Cholecystokinin B receptor antagonists enhance the locomotor response to the N-methyl-d-aspartate antagonists phencyclidine and dizocilpine maleate

Recent advances in the phencyclidine model of schizophrenia

1991 • 2,886 citations

Interactions between glutamatergic and monoaminergic systems within the basal ganglia-implications for schizophrenia and Parkinson's disease

1990 • 1,102 citations

Study of a New Schizophrenomimetic Drug—Sernyl

1959 • 922 citations

Organization of the projections from the subiculum to the ventral striatum in the rat. A study using anterograde transport of Phaseolus vulgaris leucoagglutinin

1987 • 857 citations

New peptide in the vertebrate CNS reacting with antigastrin antibodies

1975 • 749 citations

Two brain cholecystokinin receptors: implications for behavioral actions

1986 • 719 citations

A subpopulation of mesencephalic dopamine neurons projecting to limbic areas contains a cholecystokinin-like peptide: Evidence from immunohistochemistry combined with retrograde tracing

1980 • 717 citations

Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia

1980 • 703 citations

DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. III. Immunocytochemical localization

1984 • 652 citations

Amino acid neurotransmitters and their pathways in the mammalian central nervous system

1983 • 646 citations

DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1

1984 • 610 citations

Distinct cholecystokinin receptors in brain and pancreas.

1980 • 574 citations

Amphetamine, cocaine, phencyclidine and nomifensine increase extracellular dopamine concentrations preferentially in the nucleus accumbens of freely moving rats

1989 • 562 citations

Coexistence of peptides and classical neurotransmitters

1983 • 559 citations

Biochemical evidence for glutamate as neurotransmitter in corticostriatal and corticothalamic fibres in rat brain

1981 • 547 citations

The distribution of cholecystokinin immunoreactivity in the central nervous system of the rat as determined by radioimmunoassay

1981 • 545 citations

Development of a class of selective cholecystokinin type B receptor antagonists having potent anxiolytic activity.

1990 • 501 citations

Anticonvulsant activity of (+)‐5‐methyl‐10, 11‐dihydro‐5H‐dibenzo[a, d]cyclohepten‐5, 10‐imine (MK‐801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties

1982 • 496 citations

A glutamatergic corticostriatal path?

1977 • 487 citations

A new potent and selective non-peptide gastrin antagonist and brain cholecystokinin receptor (CCK-B) ligand: L-365,260

1989 • 404 citations

Activation of NMDA receptors induces dephosphorylation of DARPP-32 in rat striatal slices

1990 • 356 citations

Effect of frontal cortex ablation on striatal glutamic acid level in rat

1977 • 306 citations

Benzodiazepine gastrin and brain cholecystokinin receptor ligands; L-365,260

1989 • 304 citations

Cholecystokinin receptors

1995 • 299 citations

A “Glutamatergic Hypothesis” of Schizophrenia

1989 • 270 citations

Behavioral rating scales for assessing phencyclidine-induced locomotor activity, stereotypes behavior and ataxia in rats

1979 • 236 citations

Cholecystokinins in rat cerebral cortex: Identification, purification and characterization by immunochemical methods

1980 • 232 citations

Central sympathomimetic activity of (+)‐5‐methyl‐10,11‐dihydro‐5H‐dibenzo [a, d]cyclohepten‐5,10‐imine (MK‐801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties

1982 • 229 citations

Sites for Antagonism on the N-Methyl-D-Aspartate Receptor Channel Complex

1991 • 216 citations

The effects of phencyclidine and N-allylnormetazocine on midbrain dopamine neuronal activity

1984 • 181 citations

Glutamate release in vitro from corticostriatal terminals

1979 • 179 citations

Phencyclidine and related drugs bind to the activated receptor-channel complex in rat brain membranes

1987 • 170 citations

Cholecystokinin potentiates dopamine-mediated behaviors: evidence for modulation specific to a site of coexistence

1985 • 166 citations

Cholecystokinin potentiates dopamine-mediated behaviors: evidence for modulation specific to a site of coexistence.

1985 • 165 citations

Neuropharmacology of Phencyclidine: Basic Mechanisms and Therapeutic Potential

1990 • 160 citations

Non-competitive antagonists are potent activators of ventral tegmental A10 dopamine neurons

1990 • 157 citations

An Excitant Amino Acid Projection from the Medial Prefrontal Cortex to the Anterior Part of Nucleus Accumbens in the Rat

1985 • 151 citations

Cholecystokinin Modulates the Release of Dopamine from the Anterior and Posterior Nucleus Accumbens by Two Different Mechanisms

1991 • 150 citations

Biochemical investigation on the localization of the cholecystokinin octapeptide in dopaminergic neurons originating from the ventral tegmental area of the rat

1981 • 140 citations

Ventral mesencephalic neurons containing both cholecystokinin‐ and tyrosine hydroxylase‐like immunoreactivities project to forebrain regions

1989 • 139 citations

Interactions of cholecystokinin octapeptide and dopamine on nucleus accumbens neurons

1984 • 137 citations

Mesolimbic and mesocortical dopamine activation induced by phencyclidine: contrasting pattern to striatal response

1987 • 133 citations

Origin of the Cholecystokinin-Containing Fibers in the Rat Caudatoputamen

1982 • 132 citations

In vivo biosynthesis of cholecystokinin in rat cerebral cortex.

1980 • 130 citations

Cholecystokinin and tyrosine hydroxylase messenger RNAs in neurons of rat mesencephalon: peptide/monoamine coexistence studies using in situ hybridization combined with immunocytochemistry

1989 • 126 citations

Effect of phenycyclidine on dopamine release in the rat prefrontal cortex; an in vivo microdialysis study

1994 • 120 citations

Phencyclidine- and Dizocilpine-Induced Hyperlocomotion Are Differentially Mediated

1994 • 113 citations

Topographical analysis of nucleus accumbens sites at which cholecystokinin potentiates dopamine-induced hyperlocomotion in the rat

1985 • 97 citations

Subtype-selective cholecystokinin receptor antagonists block cholecystokinin modulation of dopamine-mediated behaviors in the rat mesolimbic pathway

1992 • 94 citations

A projection from the entorhinal cortex to the nucleus accumbens in the rat

1981 • 90 citations

Cholecystokinin in Cortico‐striatal Neurons in the Rat: Immunohistochemical Studies at the Light and Electron Microscopical Level

1994 • 90 citations

Nucleus accumbens cholecystokinin (CCK) can either attenuate or potentiate amphetamine-induced locomotor activity: Evidence for rostral-caudal differences in accumbens CCK function.

1989 • 88 citations

Cholecystokinins in the central nervous system and neurohypophysis

1981 • 88 citations

Stereotyped behavior correlates better than ataxia with phencyclidine-receptor interactions

1986 • 79 citations

Differential effects of acute and chronic administration of haloperidol on homovanillic acid levels in discrete dopaminergic areas of rat brain

1983 • 78 citations

Nucleus accumbens dopamine-CCK interactions in psychostimulant reward and related behaviors

1994 • 77 citations

Nucleus accumbens cholecystokinin (CCK) can either attenuate or potentiate amphetamine-induced locomotor activity: Evidence for rostral-caudal differences in accumbens CCK function.

1989 • 75 citations

Selective activation of dopaminergic pathways in the mesocortex by compounds that act at the phencyclidine (pcp) binding site: tentative evidence for pcp recognition sites not coupled to n-methyl-d-aspartate (nmda) receptors

1990 • 71 citations

Phencyclidine-induced locomotor activity in the rat is blocked by 6-hydroxydopamine lesion of the nucleus accumbens: Comparisons to other psychomotor stimulants

1983 • 68 citations

Effect of 6-hydroxydopamine lesions of the medial forebrain bundle on the distribution of cholecystokinin in rat forebrain

1982 • 68 citations

Effects of phencyclidine on ventral tegmental A10 dopamine neurons in the rat

1986 • 68 citations

Pharmacological study on the mixed CCK8/DA meso-nucleus accumbens pathway: Evidence for the existence of storage sites containing the two transmitters

1984 • 66 citations

Phencyclidine binding sites in the nucleus accumbens and phencyclidine-induced hyperactivity are decreased following lesions of the mesolimbic dopamine system

1985 • 65 citations

CCK nerve terminals in the rat striatal and limbic areas originate partly in the brain stem and partly in telencephalic structures

1983 • 63 citations

High-Affinity and Potent, Water-Soluble 5-Amino-1,4-benzodiazepine CCKB/Gastrin Receptor Antagonists Containing a Cationic Solubilizing Group

1994 • 61 citations

On the Origin of Striatal Cholecystokinin Release: Studies with In Vivo Microdialysis

1994 • 61 citations

Electrophysiological effects of diphenylpyrazolidinone cholecystokinin-B and cholecystokinin-A antagonists on midbrain dopamine neurons.

1993 • 55 citations

Brain CCK-B receptors mediate the suppression of dopamine release by cholecystokinin

1989 • 53 citations

Pharmacological and mechanistic studies of cholecystokinin-facilitated [3H]dopamine efflux from rat nucleus accumbens

1989 • 50 citations

Changes in brain cholecystokinin octapeptide following lesions of the medial forebrain bundle

1981 • 49 citations

Second-Generation Benzodiazepine CCK-B Antagonists. Development of Subnanomolar Analogs with Selectivity and Water Solubility

1994 • 45 citations

Phencyclidine increases extracellular dopamine metabolites in rat medial frontal cortex as measured by in vivo dialysis

1990 • 44 citations

Antagonism of cholecystokinin function in the rostral and caudal nucleus accumbens: Differential effects on brain stimulation reward

1989 • 42 citations

The transfer of rats from a familiar to a novel environment prolongs the increase of extracellular dopamine efflux induced by CCK8 in the posterior nucleus accumbens

1995 • 41 citations

A comparison of the effects of neuroleptics on phencyclidine-induced behaviors in the rat

1981 • 40 citations

Biological properties of the benzodiazepine amidine derivative L-740,093, a cholecystokinin-B/gastrin receptor antagonist with high affinity in vitro and high potency in vivo.

1994 • 39 citations

Opposite actions of CCK-8 on amphetamine-induced hyperlocomotion and stereotypy following intracerebroventricular and intra-accumbens injections in rats

1988 • 39 citations

Cholecystokinin corticostriatal pathway in the rat: Evidence for bilateral origin from medial prefrontal cortical areas

1994 • 38 citations

Regulation by the neuropeptide cholecystokinin (CCK-8S) of protein phosphorylation in the neostriatum.

1993 • 37 citations

Effects of CCK-8 in the nucleus accumbens

1984 • 33 citations

Studies on Cholecystokinin‐containing Neuronal Pathways in Rat Cerebral Cortex and Striatuma

1985 • 30 citations

Effects of phencyclidine on extracellular levels of dopamine, dihydroxyphenylacetic acid and homovanillic acid in conscious and anesthetized rats

1990 • 30 citations

Immunohistochemical evidence for a crossed cholecystokinin corticostriatal pathway in the rat

1992 • 27 citations

Cholecystokinin is released from a crossed corticostriatal pathway

1992 • 25 citations

Cholecystokinin Potentiation of Dopamine‐mediated Behaviors in the Nucleus Accumbens

1985 • 18 citations

The effects of intraperitoneally administered phencyclidine on the central nervous system: Behavioral and neurochemical studies

1991 • 11 citations

A novel series of non-peptide CCK and gastrin antagonists: medicinal chemistry and electrophysiological demonstration of antagonism

1992 • 10 citations

Bilateral ablation of frontal cortex reduces concentration of cholecystokinin-like immunoreactivity in rat dorsolateral striatum

1988 • 10 citations

Antagonism of ceruletide, a cholecystokinin analog, to the neurochemical effects of the non-competitive N-methyl-D-aspartate (NMDA) receptor antagonists, phencyclidine and MK-801, on regional dopaminergic neurons in the rat brain

1992 • 6 citations

Detection of CCK receptor subtypes in mammalian brain using highly selective non-peptide antagonists

1992 • 5 citations

Preface

1985 • 4 citations

Synthesis of non-peptide CCK antagonists

1992 • 1 citations