocal correlation between expression of P-glycoprotein and accumulation of rhodamine 123 in human tumors.

1989 • 79 citations

Laser scanning and confocal microscopy of daunorubicin, doxorubicin, and rhodamine 123 in multidrug-resistant cells

1991 • 79 citations

Multidrug Resistance: P-glycoprotein and Its Allies--The Elusive Foes

1989 • 61 citations

The Clinical Relevance of Multidrug Resistance

1990 • 55 citations

Expression of the multiple drug resistance gene (mdr‐1) and epitope masking in chronic lymphatic leukaemia

1990 • 53 citations

Reversal of multidrug resistance by B859-35, a metabolite of B859-35, niguldipine, verapamil and nitrendipine

1992 • 51 citations

Multidrug resistance from the clinical point of view

1991 • 47 citations

Simultaneous use of Rhodamine 123, phycoerythrin, Texas red, and allophycocyanin for the isolation of human hematopoietic progenitor cells

1991 • 45 citations

A rapid and sensitive flow cytometric method for the detection of multidrug‐resistant cells

1989 • 39 citations

Flow cytometric double labeling technique for screening of multidrug resistance

1991 • 38 citations

Rapid functional assay for the detection of multidrug-resistant cells using the fluorescent dye rhodamine 123 [letter; comment]

1991 • 34 citations

B‐859‐35, a new drug with anti‐tumor activity reverses multi‐drug resistance

1991 • 26 citations

Rapid Functional Assay for Multidrug Resistance in Human Tumor Cell Lines Using the Fluorescent Indicator Fluo-3

1991 • 25 citations

Hairy cell leukemia: splenectomy after alpha 2b-interferon therapy [letter] [see comments]

1991 • 24 citations

AACR Special Conference In Cancer Research Membrane transport in multidrug resistance, development, and disease

1991 • 11 citations