Blocking of EGF-Dependent Cell Proliferation by EGF Receptor Kinase Inhibitors

The determination of enzyme inhibitor constants

1953 • 4,050 citations

Genistein, a specific inhibitor of tyrosine-specific protein kinases.

1987 • 3,773 citations

RECEPTORS FOR EPIDERMAL GROWTH FACTOR AND OTHER POLYPEPTIDE MITOGENS

1987 • 1,274 citations

Insulin Stimulates the Phosphorylation of the 95,000-Dalton Subunit of Its Own Receptor

1982 • 1,138 citations

After Insulin Binds

1987 • 687 citations

Stimulation of tyrosine-specific phosphorylation by platelet-derived growth factor

1982 • 675 citations

Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor

1987 • 609 citations

Self-phosphorylation of epidermal growth factor receptor: evidence for a model of intermolecular allosteric activation

1987 • 508 citations

Stimulation and inhibition of growth by EGF in different A431 cell clones is accompanied by the rapid induction of c-fos and c-myc proto-oncogenes.

1985 • 257 citations

Synthetic tyrosine polymers as substrates and inhibitors of tyrosine-specific protein kinases.

1984 • 246 citations

Studies on a new epidermal growth factor-receptor kinase inhibitor, erbstatin, produced by MH435-hF3.

1986 • 214 citations

A mutant epidermal growth factor receptor with defective protein tyrosine kinase is unable to stimulate proto-oncogene expression and DNA synthesis.

1987 • 186 citations

The effect of quercetin on the phosphorylatio activity of the Rous sarcoma virus transforming gene product in vitro and in vivo

1983 • 177 citations

A chimaeric receptor allows insulin to stimulate tyrosine kinase activity of epidermal growth factor receptor

1986 • 160 citations

Subversion of growth regulatory pathways in malignant transformation

1987 • 84 citations

Quercetin inhibits tyrosine phosphorylation by the cyclic nucleotide-independent, transforming protein kinase, pp60src

1981 • 70 citations

A nonmitogenic analogue of epidermal growth factor induces early responses mediated by epidermal growth factor.

1982 • 64 citations