Serotoninergic regulation of emotional and behavioural control processes

A Neural Substrate of Prediction and Reward

1997 • 8,991 citations

Influence of Life Stress on Depression: Moderation by a Polymorphism in the 5-HTT Gene

2003 • 8,039 citations

Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region

1996 • 5,154 citations

Anterior Cingulate Cortex, Error Detection, and the Online Monitoring of Performance

1998 • 3,235 citations

Serotonin Transporter Genetic Variation and the Response of the Human Amygdala

2002 • 2,332 citations

A framework for mesencephalic dopamine systems based on predictive Hebbian learning

1996 • 2,003 citations

5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depression

2005 • 1,973 citations

Varieties of impulsivity

1999 • 1,967 citations

By Carrot or by Stick: Cognitive Reinforcement Learning in Parkinsonism

2004 • 1,951 citations

The Biochemical Basis of Neuropharmacology.

1974 • 1,911 citations

Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: A hypothesis for the etiology of schizophrenia

1991 • 1,819 citations

5-HT and mechanisms of defence

1991 • 1,017 citations

Reconciling the role of central serotonin neurons in human and animal behavior

1986 • 989 citations

Role of 5-HT in stress, anxiety, and depression

1996 • 972 citations

Medial prefrontal cortex determines how stressor controllability affects behavior and dorsal raphe nucleus

2005 • 919 citations

Role of locus coeruleus in attention and behavioral flexibility

1999 • 867 citations

Opponent interactions between serotonin and dopamine

2002 • 821 citations

Fear, Vigilance, and Ambiguity

1998 • 792 citations

Defining the Neural Mechanisms of Probabilistic Reversal Learning Using Event-Related Functional Magnetic Resonance Imaging

2002 • 760 citations

Tryptophan depletion causes a rapid lowering of mood in normal males

1985 • 726 citations

Amygdala-prefrontal coupling depends on a genetic variation of the serotonin transporter

2004 • 700 citations

Genetics of emotional regulation: the role of the serotonin transporter in neural function

2006 • 661 citations

Induced emotional interpretation bias and anxiety.

2000 • 657 citations

Cognitive Inflexibility After Prefrontal Serotonin Depletion

2004 • 629 citations

Neurochemical Modulation of Response Inhibition and Probabilistic Learning in Humans

2006 • 560 citations

Increased Positive Versus Negative Affective Perception and Memory in Healthy Volunteers Following Selective Serotonin and Norepinephrine Reuptake Inhibition

2004 • 527 citations

5-Hydroxytryptamine-interacting drugs in animal models of anxiety disorders: More than 30 years of research

1995 • 497 citations

Cognitive performance in tests sensitive to frontal lobe dysfunction in the elderly depressed

1996 • 457 citations

Central Serotonin and Impulsive Aggression

1989 • 456 citations

Central 5-HT depletion enhances impulsive responding without affecting the accuracy of attentional performance: interactions with dopaminergic mechanisms

1997 • 455 citations

Antidepressant Drug Treatment Modifies the Neural Processing of Nonconscious Threat Cues

2006 • 448 citations

Acute SSRI Administration Affects the Processing of Social Cues in Healthy Volunteers

2003 • 414 citations

The Biochemical Basis of Neuropharmacology

2003 • 376 citations

Aggression, suicidality, and serotonin.

1992 • 348 citations

Cognitive Inflexibility after Prefrontal Serotonin Depletion Is Behaviorally and Neurochemically Specific

2006 • 344 citations

5-HT2A and 5-HT2C receptor antagonists have opposing effects on a measure of impulsivity: interactions with global 5-HT depletion

2004 • 322 citations

Tryptophan Depletion During Continuous CSF Sampling in Healthy Human Subjects

1998 • 298 citations

Neuropsychological impairment in patients with major depressive disorder: the effects of feedback on task performance

2003 • 289 citations

Differential Effects of 6-OHDA Lesions of the Frontal Cortex and Caudate Nucleus on the Ability to Acquire an Attentional Set

2001 • 284 citations

Abnormal response to negative feedback in unipolar depression: evidence for a diagnosis specific impairment

1997 • 279 citations

Serotonin and Drug-Induced Therapeutic Responses in Major Depression, Obsessive–Compulsive and Panic Disorders

1999 • 279 citations

Tryptophan Depletion Alters the Decision-Making of Healthy Volunteers through Altered Processing of Reward Cues

2002 • 273 citations

Effect of a Triallelic Functional Polymorphism of the Serotonin-Transporter-Linked Promoter Region on Expression of Serotonin Transporter in the Human Brain

2006 • 262 citations

Global 5-HT depletion attenuates the ability of amphetamine to decrease impulsive choice on a delay-discounting task in rats

2003 • 258 citations

The effects of tryptophan depletion on cognitive and affective processing in healthy volunteers

2002 • 252 citations

The selective serotonin reuptake inhibitor citalopram increases fear after acute treatment but reduces fear with chronic treatment: a comparison with tianeptine

2004 • 244 citations

Chemistry of the adaptive mind

2004 • 242 citations

A single dose of citalopram increases fear recognition in healthy subjects

2007 • 240 citations

Serotonergic Modulation of Prefrontal Cortex during Negative Feedback in Probabilistic Reversal Learning

2005 • 206 citations

Dissociable roles of the ventral, medial and lateral striatum on the acquisition and performance of a complex visual stimulus-response habit

1991 • 204 citations

Opposing effects of 5-HT2A and 5-HT2C receptor antagonists in the rat and mouse on premature responding in the five-choice serial reaction time test

2007 • 200 citations

GABAergic Antagonists Block the Inhibitory Effects of Serotonin in the Lateral Amygdala: A Mechanism for Modulation of Sensory Inputs Related to Fear Conditioning

1999 • 194 citations

Stop signal response inhibition is not modulated by tryptophan depletion or the serotonin transporter polymorphism in healthy volunteers: implications for the 5-HT theory of impulsivity

2005 • 175 citations

Acute Tryptophan Depletion in Healthy Volunteers Enhances Punishment Prediction but Does not Affect Reward Prediction

2007 • 167 citations

Tryptophan depletion decreases the recognition of fear in female volunteers

2003 • 163 citations

Individual differences in threat sensitivity predict serotonergic modulation of amygdala response to fearful faces

2005 • 157 citations

Effect of tryptophan depletion on impulsive behavior in men with or without a family history of alcoholism

2002 • 156 citations

Central serotonin depletion impairs both the acquisition and performance of a symmetrically reinforced go/no-go conditional visual discrimination

1999 • 152 citations

Inhibition: History and Meaning in the Sciences of Mind and Brain

1995 • 149 citations

Behavioral Disinhibition Induced by Tryptophan Depletion in Nonalcoholic Young Men With Multigenerational Family Histories of Paternal Alcoholism

1999 • 149 citations

Serotonin Modulation of Sensory Inputs to the Lateral Amygdala: Dependency on Corticosterone

1998 • 147 citations

Lowering of serotonin by rapid tryptophan depletion increases impulsiveness in normal individuals

2002 • 146 citations

Tryptophan Depletion Disrupts the Motivational Guidance of Goal-Directed Behavior as a Function of Trait Impulsivity

2005 • 145 citations

Treatment of obsessive-compulsive spectrum disorders with SSRIs

1998 • 136 citations

Dissociable effects of anterior and posterior cingulate cortex lesions on the acquisition of a conditional visual discrimination: Facilitation of early learning vs. impairment of late learning

1996 • 125 citations

Effects of Acute Tryptophan Depletion on Mood and Facial Emotion Perception Related Brain Activation and Performance in Healthy Women with and without a Family History of Depression

2006 • 112 citations

Selective serotonin reuptake inhibitor reduces conditioned fear through its effect in the amygdala

2004 • 105 citations

Effect of conditioned fear stress on serotonin metabolism in the rat brain

1993 • 105 citations

Serotonergic activation reduces defensive freezing in the conditioned fear paradigm

1996 • 104 citations

Amygdala Response to Facial Expressions Reflects Emotional Learning

2006 • 100 citations

Serotonin Transporter Polymorphism Mediates Vulnerability to Loss of Incentive Motivation Following Acute Tryptophan Depletion

2006 • 94 citations

Anxious Behavior and Fenfluramine-Induced Prolactin Secretion in Young Rhesus Macaques with Different Alleles of the Serotonin Reuptake Transporter Polymorphism (5HTTLPR)

2004 • 94 citations

The Impact of Tryptophan Depletion and 5-HTTLPR Genotype on Passive Avoidance and Response Reversal Instrumental Learning Tasks

2006 • 85 citations

The Effect of Acute Tryptophan Depletion on the Neural Correlates of Emotional Processing in Healthy Volunteers

2007 • 80 citations

Involvement of a polymorphism in the 5-HT2A receptor gene in impulsive behavior

2006 • 79 citations

Effect of chronic administration of flesinoxan and fluvoxamine on freezing behavior induced by conditioned fear

2001 • 76 citations

Performance feedback deficit in geriatric depression

2001 • 70 citations

Effects of a novel method of acute tryptophan depletion on plasma tryptophan and cognitive performance in healthy volunteers

2004 • 65 citations

Local 5,7-Dihydroxytryptamine Lesions of Rat Amygdala Release of Punished Drinking, Unaffected Plus-Maze Behavior and Ethanol Consumption

2001 • 51 citations

d-fenfluramine-induced prolactin responses in mania: evidence for serotonergic subsensitivity

1996 • 43 citations

Forebrain serotonin depletion facilitates the acquisition and performance of a conditional visual discrimination task in rats

1999 • 40 citations

Differential Effects of Forebrain 5‐Hydroxytryptamine Depletions on Pavlovian Aversive Conditioning to Discrete and Contextual Stimuli in the Rat

1995 • 34 citations

Inhibition: history and meaning in the sciences of mind and brain

1993 • 24 citations

Acquisition of Conditioned Inhibition in Rats is Impaired by Ablation of Serotoninergic Pathways

1996 • 17 citations