The Role of Estrogen in the Control of Rat Osteocyte Apoptosis

Cell Death: The Significance of Apoptosis

1980 • 7,281 citations

Programmed cell death involved in the schizolysigenous formation of the secretory cavity in Citrus sinensis L. (Osbeck)

2010 • 1,629 citations

Estrogen promotes apoptosis of murine osteoclasts mediated by TGF–β

1996 • 799 citations

Neuroprotection against Oxidative Stress by Estrogens: Structure-Activity Relationship

1997 • 769 citations

Sensitivity of osteocytes to biomechanical stress in vitro

1995 • 768 citations

Long-term effects of ovariectomy and aging on the rat skeleton

1989 • 457 citations

Using functional loading to influence bone mass and architecture: objectives, mechanisms, and relationship with estrogen of the mechanically adaptive process in bone

1996 • 427 citations

Osteocytes, strain detection, bone modeling and remodeling

1993 • 425 citations

Apoptosis is abundant in human atherosclerotic lesions, especially in inflammatory cells (macrophages and T cells), and may contribute to the accumulation of gruel and plaque instability.

1996 • 420 citations

Function of osteocytes in bone

1994 • 402 citations

The Death of Osteocytes via Apoptosis Accompanies Estrogen Withdrawal in Human Bone*

1997 • 386 citations

Early strain-related changes in enzyme activity in osteocytes following bone loading in vivo

1989 • 357 citations

Mechanical strain-induced NO production by bone cells: a possible role in adaptive bone (re)modeling?

1995 • 332 citations

Estrogen-Receptor–Mediated Inhibition of Human Endothelial Cell Apoptosis

1997 • 284 citations

Simultaneous block of interleukin-1 and tumor necrosis factor is required to completely prevent bone loss in the early postovariectomy period.

1995 • 257 citations

Identification of apoptotic changes in osteocytes in normal and pathological human bone

1997 • 231 citations

Mechanically regulated expression of a neural glutamate transporter in bone: A role for excitatory amino acids as osteotropic agents?

1997 • 214 citations

Apoptotic neutrophils are phagocytosed by fibroblasts with participation of the fibroblast vitronectin receptor and involvement of a mannose/fucose-specific lectin.

1994 • 213 citations

Cellular responses to mechanical loading in vitro

1990 • 202 citations

In Vivo Osteocyte Death

1960 • 190 citations

The Death of Osteocytes via Apoptosis Accompanies Estrogen Withdrawal in Human Bone

1997 • 174 citations

Estrogen and apoptosis in the developing sexually dimorphic preoptic area in female rats

1996 • 164 citations

Multiple Pathways for Apoptotic Nuclear Fragmentation

1996 • 157 citations

A quantitative histologic analysis of the growing long bone metaphysis

1980 • 143 citations

Function of Osteocytes in Bone—Their Role in Mechanotransduction

1995 • 137 citations

Techniques in apoptosis: A user's guide

1997 • 134 citations

Multiple systems for recognition of apoptotic lymphocytes by macrophages.

1997 • 133 citations

Perspectives: Mechanical loading, estrogen deficiency, and the coupling of bone formation to bone resorption

1991 • 133 citations

Experimental Osteonecrosis of the Femoral Head in Adult Rabbits

1978 • 120 citations

Preliminary in situ identification of estrogen target cells in bone

1995 • 110 citations

Bone age, mineral density, and fatigue damage

1993 • 107 citations

Osteocyte death and hip fracture

1993 • 96 citations

Morphological Evidence of Apoptosis and the Prevalence of Apoptotic versus Mitotic Cells in the Membrana Granulosa of Ovarian Follicles during Spontaneous and Induced Atresia in Ewes

1997 • 94 citations

Nondestructive measurement of bone mineral in femurs from ovariectomized rats

1990 • 92 citations

Size and density of osteocyte lacunae in different regions of long bones

1982 • 76 citations

Long-term effects of ovariectomy on the mechanical properties and chemical composition of rat bone

1997 • 68 citations

Bone death in hip fracture in the elderly

1990 • 61 citations

The Pathogenesis of Osteoarthritis of the Hip

1987 • 53 citations

Clinical significance of bcl-2 gene expression in human breast cancer tissues

1997 • 53 citations

bcl-2 is down-regulated in atypical endometrial hyperplasia and adenocarcinoma.

1996 • 51 citations

Inhibitory effects of estrogen, progesterone, androgen and glucocorticoid on death of neonatal mouse uterine epithelial cells induced to proliferate by estrogen

1993 • 47 citations

Isolated chick osteocytes stimulate formation and bone-resorbing activity of osteoclast-like cells

1995 • 43 citations

Variability of Glutathione Levels in Normal Breast Tissue and Subcutaneous Fat during the Menstrual Cycle: An in Vivo Study with Microdialysis Technique*

1997 • 41 citations

Persistent bone-sparing effect of interleukin-1 receptor antagonist: A hypothesis on the role of IL-1 in ovariectomy-induced bone loss

1994 • 38 citations

Inhibition of Osteopenia by Biophysical Intervention

2001 • 22 citations