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Effect of chemically well-defined sphingosine and its N-methyl derivatives on protein kinase C and src kinase activities

Data up to Jan 2025

Published1989
Citations259
References25

Total Citations Per Year

Abstract

References (25)

Phorbol esters increase the amount of Ca2+, phospholipid-dependent protein kinase associated with plasma membrane

1983 • 1,304 citations

Functions of Sphingolipids and Sphingolipid Breakdown Products in Cellular Regulation

1989 • 1,251 citations

Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets.

1986 • 1,150 citations

Reductive alkylation of amino groups in proteins

1968 • 678 citations

Lysosphingolipids Inhibit Protein Kinase C: Implications for the Sphingolipidoses

1987 • 593 citations

Methods for methanolysis of sphingolipids and direct determination of long‐chain bases by gas chromatography

1965 • 533 citations

Regulation of protein kinase C activity by gangliosides.

1987 • 248 citations

Structural requirements for long-chain (sphingoid) base inhibition of protein kinase C in vitro and for the cellular effects of these compounds

1989 • 247 citations

Synthetic tyrosine polymers as substrates and inhibitors of tyrosine-specific protein kinases.

1984 • 246 citations

Isolation and characterization of two distinct forms of protein kinase C.

1987 • 192 citations

Purification and characterization of three types of protein kinase C from rabbit brain cytosol.

1987 • 168 citations

Regulation of the epidermal growth factor receptor phosphorylation state by sphingosine in A431 human epidermoid carcinoma cells.

1988 • 151 citations

Modulation of the free sphingosine levels in human neutrophils by phorbol esters and other factors.

1988 • 97 citations

Lipid components of gangliosides

1964 • 97 citations

Two alternative mechanisms control the interconversion of functional states of the epidermal growth factor receptor.

1988 • 93 citations

Activation of the epidermal growth factor receptor tyrosine protein kinase in the absence of receptor oligomerization.

1988 • 84 citations

A highly stereoselective synthesis of 2(S), 3(R), 4E- and 2(S), 3(R), 4Z-N-tetracosanoylsphingenine from d-glucose

1986 • 45 citations

An efficient synthesis of ceramide fromd-glucose

1984 • 44 citations

Nomenclature of Organic Compounds

1974 • 41 citations

Nomenclature of organic compounds

1974 • 24 citations

Partial Identity of Sphingosine Methyl Ethers*

1964 • 23 citations

Selective synthesis of cerebrosides: (2S, 3R, 4E)-1-O-?-d-galactopyranosyl-N-(2?R and 2?S)-2?-hydroxytetracosanoyl-sphingenine

1985 • 22 citations

Chemical Properties and Stereoisomerism of Heterogeneous Long Chain Bases in Lysosphingolipids by Positive Ion Fast Atom Bombardment Mass Spectrometry and Carbon-13 NMR Spectroscopy1

1986 • 20 citations

Brain protein kinase C phosphorylating poly(arginine,serine) or lamin B is stimulated by anions and by an activator purified from bovine serum albumin preparations.

1989 • 15 citations

Chemical and Immunological Characterization of Caprine Erythrocyte Glycolipids in Comparison with Porcine Erythrocyte Glycolipids

1972 • 12 citations

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Effect of chemically well-defined sphingosine and its N-methyl derivatives on protein… (1989) – Biochemistry | Metascience Observatory Explorer