[29] Production and assay of antibodies to acetylcholine receptors

Continuous cultures of fused cells secreting antibody of predefined specificity

1975 • 17,037 citations

Production of monoclonal antibodies: Strategy and tactics

1980 • 1,594 citations

Antibody to acetylcholine receptor in myasthenia gravis

1998 • 1,149 citations

Antibody to acetylcholine receptor in myasthenia gravis: Prevalence, clinical correlates, and diagnostic value

1976 • 1,123 citations

Autoimmune Response to Acetylcholine Receptor

1973 • 1,019 citations

Acetylcholine Receptor: Complex of Homologous Subunits

1980 • 594 citations

Affinity Chromatography

1971 • 504 citations

A simple assay for the study of solubilized acetylcholine receptors

1973 • 416 citations

Rat × rat hybrid myelomas and a monoclonal anti-Fd portion of mouse IgG

1979 • 411 citations

The Cell surface and neuronal function

1980 • 379 citations

Acetylcholine receptor turnover in membranes of developing muscle fibers.

1975 • 364 citations

Experimental autoimmune myasthenia: A model of myasthenia gravis in rats and guinea pigs.

1975 • 325 citations

ANTIGENS OF LEUKEMIAS INDUCED BY NATURALLY OCCURRING MURINE LEUKEMIA VIRUS: THEIR RELATION TO THE ANTIGENS OF GROSS VIRUS AND OTHER MURINE LEUKEMIA VIRUSES

1966 • 287 citations

An assay for antibodies to human acetylcholine receptor in serum from patients with myasthenia gravis

1977 • 283 citations

EXPERIMENTAL AUTOIMMUNE MYASTHENIA GRAVIS AND MYASTHENIA GRAVIS: BIOCHEMICAL AND IMMUNOCHEMICAL ASPECTS*

1976 • 275 citations

Myasthenic Immunoglobulin Accelerates Acetylcholine Receptor Degradation

1977 • 260 citations

Solid state lactoperoxidase: A highly stable enzyme for simple, gentle iodination of proteins

1972 • 257 citations

Synaptic transmission and neuronal interaction

1975 • 256 citations

Immunology of acetylcholine receptors in relation to myasthenia gravis.

1980 • 255 citations

Isolation of the Principal Neurotoxins of Two Naja naja Subspecies

1971 • 248 citations

The Acetylcholine Receptor

1973 • 245 citations

Biochemical properties of acetylcholine receptor subunits from Torpedo californica

1979 • 239 citations

Role of complement in the pathogenesis of experimental autoimmune myasthenia gravis.

1978 • 239 citations

Ultrastructural Localization of the Terminal and Lytic Ninth Complement Component (C9) at the Motor End-plate in Myasthenia Gravis

1980 • 210 citations

Myasthenia gravis induced by monoclonal antibodies to acetylcholine receptors

1980 • 201 citations

Purification and molecular properties of the acetylcholine receptor from Torpedo electroplax

1973 • 201 citations

Studies of the composition of purified Torpedo californica acetylcholine receptor and of its subunits

1979 • 193 citations

Molecular forms of acetylcholine receptor. Effects of calcium ions and a sulfhydryl reagent on the occurrence of oligomers

1977 • 185 citations

EXPERIMENTAL AUTOIMMUNE MYASTHENIA GRAVIS: CELLULAR AND HUMORAL IMMUNE RESPONSES*

1976 • 185 citations

Purification of acetylcholine receptors, reconstitution into lipid vesicles, and study of agonist-induced cation channel regulation.

1980 • 182 citations

Purification of acetylcholine receptors from Torpedo claifornica electroplax by affinity chromatography

1973 • 176 citations

Reconstitution of carbamylcholine-dependent sodium ion flux and desensitization of the acetylcholine receptor from Torpedo californica.

1978 • 176 citations

Pathological mechanisms in experimental autoimmune myasthenia gravis. I. Immunogenicity of syngeneic muscle acetylcholine receptor and quantitative extraction of receptor and antibody-receptor complexes from muscles of rats with experimental automimmune myasthenia gravis.

1976 • 175 citations

Affinity labeling of one of two α-neurotoxin binding sites in acetylcholine receptor from Torpedo californica

1978 • 163 citations

Monoclonal antibodies as probes of acetylcholine receptor structure. 2. Binding to native receptor

1981 • 157 citations

Experimental myasthenia gravis. A murine system.

1980 • 153 citations

Immunospecific identification and three-dimensional structure of a membrane-bound acetylcholine receptor from Torpedo californica

1979 • 153 citations

The subunit structure of rat liver insulin receptor. Antibodies directed against the insulin-binding subunit.

1980 • 144 citations

Autoimmune Response to Acetylcholine Receptors in Myasthenia Gravis and Its Animal Model

1979 • 143 citations

Strain differences in the autoimmune response of mice to acetylcholine receptors

1976 • 130 citations

Monoclonal anti-acetylcholine receptor antibodies can cause experimental myasthenia

1980 • 116 citations

Monoclonal antibodies as probes of acetylcholine receptor structure. 1. Peptide mapping

1981 • 115 citations

Ultrastructural Localization of Immune Complexes (IGG and C3) at the End-Plate in Experimental Autoimmune Myasthenia Gravis

1978 • 115 citations

Immunological characterisation of the cholinergic receptor protein from Electrophorus electricus

1973 • 113 citations

Immunochemical similarities between subunits of acetylcholine receptors from Torpedo, Electrophorus, and mammalian muscle

1979 • 110 citations

Experimental autoimmune myasthenia induced in monkeys by purified acetylcholine receptor

1975 • 106 citations

Monoclonal antibodies against purified nicotinic acetylcholine receptor

1979 • 97 citations

Specificities of antibodies to acetylcholine receptors

1978 • 95 citations

Passively transferred experimental autoimmune myasthenia gravis

1979 • 93 citations

Cell and Tissue Culture

2008 • 91 citations

Subunit structure and peptide mapping of junctional and extrajunctional acetylcholine receptors from rat muscle

1979 • 90 citations

Immunological comparison of acetylcholine receptors and their subunits from species of electric ray

1977 • 89 citations

Subunit structure of the acetylcholine receptor from denervated rat skeletal muscle

1977 • 86 citations

A radioimmunoassay for the quantitative evaluation of anti-human acetylcholine receptor antibodies in myasthenia gravis.

1977 • 82 citations

Genetic control of experimental autoimmune myasthenia gravis in mice. I. Lymphocyte proliferative response to acetylcholine receptors is under H-2-linked Ir gene control.

1979 • 79 citations

Acetylcholine receptors from Torpedo and Electrophorus have similar subunit structures

1980 • 73 citations

Cellular Neurobiology

1991 • 70 citations

Antigenic modulation and receptor loss in experimental autoimmune myasthenia gravis

1979 • 56 citations

Purification and characterization of an acetylcholine receptor from mammalian skeletal muscle

1977 • 54 citations

Genetic Control of Experimental Autoimmune Myasthenia Gravis in Mice

1979 • 52 citations

Passive transfer of experimental autoimmune myasthenia by lymph node cells in inbred guinea pigs.

1975 • 51 citations

Demonstration of the transmembrane nature of the acetylcholine receptor by labeling with anti-receptor antibodies.

1979 • 49 citations

Binding of antibodies to acetylcholine receptors in Electrophorus and Torpedo electroplax membranes.

1978 • 48 citations

Measurement of acetylcholine receptor and anti‐receptor antibodies by ELISA

1980 • 37 citations

Myasthenia in frogs immunized against cholinergic-receptor protein

1979 • 36 citations

Biochemistry of Myasthenia Gravis and Muscular Dystrophy

1979 • 35 citations

Properties of nicotinic acetylcholine receptors isolated by affinity chromatography on monoclonal antibodies.

1980 • 33 citations

EXPERIMENTAL MYASTHENIA IN RABBITS: BIOCHEMICAL, IMMUNOLOGICAL, ELECTROPHYSIOLOGICAL, AND MORPHOLOGICAL ASPECTS

1976 • 31 citations

Purification of high-affinity Fab fragments from experimental autoimmune Myasthenia gravis rabbits and their effect on isolated acetylcholine receptors

1979 • 17 citations