Tryptophan hydroxylase gene associated with paroxetine antidepressant activity

Statistical power analysis for the behavioral sciences

1990 • 65,781 citations

Statistical Power Analysis for the Behavioral Sciences

1989 • 11,738 citations

Development of a Rating Scale for Primary Depressive Illness

1967 • 8,216 citations

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1991 • 2,314 citations

Linkage strategies for genetically complex traits. I. Multilocus models.

1990 • 1,335 citations

Some Conceptual and Statistical Issues in Analysis of Longitudinal Psychiatric Data

1993 • 728 citations

Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine

1998 • 605 citations

Relapse of depression after rapid depletion of tryptophan

1997 • 421 citations

Allelic Variation in the Serotonin Transporter Promoter Affects Onset of Paroxetine Treatment Response in Late-Life Depression

2000 • 410 citations

Serotonin transporter gene polymorphism and antidepressant response

2000 • 392 citations

Suicidality and 5-Hydroxyindoleacetic Acid Concentration Associated With a Tryptophan Hydroxylase Polymorphism

1994 • 378 citations

A Tryptophan Hydroxylase Gene Marker for Suicidality and Alcoholism

1998 • 305 citations

Pharmacogenetics and the serotonin system: initial studies and future directions

2000 • 282 citations

Association Between the Tryptophan Hydroxylase Gene and Manic-depressive Illness

1998 • 206 citations

Association of unipolar major depressive disorder with genes of the serotonergic and dopaminergic pathways

1999 • 181 citations

Possible association of a polymorphism of the tryptophan hydroxylase gene with suicidal behavior in depressed patients

1997 • 179 citations

Influence of a Functional Polymorphism Within the Promoter of the Serotonin Transporter Gene on the Effects of Total Sleep Deprivation in Bipolar Depression

1999 • 167 citations

Sequence, splice site and population frequency distribution analyses of the polymorphic human tryptophan hydroxylase intron 7

1997 • 166 citations

DIFFERENTIATION OF TWO GENETICALLY SPECIFIC TYPES OF DEPRESSION BY THE RESPONSE TO ANTI-DEPRESSANTS

1962 • 165 citations

How Long Should Pindolol Be Associated With Paroxetine to Improve the Antidepressant Response?

1997 • 157 citations

Familial concordance of fluvoxamine response as a tool for differentiating mood disorder pedigrees

1998 • 155 citations

Preface

1993 • 152 citations

Tryptophan hydroxylase and catechol-O-methyltransferase gene polymorphisms: relationships to monoamine metabolite concentrations in CSF of healthy volunteers

1997 • 126 citations

Double-blind controlled trial of sertraline versus paroxetine in the treatment of delusional depression

1996 • 120 citations

L-Tryptophan in Neuropsychiatry Disorders: A Review

1992 • 118 citations

Association between obsessive-compulsive disorder and polymorphisms of genes encoding components of the serotonergic and dopaminergic pathways

2000 • 118 citations

Pharmacogenetic response to antidepressants in a multicase family with affective disorder

1994 • 116 citations

Linkage of DFNB1 to Non-Syndromic Neurosensory Autosomal-Recessive Deafness in Mediterranean Families

1997 • 104 citations

Localization of human tryptophan hydroxylase (TPH) to chromosome 11p15.3→p14 by in situ hybridization

1991 • 103 citations

Linkage of DFNB1 to non-syndromic neurosensory autosomal-recessive deafness in Mediterranean families.

1997 • 102 citations

Advances in the molecular characterization of tryptophan hydroxylase

1998 • 96 citations

Identification of four variants in the tryptophan hydroxylase promoter and association to behavior

1999 • 93 citations

No coding variant of the tryptophan hydroxylase gene detected in seasonal affective disorder, obsessive–compulsive disorder, anorexia nervosa, and alcoholism

1999 • 89 citations

No association of the tryptophan hydroxylase gene with bipolar affective disorder, unipolar affective disorder, or suicidal behaviour in major affective disorder.

1998 • 85 citations

Genetic Association Analysis of Serotonin System Genes in Bipolar Affective Disorder

1999 • 83 citations

Suicidal Behaviors and the Tryptophan Hydroxylase Gene

1995 • 83 citations

Population Studies of Polymorphisms at Loci of Neuropsychiatric Interest (Tryptophan Hydroxylase (TPH), Dopamine Transporter Protein (SLC6A3), D3 Dopamine Receptor (DRD3), Apolipoprotein E (APOE), μ Opioid Receptor (OPRM1), and Ciliary Neurotrophic Factor (CNTF))

1998 • 78 citations

Complete coding sequence of human tryptophan hydroxylase

1990 • 78 citations

Impulsiveness, serotonin genes and repetition of deliberate self-harm (DSH)

2000 • 76 citations

Pharmacogenomics of psychiatric disorders

2001 • 76 citations

Outcomes on lithium treatment as a tool for genetic studies in affective disorders

1984 • 72 citations

Tryptophan hydroxylase polymorphisms in suicide victims

2000 • 72 citations

No association of the tryptophan hydroxylase gene with bipolar affective disorder, unipolar affective disorder, or suicidal behaviour in major affective disorder

1998 • 69 citations

Assessing psychopathology in Chinese psychiatric patients in Hong Kong using the Brief Psychiatric Rating Scale

1993 • 58 citations

TPH Gene May Be Associated with Suicidal Behavior, but Not with Schizophrenia in the Korean Population

2000 • 55 citations

Lithium-responsive affective disorders: no association with the tyrosine hydroxylase gene

1996 • 53 citations

Mode of inheritance in mood disorder families according to fluvoxamine response

1998 • 52 citations

No association between chromosome-18 markers and lithiumresponsive affective disorders

1996 • 51 citations

Progress and pitfalls: bipolar molecular linkage studies

1998 • 50 citations

Plasma Tryptophan to Large Neutral Amino Acids Ratio and Therapeutic Response to a Selective Serotonin Uptake Inhibitor

1994 • 48 citations

Tryptophan hydroxylase gene polymorphisms are not associated with suicide

2000 • 38 citations

ANXIOUS DEPRESSION-ASSESSMENT AND TREATMENT

1988 • 38 citations

Use of tryptophan in combination with other antidepressant treatments: a review.

1991 • 35 citations

Anxious depression : assessment and treatment

1987 • 33 citations

The search for genetic homogeneity in affective disorders

1984 • 32 citations

Genetic association study in psychiatry: Analytical evaluation and a recommendation

1994 • 30 citations

The 5′ region of the tryptophan hydroxylase gene: mutation search and association study with alcoholism

1999 • 26 citations

Patterns of symptom improvement during antidepressant treatment of delusional depression

2000 • 24 citations

Association study of the tryptophan hydroxylase gene and bipolar affective disorder using family-based internal controls

2000 • 17 citations