Co-localization of molecules involved in antigen processing and presentation in an early endocytic compartment

Structure of the human class I histocompatibility antigen, HLA-A2

1987 • 3,453 citations

Handbook of Experimental Immunology.

1968 • 2,480 citations

ACIDIFICATION OF THE ENDOCYTIC AND EXOCYTIC PATHWAYS

1986 • 1,977 citations

Antigen-specific interaction between T and B cells

1985 • 1,396 citations

Antigen Recognition by Class I-Restricted T Lymphocytes

1989 • 1,207 citations

pH and the recycling of transferrin during receptor-mediated endocytosis.

1983 • 1,165 citations

Antigen-Presenting Function of the Macrophage

1984 • 1,164 citations

Two populations of Ia-like molecules on a human B cell line.

1980 • 1,112 citations

Association of class I major histocompatibility heavy and light chains induced by viral peptides

1989 • 995 citations

Handbook of experimental immunology

1987 • 680 citations

Decrease in macrophage antigen catabolism caused by ammonia and chloroquine is associated with inhibition of antigen presentation to T cells.

1982 • 576 citations

Immunology: The ins and outs of antigen processing and presentations

1986 • 498 citations

Isolation and characterization of antigen-la complexes involved in T cell recognition

1986 • 470 citations

Role for intracellular proteases in the processing and transport of class II HLA antigens.

1988 • 336 citations

Brefeldin A Specifically Inhibits Presentation of Protein Antigens to Cytotoxic T Lymphocytes

1989 • 329 citations

Antigen Presentation Pathways to Class I and Class II MHC‐Restricted T Lymphocytes

1987 • 322 citations

Brefeldin A implicates egress from endoplasmic reticulum in class I restricted antigen presentation

1989 • 317 citations

Role of coated vesicles, microfilaments, and calmodulin in receptor-mediated endocytosis by cultured B lymphoblastoid cells.

1980 • 315 citations

A simple post-embedding system for the rapid demonstration of tissue antigens under the electron microscope

1983 • 299 citations

Cathepsin D is membrane-associated in macrophage endosomes.

1988 • 259 citations

Ligands internalized through coated or noncoated invaginations follow a common intracellular pathway.

1987 • 254 citations

Visualization of acidic organelles in intact cells by electron microscopy.

1984 • 250 citations

HLA class II-restricted presentation of cytoplasmic measles virus antigens to cytotoxic T cells

1989 • 201 citations

Human cell-surface glycoprotein with unusual properties

1980 • 201 citations

Towards a better definition of human leucocyte surface molecules

1989 • 198 citations

Endocytosis and recycling of the T3-T cell receptor complex. The role of T3 phosphorylation.

1987 • 185 citations

A role of la-associated invariant chains in antigen processing and pressentation

1989 • 184 citations

Human T cell response to the surface antigen of hepatitis B virus (HBsAg). Endosomal and nonendosomal processing pathways are accessible to both endogenous and exogenous antigen.

1988 • 180 citations

Epitope-directed processing of specific antigen by B lymphocytes.

1989 • 163 citations

Direct binding of influenza peptides to class I HLA molecules

1989 • 149 citations

A role for the cytoplasmic domain in transferrin receptor sorting and coated pit formation during endocytosis

1988 • 140 citations

Intracellular class II HLA antigens are accessible to transferrin-neuraminidase conjugates internalized by receptor-mediated endocytosis.

1985 • 135 citations

Kinetics and temperature dependence of exposure of endocytosed material to proteolytic enzymes and low pH: Evidence for a maturation model for the formation of lysosomes

1987 • 126 citations

[43] Cathepsin D from porcine and bovine spleen

1981 • 124 citations

Chloroquine affects biosynthesis of Ia molecules by inhibiting dissociation of invariant (gamma) chains from alpha-beta dimers in B cells.

1985 • 123 citations

Antigen processing and intracellular Ia. Possible roles of endocytosis and protein synthesis in Ia function.

1989 • 122 citations

Antigen‐Presenting Function of B Lymphocytes

1988 • 121 citations

Clathrin structure characterized with monoclonal antibodies. I. Analysis of multiple antigenic sites.

1985 • 117 citations

100-kDa polypeptides in peripheral clathrin-coated vesicles are required for receptor-mediated endocytosis.

1989 • 110 citations

PROLIFERATION AND DIFFERENTIATION OF LYMPHOID CELLS: STUDIES WITH HUMAN LYMPHOID CELL LINES AND IMMUNOGLOBULIN SYNTHESIS

1971 • 108 citations

Antigen Processing for Presentation to T Lymphocytes: Function, Mechanisms, and Implications for the T-Cell Repertoire

1988 • 105 citations

Intracellular traffic and antigen processing

1989 • 92 citations

Monensin prevents terminal glycosylation of the N- and O-linked oligosaccharides of the HLA-DR-associated invariant chain and inhibits its dissociation from the alpha-beta chain complex.

1984 • 90 citations

Endocytosis and recycling of specific antigen by human B cell lines.

1988 • 89 citations

Turnover of Ia-peptide complexes is facilitated in viable antigen-presenting cells: biosynthetic turnover of Ia vs. peptide exchange.

1989 • 87 citations

Analysis of HLA-DR antigens by using monoclonal antibodies: recognition of conformational differences in biosynthetic intermediates.

1981 • 87 citations

Histochemical localization of cathepsin B at the invasion front of the rabbit V2 carcinoma.

1981 • 78 citations

Intracellular processing of epidermal growth factor and its effect on ligand-receptor interactions.

1985 • 71 citations

Evidence That the Gonadotrophs Are the Likely Site of Production of Angiotensin II in the Anterior Pituitary of the Rat*

1986 • 69 citations

Inhibition by leupeptin and antipain of the intracellular proteolysis of Ii

1989 • 66 citations

Plasma Membrane-Associated Cysteine Proteinases in Human and Animal Tumors

1987 • 65 citations

Efficiency of antigen presentation after antigen targeting to surface IgD, IgM, MHC, Fc gamma RII, and B220 molecules on murine splenic B cells.

1989 • 60 citations

The Biochemistry and Cell Biology of Antigen Processing

1988 • 59 citations

Diminished antigen processing by endosomal acidification mutant antigen-presenting cells.

1989 • 50 citations

Biophysical Aspects of Antigen Recognition by T Cells

1987 • 44 citations

Time Course of Intracellular Associations, Processing, and Cleavages of Ii Forms and Class II Major Histocompatibility Complex Molecules

1989 • 39 citations

Brain clathrin: immunofluorescent patterns in cultured cells and tissues.

1980 • 36 citations

Antigen-induced changes in phospholipid metabolism in antigen-binding B lymphocytes.

1987 • 34 citations

A profitable lesson in heresy

1989 • 30 citations

Internalized membrane immunoglobulin meets intracytoplasmic DR antigen in human B lymphoblastoid cells

1983 • 27 citations

Cell Biology of the Major Histocompatibility Complex

1985 • 27 citations

Processing of Immunoglobulin-associated Antigen in B Lymphocytes

1989 • 24 citations

Proteolytic Processing in Endosomal Vesicles

1989 • 17 citations

A fine structural analysis of the myelin sheath in rat spinal roots

1979 • 12 citations

Structural and Functional Aspects of HLA Class II Glycoproteins and the Associated Invariant Chain

1989 • 8 citations

Manipulation of Glycans on Antigens of the Major Histocompatibility Complex

1985 • 7 citations