Modulation of the free sphingosine levels in human neutrophils by phorbol esters and other factors.

Oxidatively modified low density lipoproteins: a potential role in recruitment and retention of monocyte/macrophages during atherogenesis.

1987 • 1,152 citations

Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets.

1986 • 1,150 citations

Complement and immunoglobulins stimulate superoxide production by human leukocytes independently of phagocytosis.

1975 • 749 citations

A Potential Second Messenger Role for Unsaturated Fatty Acids: Activation of Ca ²⁺ -Dependent Protein Kinase

1984 • 618 citations

Monocytes and Neutrophils Oxidize Low Density Lipoprotein Making It Cytotoxic

1985 • 536 citations

Phagocytes as Carcinogens: Malignant Transformation Produced by Human Neutrophils

1985 • 443 citations

Biological Defense Mechanisms THE EFFECT OF BACTERIA AND SERUM ON SUPEROXIDE PRODUCTION BY GRANULOCYTES

1974 • 309 citations

Inhibition of phorbol ester-dependent differentiation of human promyelocytic leukemic (HL-60) cells by sphinganine and other long-chain bases.

1986 • 307 citations

Inhibition of the oxidative burst in human neutrophils by sphingoid long-chain bases. Role of protein kinase C in activation of the burst.

1986 • 294 citations

A simple and novel method for tritium labeling of gangliosides and other sphingolipids

1978 • 250 citations

1,2-Diacylglycerols but not phorbol esters stimulate sphingomyelin hydrolysis in GH3 pituitary cells.

1987 • 211 citations

Sphingosine inhibition of agonist-dependent secretion and activation of human platelets implies that protein kinase C is a necessary and common event of the signal transduction pathways.

1987 • 156 citations

Structures of glycosphingolipids isolated from human granulocytes. The presence of a series of linear poly-N-acetyllactosaminylceramide and its significance in glycolipids of whole blood cells.

1985 • 156 citations

Biosynthesis of long-chain (sphingoid) bases from serine by LM cells. Evidence for introduction of the 4-trans-double bond after de novo biosynthesis of N-acylsphinganine(s).

1986 • 145 citations

Protein kinase C activity appears to be required for the synthesis of platelet-activating factor and leukotriene B4 by human neutrophils.

1987 • 140 citations

Cytochalasin B enhancement of the diacylglycerol response in formyl peptide-stimulated neutrophils.

1986 • 133 citations

Sphinganine effects on chemoattractant-induced diacylglycerol generation, calcium fluxes, superoxide production, and on cell viability in the human neutrophil. Delivery of sphinganine with bovine serum albumin minimizes cytotoxicity without affecting inhibition of the respiratory burst.

1988 • 119 citations

TOXICITY OF CADMIUM.

1964 • 110 citations

Radiation-like modification of bases in DNA exposed to tumor promoter-activated polymorphonuclear leukocytes.

1986 • 106 citations

Diastereoselective synthesis of unsaturated vicinal amino alcohols via Diels-Alder reactions of N-sulfinyl dienophiles

1984 • 80 citations

The fatty acid composition of phosphatidylinositol, phosphatidate and 1,2-diacylglycerol in stimulated human neutrophils

1984 • 80 citations

INCREASED LEUCOCYTE OXIDATIVE METABOLISM IN HYPERLIPOPROTEINAEMIA

1982 • 68 citations

Acid and alkaline ceramidases of rat tissues

1986 • 57 citations

Sphingolipids inhibit insulin and phorbol ester stimulated uptake of 2-deoxyglucose

1986 • 50 citations

Protein kinase C inhibition by sphingoid long-chain bases: Effects on secretion in human neutrophils

1987 • 42 citations

Regulation of mitochondrial compartment volumes in rat adrenal cortex by ether stress

1985 • 42 citations

In vitro proteolysis of human plasma low density lipoproteins by an elastase released from human blood polymorphonuclear cells.

1986 • 39 citations

Separation of Sphingosine and Dihydrosphingosine by Reversed Phase Paper Chromatography

1960 • 38 citations

A convenient spectrophotometric method for the kinetic analysis of the enzymatic hydrolysis of N-acyl peptides using phthaldialdehyde

1981 • 21 citations

Stimulation of glycolipid synthesis and exchange by human serum high density lipoprotein-3 in human fibroblasts and leukocytes.

1981 • 20 citations

Phorbol ester-associated changes in ganglioside metabolism

1983 • 19 citations

Retention of gangliosides in serum delipidated by diisopropyl ether-1-butanol extraction.

1983 • 16 citations

Reversible exchange of glycosphingolipids between human high and low density lipoproteins.

1982 • 16 citations

Influence of phagocyte-derived active oxygen species in tissue responses to tumour promoters and irritants

1986 • 5 citations

Enhancement of formyl-methionyl-leucyl-phenylalanine-induced directional locomotion of human neutrophils by serum low-density lipoproteins

1982 • 1 citations