Tryptophan hydroxylase and catechol-O-methyltransferase gene polymorphisms: relationships to monoamine metabolite concentrations in CSF of healthy volunteers

Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders

1996 • 1,780 citations

Diagnostic and Statistical Manual of Mental Disorders (DSM-III-R)

1987 • 1,599 citations

Enzymatic O-Methylation of Epinephrine and Other Catechols

1958 • 1,291 citations

Neurosteroids: Endogenous bimodal modulators of the GABAA receptor mechanism of action and physiological significance

1992 • 1,098 citations

Catechol-O-methyl transferase: pharmacological aspects and physiological role.

1975 • 547 citations

Fluoxetine in the Treatment of Premenstrual Dysphoria

1995 • 445 citations

Suicidality and 5-Hydroxyindoleacetic Acid Concentration Associated With a Tryptophan Hydroxylase Polymorphism

1994 • 378 citations

Chromosomal mapping of the human catechol-O-methyltransferase gene to 22q11.1→q11.2

1992 • 295 citations

Paternal and Maternal Genetic and Environmental Contributions to Cerebrospinal Fluid MonoamineMetabolites in Rhesus Monkeys (Macaca mulatta)

1993 • 254 citations

Human liver catechol-O-methyltransferase pharmacogenetics

1990 • 243 citations

Simultaneous determination of the three major monoamine metabolites in brain tissue and body fluids by a mass fragmentographic method

1976 • 229 citations

Interacting neurotransmitter systems. A non-experimental approach to the 5hiaa-hva correlation in human CSF

1986 • 202 citations

Ovarian Steroid Regulation of Tryptophan Hydroxylase mRNA Expression in Rhesus Macaques

1996 • 193 citations

Relationships in Healthy Volunteers Between Concentrations of Monoamine Metabolites in Cerebrospinal Fluid and Family History of Psychiatric Morbidity

1980 • 176 citations

Concentrations of monoamine metabolites in the cerebrospinal fluid of twins and unrelated individuals—A genetic study

1986 • 174 citations

Sequence, splice site and population frequency distribution analyses of the polymorphic human tryptophan hydroxylase intron 7

1997 • 166 citations

Binding of Progesterone to Nerve Cell Membranes of Rat Brain Using Progesterone Conjugated to ¹²⁵I‐Bovine Serum Albumin as a Ligand

1990 • 153 citations

No evidence for allelic association between schizophrenia and a polymorphism determining high or low catechol O-methyltransferase activity

1996 • 149 citations

Localization of human tryptophan hydroxylase (TPH) to chromosome 11p15.3→p14 by in situ hybridization

1991 • 103 citations

Dopamine D2-receptor gene polymorphisms in scandinavian chronic alcoholics

1994 • 100 citations

The enzymic oxidation of tryptophan to 5-hydroxytryptophan in the biosynthesis of serotonin.

1961 • 98 citations

Dopamine-related genes and their relationships to monoamine metabolites in CSF

1996 • 93 citations

Suicidal Behaviors and the Tryptophan Hydroxylase Gene

1995 • 83 citations

The human catechol-O-methyltransferase (COMT) gene maps to band q11.2 of chromosome 22 and shows a frequent RFLP with <i>Bgl</i>I

1992 • 81 citations

Genetic mapping of the human tryptophan hydroxylase gene on chromosome 11, using an intronic conformational polymorphism.

1992 • 78 citations

Differential control of tryptophan hydroxylase expression in raphe and in pineal gland: Evidence for a role of translation efficiency

1989 • 68 citations

Effect of clomipramine on premenstrual syndrome

1990 • 54 citations

Cerebrospinal Fluid Levels of Monoamine Metabolites

1994 • 52 citations

SSCP primer design based on single-strand DNA structure predicted by a DNA folding program

1995 • 35 citations

Clinical investigation of monoamine neurotransmitter interactions

1993 • 31 citations

Assignment of the catechol-O-methyltransferase gene to human chromosome 22 in somatic cell hybrids

1986 • 28 citations

Low catechol-O-methyltransferase activity in a Saami population

1994 • 18 citations

Determination of Serotonin in Small Brain Structures by Means of HPLC Combined with Electrochemical Detection: The Effect of Ovarian Steroids on Serotonin Turnover Rate within Several Brain Regions of the Ovariectomized Rat

1983 • 3 citations

Deleted Work

1955 • 0 citations