Disease Relevant HLA Class II Alleles Isolated by Genotypic, Haplotypic, and Sequence Analysis in North American Caucasians With Pemphigus Vulgaris

HLA‐DR typing by PCR amplification with sequence‐specific primers (PCR‐SSP) in 2 hours: An alternative to serological DR typing in clinical practice including donor‐recipient matching in cadaveric transplantation

1992 • 1,846 citations

The Autoimmune Diseases

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From Genotypes to Genes: Doubling the Sample Size

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A Molecular Basis for MHC Class II—Associated Autoimmunity

1988 • 707 citations

Autoimmune Diseases: The Failure of Self Tolerance

1990 • 495 citations

The genetics of complex autoimmune diseases: non-MHC susceptibility genes

2001 • 394 citations

Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: a family study.

1988 • 387 citations

Genetics of type 1 diabetes mellitus

2002 • 354 citations

Power and Sample Size Calculations for Case-Control Genetic Association Tests when Errors Are Present: Application to Single Nucleotide Polymorphisms

2002 • 289 citations

Structural basis for major histocompatibility complex (MHC)-linked susceptibility to autoimmunity: charged residues of a single MHC binding pocket confer selective presentation of self-peptides in pemphigus vulgaris.

1995 • 241 citations

A Newly Characterized HLA DQ _β Allele Associated with Pemphigus Vulgaris

1988 • 230 citations

Major histocompatibility complex haplotype studies in Ashkenazi Jewish patients with pemphigus vulgaris.

1990 • 226 citations

Independence tests for VNTR alleles defined as quantile bins.

1993 • 212 citations

HLA class II allelic variation and susceptibility to pemphigus vulgaris.

1988 • 211 citations

The HLA FactsBook

2000 • 179 citations

Could HLA-DRB1 be the protective locus in rheumatoid arthritis?

1995 • 178 citations

2LD, GENECOUNTING and HAP: computer programs for linkage disequilibrium analysis

2004 • 173 citations

New HLA haplotype frequency reference standards: High‐resolution and large sample typing of HLA DR‐DQ haplotypes in a sample of European Americans

2003 • 172 citations

Major histocompatibility complex haplotypes and class II genes in non-Jewish patients with pemphigus vulgaris.

1991 • 166 citations

Specific HLA-DQB and HLA-DRB1 alleles confer susceptibility to pemphigus vulgaris.

1989 • 118 citations

HLA Class II Polymorphism Contributes to Specify Desmoglein Derived Peptides in Pemphigus Vulgaris and Pemphigus Foliaceus

2000 • 118 citations

HLA-DQ-associated predisposition to and dominant HLA-DR-associated protection against rheumatoid arthritis

1999 • 114 citations

Detection of disease-specific restriction fragment length polymorphisms in pemphigus vulgaris linked to the DQw1 and DQw3 alleles of the HLA-D region.

1987 • 107 citations

Common Human Leukocyte Antigen Alleles in Pemphigus Vulgaris and Pemphigus Foliaceus Italian Patients

1999 • 106 citations

Comparative analysis of HLA polymorphism at the serologic and molecular level in Moroccan and Ashkenazi Jews

1995 • 103 citations

An investigation of the effect of misclassification on the properties of x,2-tests in the analysis of categorical data

1965 • 101 citations

Linkage of pemphigus vulgaris antibody to the major histocompatibility complex in healthy relatives of patients.

1993 • 94 citations

Evidence for negative association of the chemokine receptor CCR5 d32 polymorphism with rheumatoid arthritis

2004 • 83 citations

HLA class II associated risk and protection against multiple sclerosis—a Finnish family study

2002 • 77 citations

HLA-DRB1 alleles encoding an aspartic acid at position 70 protect against development of rheumatoid arthritis.

2001 • 77 citations

HLA-DRB1*04 and DRB1*14 Alleles Are Associated with Susceptibility to Pemphigus Among Japanese

1997 • 74 citations

Pemphigus Vulgaris Autoantibody Response is Linked to HLA-DQB10503 in Pakistani Patients

1997 • 70 citations

Distribution of HLA class II alleles among Spanish patients with pemphigus vulgaris

1998 • 68 citations

HLA haplotypes and class II molecular alleles in Sardinian and Italian patients with pemphigus vulgaris

1996 • 64 citations

Hla class II antigens assoiated with lupus nephritis in italian SLE patients

2003 • 61 citations

Heterogeneous MHC II Restriction Pattern of Autoreactive Desmoglein 3 Specific T Cell Responses in Pemphigus Vulgaris Patients and Normals

1998 • 60 citations

Significant Evidence for Linkage Disequilibrium over a 5-cM Region among Afrikaners

2000 • 59 citations

MHC class II alleles and haplotypes in patients with pemphigus vulgaris from India

1996 • 53 citations

Identical MHC Markers in Non-Jewish Iranian and Ashkenazi Jewish Patients with Pemphigus Vulgaris: Possible Common Central Asian Ancestral Origin

1997 • 53 citations

HLA Class II Restriction of Autoreactive T Cell Responses in Pemphigus Vulgaris: Review of the Literature and Potential Applications for the Development of a Specific Immunotherapy

1999 • 49 citations

HLA‐DQA1, ‐DQB1 and ‐DRB1 genotyping in Japanese pemphigus vulgaris patients by the PCR‐RFLP method

1994 • 49 citations

HLA-DRB1 polymorphisms and autoimmune responses to desmogleins in Japanese patients with pemphigus

1999 • 47 citations

Molecular analysis of HLA DRB1 and DQB1 in Italian patients with pemphigus vulgaris

1996 • 46 citations

The P9 pocket of HLA-DQ2 (non-Aspbeta57) has no particular preference for negatively charged anchor residues found in other type 1 diabetes- predisposing non-Aspbeta57 MHC class II molecules

1998 • 42 citations

HLA-DRB1 alleles encoding the “shared epitope” are associated with susceptibility to developing rheumatoid arthritis whereas HLA-DRB1 alleles encoding an aspartic acid at position 70 of the β-chain are protective in Mexican mestizos

2004 • 40 citations

HLA-DQ6-mediated protection in IDDM

2000 • 36 citations

Protection against severe disease is conferred by DERAA-bearing HLA-DRB1 alleles among HLA-DQ3 and HLA-DQ5 positive rheumatoid arthritis patients

2001 • 31 citations

Novel associations among HLA‐DQA1 and ‐DQB1 alleles, revealed by high‐resolution sequence‐based typing (SBT)

2000 • 29 citations

Polymorphisms of HLA class II genes in Japanese patients with pemphigus vulgaris

1998 • 23 citations

HLA‐DPB1*0401 is associated with dominant protection against type 1 diabetes in the general Saudi population and in subjects with a high‐risk DR/DQ haplotype

2003 • 19 citations

Haplotype associations of the MHC with psoriasis vulgaris in Chinese Hans

2004 • 17 citations

HLA Haplotypes and Class II Molecular Alleles in Argentinian Patients with Pemphigus Vulgaris

2002 • 16 citations

[PCR determination of an association between class II HLA and pemphigus vulgaris].

1999 • 12 citations

Autoantibodies against Cell Adhesion Molecules in Pemphigus

1994 • 10 citations

[Association between HLA-DRB1, DQB1 genes and pemphigus vulgaris in Chinese Hans].

2003 • 8 citations

Correlation between Profile of Circulating Mononuclear Cells and Clinical Manifestations in Patients with Pemphigus Vulgaris

2000 • 5 citations

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