Human cathepsin W, a putative cysteine protease predominantly expressed in CD8⁺ T‐lymphocytes

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1986 • 4,785 citations

A new method for predicting signal sequence cleavage sites

1986 • 4,629 citations

Pycnodysostosis, a Lysosomal Disease Caused by Cathepsin K Deficiency

1996 • 1,003 citations

Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B

1995 • 720 citations

Cathepsin K, but Not Cathepsins B, L, or S, Is Abundantly Expressed in Human Osteoclasts

1996 • 706 citations

Essential Role for Cathepsin S in MHC Class II–Associated Invariant Chain Processing and Peptide Loading

1996 • 523 citations

Human Cathepsin O2, a Matrix Protein-degrading Cysteine Protease Expressed in Osteoclasts

1996 • 427 citations

Granzymes: exogenous porteinases that induce target cell apoptosis

1995 • 403 citations

Alignment/Phylogeny of the Papain Superfamily of Cysteine Proteases

1995 • 387 citations

Molecular Cloning of Human cDNA for Cathepsin K: Novel Cysteine Proteinase Predominantly Expressed in Bone

1995 • 357 citations

Two distinct gene subfamilies within the family of cysteine protease genes.

1993 • 354 citations

Molecular cloning of a possible cysteine proteinase predominantly expressed in osteoclasts.

1994 • 340 citations

A role for the ubiquitin-dependent proteolytic pathway in MHC class l-restricted antigen presentation

1993 • 317 citations

The Binding and Lysis of Target Cells by Cytotoxic Lymphocytes: Molecular and Cellular Aspects

1994 • 312 citations

Molecular cloning and expression of human alveolar macrophage cathepsin S, an elastinolytic cysteine protease.

1992 • 304 citations

Nucleotide and predicted amino acid sequences of cloned human and mouse preprocathepsin B cDNAs.

1986 • 245 citations

Human Cathepsin O2, a Novel Cysteine Protease Highly Expressed in Osteoclastomas and Ovary Molecular Cloning, Sequencing and Tissue Distribution

1995 • 241 citations

Cathepsin S from bovine spleen. Purification, distribution, intracellular localization and action on proteins

1989 • 211 citations

Molecular cloning of human cathepsin O, a novel endoproteinase and homologue of rabbit OC2

1995 • 167 citations

Complete nucleotide and deduced amino acid sequences of human and murine preprocathepsin L. An abundant transcript induced by transformation of fibroblasts.

1988 • 133 citations

Cloning and complete coding sequence of a novel human cathepsin expressed in giant cells of osteoclastomas

1995 • 112 citations

Inhibition of p38 Mitogen-activated Protein Kinase by Insulin in Cultured Fetal Neurons

1996 • 109 citations

Pathways for the processing and presentation of antigens to T cells

1995 • 89 citations

Participation of cathepsin B in processing of antigen presentation to MHC class II

1993 • 87 citations

The Role of Thiol Proteases in Tissue Injury and Remodeling

1994 • 87 citations

Human cathepsin O. Molecular cloning from a breast carcinoma, production of the active enzyme in Escherichia coli, and expression analysis in human tissues.

1994 • 87 citations

Phylogenetic conservation of cysteine proteinases. Cloning and expression of a cDNA coding for human cathepsin S.

1992 • 77 citations

Expression of Human Recombinant Granzyme A Zymogen and Its Activation by the Cysteine Proteinase Cathepsin C

1996 • 70 citations

Isolation and Characterization of Four Developmentally Regulated Cathepsin B-Like Cysteine Protease Genes from the Nematode Caenorhabditis elegans

1996 • 57 citations

Nucleotide sequence of human preprocathepsin H, a lysosomal cysteine proteinase

1989 • 38 citations

Mechanism and regulation of antigen processing by cathepsin B

1994 • 24 citations

Identification of Two Novel Dictyostelium discoideum Cysteine Proteinases That Carry N-Acetylglucosamine-1-P Modification

1995 • 24 citations

Evidence supporting a role for cathepsin B in the generation of T cell antigenic epitopes of human growth hormone

1993 • 12 citations

Structure and Possible Functions of Lymphocyte Granzymes

1993 • 6 citations