Four Ia invariant chain forms derive from a single gene by alternate splicing and alternate initiation of transcription/translation.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

A Film Detection Method for Tritium‐Labelled Proteins and Nucleic Acids in Polyacrylamide Gels

1974 • 8,693 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

Rapid and Sensitive Protein Similarity Searches

1985 • 4,091 citations

High resolution two-dimensional electrophoresis of basic as well as acidic proteins

1977 • 3,556 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

SV40-transformed simian cells support the replication of early SV40 mutants

1981 • 2,564 citations

Why genes in pieces?

1978 • 2,256 citations

A cDNA cloning vector that permits expression of cDNA inserts in mammalian cells.

1983 • 933 citations

Tissue-specific generation of two preprotachykinin mRNAs from one gene by alternative RNA splicing

1984 • 563 citations

EUKARYOTIC PROTEIN SYNTHESIS

1985 • 538 citations

Point mutations close to the AUG initiator codon affect the efficiency of translation of rat preproinsulin in vivo

1984 • 520 citations

Identification of regulatory sequences in the prelude sequences of an H2A histone gene by the study of specific deletion mutants in vivo.

1980 • 471 citations

Intricate combinatorial patterns of exon splicing generate multiple regulated troponin T isoforms from a single gene

1985 • 314 citations

Membrane insertion and oligomeric assembly of HLA-DR histocompatibility antigens

1982 • 308 citations

Sendai virus contains overlapping genes expressed from a single mRNA

1983 • 231 citations

Detection of a common polypeptide chain in I-A and I-E sub-region immunoprecipitates

1979 • 217 citations

Experimental Manipulation of Gene Expression

1983 • 213 citations

Termination-reinitiation occurs in the translation of mammalian cell mRNAs.

1986 • 213 citations

Specific in vitro transcription of conalbumin gene is drastically decreased by single-point mutation in T-A-T-A box homology sequence.

1980 • 195 citations

The genealogy of some recently evolved vertebrate proteins

1985 • 179 citations

cDNA clone for the human invariant gamma chain of class II histocompatibility antigens and its implications for the protein structure.

1983 • 166 citations

Messenger rna for the ad2 dna binding protein: dna sequences encoding the first leader and heterogeneity at the mRNA 5′ end

1979 • 166 citations

Effect of upstream reading frames on translation efficiency in simian virus 40 recombinants.

1986 • 125 citations

The complete sequence of the mRNA for the HLA-DR-associated invariant chain reveals a polypeptide with an unusual transmembrane polarity.

1984 • 124 citations

Two forms of the la antigen-associated invariant chain result from alternative initiations at two in-phase AUGs

1986 • 124 citations

A human Ia cytoplasmic determinant located on multiple forms of invariant chain (gamma, gamma 2, gamma 3).

1984 • 119 citations

Structure, Function, and Genetics of Human Class II Molecules

1985 • 116 citations

Termination-Reinitiation Occurs in the Translation of Mammalian Cell mRNAs

1986 • 109 citations

Two‐dimensional gel analysis of the polypeptides precipitated by a polymorphic HLA‐DR1,2,w6 monoclonal antibody: Evidence for a third locus

1982 • 102 citations

Developmental variations in the splicing pattern of transcripts from the Drosophila gene encoding myosin alkali light chain result in different carboxyl-terminal amino acid sequences.

1985 • 101 citations

Effect of Upstream Reading Frames on Translation Efficiency in Simian Virus 40 Recombinants

1986 • 66 citations

Generation of Class II Antigen Polymorphism

1985 • 56 citations

Structure of the human Ia-associated invariant (gamma)-chain gene: identification of 5' sequences shared with major histocompatibility complex class II genes.

1986 • 46 citations

The gene encoding the human class II antigen-associated ? chain is located on chromosome 5

1984 • 46 citations

The human invariant chain is the core protein of the human class II-associated proteoglycan.

1986 • 42 citations

Structure of the human gene encoding the invariant γ-chain of class II histocompatibility antigens

1985 • 34 citations

Sequence of the 5′‐end quarter of the human‐thyroglobulin messenger ribonucleic acid and of its deduced amino‐acid sequence

1985 • 29 citations

Eukaryotic Protein Synthesis

1985 • 26 citations

RNA processing: Lessons from mutant globins

1983 • 25 citations