Phencyclidine- and Dizocilpine-Induced Hyperlocomotion Are Differentially Mediated

Recent advances in the phencyclidine model of schizophrenia

1991 • 2,886 citations

The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.

1986 • 1,814 citations

Study of a New Schizophrenomimetic Drug—Sernyl

1959 • 922 citations

Nonparametric Statistical Methods

1974 • 861 citations

Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia

1980 • 703 citations

Identification, characterization, and localization of the dopamine D3 receptor in rat brain using 7-[3H]hydroxy-N,N-di-n-propyl-2-aminotetralin.

1992 • 672 citations

Amphetamine, cocaine, phencyclidine and nomifensine increase extracellular dopamine concentrations preferentially in the nucleus accumbens of freely moving rats

1989 • 562 citations

The NMDA antagonist MK-801 causes marked locomotor stimulation in monoamine-depleted mice

1989 • 426 citations

Pharmacology of human dopamine D3 receptor expressed in a mammalian cell line: comparison with D2 receptor

1992 • 402 citations

Evidence that LY-141865 specifically stimulates the D-2 dopamine receptor

1981 • 344 citations

The behavioral pharmacology of NMDA receptor antagonists

1990 • 331 citations

A “Glutamatergic Hypothesis” of Schizophrenia

1989 • 270 citations

Effects of neuroleptics on 3H-haloperidol and 3H-CIS (Z)-flupenthixol binding and on adenylate cyclase activity in vitro

1978 • 261 citations

NMDA receptors and in vivo dopamine release in the nucleus accumbens and caudatus

1990 • 221 citations

The selective dopamine D2 receptor antagonist raclopride discriminates between dopamine-mediated motor functions

1986 • 215 citations

Remoxipride, a new potential antipsychotic compound with selective anti-dopaminergic actions in the rat brain

1984 • 213 citations

Comparison of the behavioral and biochemical effects of the NMDA receptor antagonists, MK-801 and phencyclidine

1989 • 205 citations

Stimulation of both D1 and D2 dopamine receptors appears necessary for full expression of postsynaptic effects of dopamine agonists: a neurophysiological study

1987 • 193 citations

Behavioural effects of the putative D-3 dopamine receptor agonist 7-OH-DPAT in relation to other “D-2-like” agonists

1993 • 183 citations

The effects of phencyclidine and N-allylnormetazocine on midbrain dopamine neuronal activity

1984 • 181 citations

Effect of the NMDA receptor antagonist, MK-801, on locomotor activity and on the metabolism of dopamine in various brain areas of mice

1991 • 141 citations

MK-801-induced stereotypy and its antagonism by neuroleptic drugs

1990 • 138 citations

Typical and atypical neuroleptics antagonize MK-801-induced locomotion and stereotypy in rats

1992 • 122 citations

Effects of dizocilpine (MK-801) on rat midbrain dopamine cell activity: differential actions on firing pattern related to anatomical localization

1993 • 111 citations

Effects of Remoxipride and some Related New Substituted Salicylamides on Rat Brain Receptors

1986 • 101 citations

Do autoreceptors mediate dopamine agonist — induced yawning and suppression of exploration? A critical review

1992 • 86 citations

Effect of MK-801 on endogenous dopamine release in vivo

1990 • 77 citations

Neuropharmacological and behavioural properties of remoxipride in the rat

1990 • 71 citations

Selective activation of dopaminergic pathways in the mesocortex by compounds that act at the phencyclidine (pcp) binding site: tentative evidence for pcp recognition sites not coupled to n-methyl-d-aspartate (nmda) receptors

1990 • 71 citations

Phencyclidine-induced locomotor activity in the rat is blocked by 6-hydroxydopamine lesion of the nucleus accumbens: Comparisons to other psychomotor stimulants

1983 • 68 citations

Phencyclidine binding sites in the nucleus accumbens and phencyclidine-induced hyperactivity are decreased following lesions of the mesolimbic dopamine system

1985 • 65 citations

In vivo assessment of release and metabolism of dopamine in the ventrolateral striatum of awake rats following administration of dopamine D1 and D2 receptor agonists and antagonists

1991 • 64 citations

Motor responses to dopamine D1 and D2 agonists in the reserpine-treated mouse are affected differentially by the NMDA receptor antagonist MK 801

1992 • 60 citations

The topography of MK-801-induced locomotor patterns in rats

1989 • 53 citations

A comparison between classes of drugs having phencyclidine-like behavioral properties on dopamine efflux in vitro and dopamine metabolism in vivo.

1984 • 50 citations

Binding characteristics of remoxipride and its metabolites to dopamine D2 and D3 receptors

1993 • 48 citations

BEHAVIOURAL EFFECTS OF ERGOT DRUGS

1979 • 40 citations

Regulation of [3H]dopamine release from guinea pig striatum by NMDA receptor/channel activators and inhibitors.

1990 • 35 citations

Effects of phencyclidine on extracellular levels of dopamine, dihydroxyphenylacetic acid and homovanillic acid in conscious and anesthetized rats

1990 • 30 citations

The dopamine D2 antagonist remoxipride acts in vivo on a subpopulation of dopamine D2 receptors

1994 • 21 citations

Regional distribution and in vivo binding of the atypical antipsychotic drug remoxipride. A biochemical and autoradiographic analysis in the rat brain

1992 • 20 citations

Molecular Neurobiology Of Glutamate Receptors

1992 • 16 citations

Catecholamine Release within the Striatum of the Freely Moving Rat

1986 • 11 citations

Sites For Antagonism On The N-Methyl-D-Aspartate Receptor Channel Complex

1991 • 6 citations

Neuropharmacology Of Phencyclidine: Basic Mechanisms And Therapeutic Potential

1990 • 3 citations