G protein-coupled receptors GPR4 and TDAG8 are oncogenic and overexpressed in human cancers

Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a

1997 • 4,870 citations

G-protein-coupled receptors and signaling networks: emerging paradigms

2001 • 1,005 citations

Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation

2002 • 881 citations

G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator

1998 • 837 citations

Proton-sensing G-protein-coupled receptors

2003 • 667 citations

The cyclic AMP-mediated stimulation of cell proliferation

1989 • 464 citations

Ectopic Expression of the Serotonin 1c Receptor and the Triggering of Malignant Transformation

1989 • 355 citations

The hypoxic tumour microenvironment and metastatic progression.

2003 • 326 citations

G-protein-coupled receptor genes as protooncogenes: constitutively activating mutation of the alpha 1B-adrenergic receptor enhances mitogenesis and tumorigenicity.

1991 • 321 citations

Muscarinic acetylcholine receptor subtypes as agonist-dependent oncogenes.

1991 • 288 citations

Cell growth control by G protein-coupled receptors: from signal transduction to signal integration

1998 • 265 citations

Sphingosylphosphorylcholine and Lysophosphatidylcholine Are Ligands for the G Protein-coupled Receptor GPR4

2001 • 242 citations

The small GTP-binding protein Rho links G protein-coupled receptors and Gα ₁₂ to the serum response element and to cellular transformation

1997 • 211 citations

Distinct effects of cAMP and mitogenic signals on CREB-binding protein recruitment impart specificity to target gene activation via CREB

2001 • 189 citations

Rho Proteins and Cancer

2004 • 188 citations

Identification of a Molecular Target of Psychosine and Its Role in Globoid Cell Formation

2001 • 180 citations

Expression Cloning of Oncogenes by Retroviral Transfer of cDNA Libraries

1995 • 178 citations

Transforming G proteins

2001 • 146 citations

A DNA damage and stress inducible G protein-coupled receptor blocks cells in G₂/M

1998 • 144 citations

Novel GPCRs and their endogenous ligands: expanding the boundaries of physiology and pharmacology

1999 • 134 citations

Identification of a Putative G Protein-Coupled Receptor Induced during Activation-Induced Apoptosis of T Cells

1996 • 109 citations

Identification of Human OGR1, a Novel G Protein-Coupled Receptor That Maps to Chromosome 14

1996 • 98 citations

Isolation of Three Novel Human Genes Encoding G Protein-Coupled Receptors

1995 • 97 citations

G2A is an oncogenic G protein-coupled receptor

2000 • 78 citations

Mitogenic pathways regulated by G protein oncogenes.

1992 • 63 citations

Cloning, Characterization, and Mapping of Human Homolog of Mouse T-Cell Death-Associated Gene

1998 • 61 citations

Vacuolar H+-ATPase: functional mechanisms and potential as a target for cancer chemotherapy

2002 • 57 citations

Isolation of a Novel G Protein-Coupled Receptor (GPR4) Localized to Chromosome 19q13.3

1995 • 49 citations

Cloning, sequencing and tissue distribution of two related G protein‐coupled receptor candidates expressed prominently in human lung tissue

1995 • 35 citations