1986: A year of new insights into how proteins cross membranes

Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.

1975 • 3,026 citations

Binding of a specific ligand inhibits import of a purified precursor protein into mitochondria

1986 • 723 citations

Multiple Mechanisms of Protein Insertion into and Across Membranes

1985 • 720 citations

Correlation of competence for export with lack of tertiary structure of the mature species: A study in vivo of maltose-binding protein in E. coli

1986 • 473 citations

Transport of proteins into mitochondria: Translocational intermediates spanning contact sites between outer and inner membranes

1985 • 470 citations

In vitro protein translocation across the yeast endoplasmic reticulum: ATP-dependent post-translational translocation of the prepro-α-factor

1986 • 332 citations

Secretory protein translocation in a yeast cell-free system can occur posttranslationally and requires ATP hydrolysis.

1986 • 315 citations

Effects of two sec genes on protein assembly into the plasma membrane of Escherichia coli.

1985 • 217 citations

Secretion in yeast: Reconstitution of the translocation and glycosylation of α-factor and invertase in a homologous cell-free system

1986 • 216 citations

Uncoupling Translocation from Translation: Implications for Transport of Proteins Across Membranes

1986 • 195 citations

Secretion in yeast: translocation and glycosylation of prepro-α-factor in vitro can occur via an ATP-dependent post-translational mechanism

1986 • 185 citations

Elongation arrest is not a prerequisite for secretory protein translocation across the microsomal membrane.

1985 • 179 citations

Removal of the Alu structural domain from signal recognition particle leaves its protein translocation activity intact

1986 • 176 citations

Cell biology: An unfolding story of protein translocation

1986 • 126 citations

The cytoplasmic carboxy terminus of M13 procoat is required for the membrane insertion of its central domain

1986 • 92 citations

Post-translational insertion of fragment of the glucose transporter into microsomes requires phosphoanhydride bond cleavage

1986 • 75 citations

Signal recognition particle (SRP) does not mediate a translational arrest of nascent secretory proteins in mammalian cell-free systems.

1985 • 73 citations

Import of honeybee prepromelittin into the endoplasmic reticulum. Requirements for membrane insertion, processing, and sequestration.

1986 • 71 citations

Translocation of nascent secretory proteins across membranes can occur late in translation.

1986 • 62 citations

Transfer of Secretory Proteins through the Membrane of the Endoplasmic Reticulum

1986 • 58 citations

Genetic Studies on Protein Export in Bacteria

1986 • 45 citations

M13 coat protein as a model of membrane assembly

1983 • 33 citations

Demonstration of post-translational secretion of human placental lactogen by a mammalian in vitro translation system.

1986 • 32 citations

Protein translocation: A common mechanism for different membrane systems?

1986 • 31 citations

Protein compartmentalization

1987 • 21 citations

Genetic control of protein secretion and localization

1986 • 11 citations