Epidermal growth factor—induced actin remodeling is regulated by 5-lipoxygenase and cyclooxygenase products

Signal transduction by receptors with tyrosine kinase activity

1990 • 5,528 citations

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1992 • 4,454 citations

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1992 • 3,628 citations

cPLA2 is phosphorylated and activated by MAP kinase

1993 • 1,858 citations

RECEPTORS FOR EPIDERMAL GROWTH FACTOR AND OTHER POLYPEPTIDE MITOGENS

1987 • 1,274 citations

Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis

1990 • 777 citations

Increase of the Catalytic Activity of Phospholipase C-γ1 by Tyrosine Phosphorylation

1990 • 650 citations

Cytosolic phospholipase A2 is coupled to hormonally regulated release of arachidonic acid.

1992 • 546 citations

Identification and isolation of a membrane protein necessary for leukotriene production

1990 • 464 citations

From signal to pseudopod

1989 • 460 citations

Signal transduction by allosteric receptor oligomerization

1988 • 410 citations

Rapid phosphorylation and reorganization of ezrin and spectrin accompany morphological changes induced in A-431 cells by epidermal growth factor.

1989 • 385 citations

L-663,536 (MK-886) (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor

1989 • 337 citations

Rapid induction of morphological changes in human carcinoma cells A-431 by epidermal growth factors.

1979 • 300 citations

The epidermal growth factor-induced calcium signal in A431 cells.

1986 • 297 citations

The Effect of GTPase Activating Protein Upon Ras Is Inhibited by Mitogenically Responsive Lipids

1989 • 287 citations

Signal transduction and invasion of epithelial cells by S. typhimurium

1993 • 260 citations

Epidermal growth factor stimulates the production of phosphatidylinositol monophosphate and the breakdown of polyphosphoinositides in A431 cells.

1987 • 230 citations

A point mutation at the ATP-binding site of the EGF-receptor abolishes signal transduction.

1988 • 215 citations

Epidermal growth factor activates calcium channels by phospholipase A25-lipoxygenase-mediated leukotriene C4 production

1992 • 179 citations

Eicosanoid-mediated contractility of hepatic stellate cells

1992 • 161 citations

A Cytoplasmic Protein Inhibits the GTPase Activity of H-Ras in a Phospholipid-Dependent Manner

1990 • 153 citations

Epidermal growth factor induces redistribution of actin and α-actinin in human epidermal carcinoma cells

1981 • 139 citations

Modulation of the epidermal growth factor mitogenic response by metabolites of linoleic and arachidonic acid in Syrian hamster embryo fibroblasts. Differential effects in tumor suppressor gene (+) and (-) phenotypes.

1992 • 133 citations

Epidermal growth factor induces rapid reorganization of the actin microfilament system in human A431 cells

1991 • 130 citations

Mitogenic signaling by epidermal growth factor (EGF), but not platelet-derived growth factor, requires arachidonic acid metabolism in BALB/c 3T3 cells. Modulation of EGF-dependent c-myc expression by prostaglandins.

1990 • 130 citations

Endogenous non-cyclooxygenase metabolites of arachidonic acid modulate growth and mRNA levels of immediate-early response genes in rat mesangial cells

1991 • 122 citations

Actin assembly in electropermeabilized neutrophils: role of intracellular calcium.

1990 • 119 citations

Thrombin signal transduction mechanisms in rat vascular smooth muscle cells. Calcium and protein kinase C-dependent and -independent pathways.

1990 • 115 citations

Three classes of epidermal growth factor receptors on HeLa cells.

1991 • 101 citations

Regulation of Ras-GAP and the Neurofibromatosis-1 Gene Product by Eicosanoids

1991 • 100 citations

Epidermal growth factor-activated calcium and potassium channels.

1991 • 97 citations

Antibody-induced dimerization activates the epidermal growth factor receptor tyrosine kinase

1991 • 96 citations

A negative feedback loop attenuates EGF-induced morphological changes.

1991 • 82 citations

The Dissociation of the Phalloidin-Actin Complex

1977 • 77 citations

The GTPase stimulatory activities of the neurofibromatosis type 1 and the yeast IRA2 proteins are inhibited by arachidonic acid.

1991 • 69 citations

Inhibition by phospholipids of the interaction between R-ras, rho, and their GTPase-activating proteins.

1989 • 66 citations

Serum stimulation of NIH 3T3 cells induces the production of lipids able to inhibit GTPase-activating protein activity.

1990 • 66 citations

Lack of correlation between changes in polyphosphoinositide levels and actin/gelsolin complexes in A431 cells treated with epidermal growth factor.

1991 • 58 citations

Characterization and identification of an epidermal-growth-factor-activated phospholipase A2

1992 • 58 citations

Epidermal-growth-factor-induced formation of inositol phosphates in human A431 cells. Differences from the effect of bradykinin

1988 • 57 citations

Ras GTPase-activating protein physically associates with mitogenically active phospholipids.

1991 • 56 citations

Phosphatidylinositol kinase is activated in membranes derived from cells treated with epidermal growth factor.

1987 • 53 citations

Characterization of tetramethylrhodaminyl‐phalloidin binding to cellular F‐actin

1992 • 51 citations

Modulation of phospholipase A2 activity by epidermal growth factor (EGF) in CHO cells transfected with human EGF receptor. Role of receptor cytoplasmic subdomain

1991 • 37 citations

Prostaglandins: Biology and chemistry of prostaglandins and related eicosanoids

1988 • 27 citations

Deleted Work

1955 • 0 citations