Invariant chain — a regulator of antigen presentation

Antigen Recognition by Class I-Restricted T Lymphocytes

1989 • 1,207 citations

A hypothetical model of the foreign antigen binding site of Class II histocompatibility molecules

1988 • 1,161 citations

The Basis for the Immunoregulatory Role of Macrophages and Other Accessory Cells

1987 • 1,040 citations

Association of class I major histocompatibility heavy and light chains induced by viral peptides

1989 • 995 citations

BIOSYNTHETIC PROTEIN TRANSPORT AND SORTING BY THE ENDOPLASMIC RETICULUM AND GOLGI

1987 • 985 citations

Empty MHC class I molecules come out in the cold

1990 • 933 citations

Identification of a consensus motif for retention of transmembrane proteins in the endoplasmic reticulum.

1990 • 918 citations

Interaction between CD4 and class II MHC molecules mediates cell adhesion

1987 • 823 citations

The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation

1991 • 687 citations

Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments

1991 • 663 citations

MHC class II-associated invariant chain contains a sorting signal for endosomal compartments

1990 • 565 citations

Intracellular transport of class II MHC molecules directed by invariant chain

1990 • 548 citations

Immunology: The ins and outs of antigen processing and presentations

1986 • 498 citations

Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding

1990 • 486 citations

Co-localization of molecules involved in antigen processing and presentation in an early endocytic compartment

1990 • 377 citations

Membrane insertion and oligomeric assembly of HLA-DR histocompatibility antigens

1982 • 308 citations

Invariant chain distinguishes between the exogenous and endogenous antigen presentation pathways

1990 • 303 citations

Liposome-encapsulated antigens are processed in lysosomes, recycled, and presented to T cells

1991 • 250 citations

Detection of a common polypeptide chain in I-A and I-E sub-region immunoprecipitates

1979 • 217 citations

Invariant chain trimers are sequestered in the rough endoplasmic reticulum in the absence of association with HLA class II antigens.

1990 • 149 citations

Evidence for a continual exchange of 5′-nucleotidase between the cell surface and cytoplasmic membranes in cultured rat fibroblasts

1982 • 147 citations

Two forms of the la antigen-associated invariant chain result from alternative initiations at two in-phase AUGs

1986 • 124 citations

Chloroquine affects biosynthesis of Ia molecules by inhibiting dissociation of invariant (gamma) chains from alpha-beta dimers in B cells.

1985 • 123 citations

Intracellular traffic and antigen processing

1989 • 92 citations

Four Ia invariant chain forms derive from a single gene by alternate splicing and alternate initiation of transcription/translation.

1987 • 85 citations

Evidence for specific association between class I major histocompatibility antigens and the CD8 molecules of human suppressor/cytotoxic cells

1988 • 72 citations

Biosynthetic intermediates of HLA class II antigens from B lymphoblastoid cell lines.

1986 • 16 citations