Interactions between dorsal and helix-loop-helix proteins initiate the differentiation of the embryonic mesoderm and neuroectoderm in Drosophila.

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1988 • 6,107 citations

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1989 • 2,706 citations

A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback

1989 • 2,555 citations

Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase

1991 • 1,779 citations

The origin of pattern and polarity in the Drosophila embryo

1992 • 1,367 citations

A gradient of nuclear localization of the dorsal protein determines dorsoventral pattern in the Drosophila embryo

1989 • 652 citations

twist and snail as positive and negative regulators during Drosophila mesoderm development.

1991 • 550 citations

The achaete-scute gene complex of D. melanogaster: Conserved Domains in a subset of genes required for neurogenesis and their homology to myc

1987 • 501 citations

Dorsal , an Embryonic Polarity Gene in Drosophila , Is Homologous to the Vertebrate Proto-Oncogene, c- rel

1987 • 485 citations

The graded distribution of the dorsal morphogen is initiated by selective nuclear transport in Drosophila

1989 • 472 citations

Sequence of the twist gene and nuclear localization of its protein in endomesodermal cells of early Drosophila embryos.

1988 • 471 citations

Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations.

1992 • 461 citations

daughterless, a Drosophila gene essential for both neurogenesis and sex determination, has sequence similarities to myc and the achaete-scute complex

1988 • 442 citations

Determination of spatial domains of zygotic gene expression in the Drosophila embryo by the affinity of binding sites for the bicoid morphogen

1989 • 432 citations

Relocalization of the dorsal protein from the cytoplasm to the nucleus correlates with its function

1989 • 431 citations

A lymphocyte-specific enhancer in the mouse immunoglobulin κ gene

1984 • 410 citations

rhomboid, a gene required for dorsoventral axis establishment and peripheral nervous system development in Drosophila melanogaster.

1990 • 389 citations

The dorsal morphogen gradient regulates the mesoderm determinant twist in early Drosophila embryos.

1991 • 361 citations

The Drosophila single-minded gene encodes a nuclear protein with sequence similarity to the per gene product

1988 • 353 citations

MATERNAL-ZYGOTIC GENE INTERACTIONS DURING FORMATION OF THE DORSOVENTRAL PATTERN IN DROSOPHILA EMBRYOS

1983 • 338 citations

The dorsal gradient morphogen regulates stripes of rhomboid expression in the presumptive neuroectoderm of the Drosophila embryo.

1992 • 324 citations

Binding affinities and cooperative interactions with bHLH activators delimit threshold responses to the dorsal gradient morphogen

1993 • 322 citations

The Drosophila developmental gene snail encodes a protein with nucleic acid binding fingers

1987 • 312 citations

dorsal-twist interactions establish snail expression in the presumptive mesoderm of the Drosophila embryo.

1992 • 309 citations

Molecular genetics of the achaete-scute gene complex of D. melanogaster

1985 • 287 citations

The expression of three members of the achaete-scute gene complex correlates with neuroblast segregation in Drosophila

1987 • 272 citations

The Drosophila extramacrochaetae protein antagonizes sequence-specific DNA binding by daughterless/achaete-scute protein complexes

1991 • 257 citations

Molecular genetics of the single-minded locus: A gene involved in the development of the Drosophila nervous system

1988 • 254 citations

Establishment of the Mesoderm-Neuroectoderm Boundary in the Drosophila Embryo

1991 • 241 citations

Transcriptional activation by heterodimers of the achaete-scute and daughterless gene products of Drosophila.

1991 • 238 citations

Sequence-specific transactivation of the Drosophila twist gene by the dorsal gene product

1991 • 236 citations

The dorsal morphogen is a sequence-specific DNA-binding protein that interacts with a long-range repression element in drosophila

1991 • 229 citations

The maternal sex determination gene daughterless has zygotic activity necessary for the formation of peripheral neurons in Drosophila.

1988 • 179 citations

Molecular characterization of daughterless, a Drosophila sex determination gene with multiple roles in development.

1988 • 164 citations

Functional analysis of the Drosophila twist promoter reveals a dorsal-binding ventral activator region.

1991 • 132 citations

The achaete-scute complex is expressed in neurogenic regions of Drosophila embryos

1987 • 129 citations

Molecular analysis of the neurogenic locus Enhancer of split of Drosophila melanogaster

1987 • 119 citations

The affairs of daughterless and the promiscuity of developmental regulators

1989 • 97 citations

The daughterless gene product in Drosophila is a nuclear protein that is broadly expressed throughout the organism during development

1993 • 85 citations

The determination of sense organs in Drosophila: interaction of scute with daughterless

1988 • 71 citations

Neuroectoderm in Drosophila embryos is dependent on the mesoderm for positioning but not for formation.

1991 • 58 citations