The role of phosphorylation and the CDC28 protein kinase in cell cycle-regulated nuclear import of the S. cerevisiae transcription factor SW15

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

A short amino acid sequence able to specify nuclear location

1984 • 2,529 citations

Transforming gene product of Rous sarcoma virus phosphorylates tyrosine

1980 • 2,387 citations

Fluorographic detection of radioactivity in polyacrylamide gols with the water-soluble fluor, sodium salicylate

1979 • 1,976 citations

Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence

1991 • 1,501 citations

[42] Detection and quantification of phosphotyrosine in proteins

1983 • 1,184 citations

Structural rearrangements of tubulin and actin during the cell cycle of the yeast Saccharomyces.

1984 • 827 citations

[21] β-Galactosidase gene fusions for analyzing gene expression in Escherichia coli and yeast

1983 • 783 citations

Saccharomyces cerevisiae cell cycle

1974 • 747 citations

mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2

1991 • 688 citations

Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src

1987 • 567 citations

A polypeptide domain that specifies migration of nucleoplasmin into the nucleus

1982 • 556 citations

How proteins enter the nucleus

1991 • 555 citations

Nuclear protein migration involves two steps: Rapid binding at the nuclear envelope followed by slower translocation through nuclear pores

1988 • 551 citations

Protein Import into the Cell Nucleus

1986 • 544 citations

Nuclear import can be separated into distinct steps in vitro: Nuclear pore binding and translocation

1988 • 535 citations

Synthetic peptides as nuclear localization signals

1986 • 472 citations

The role of CDC28 and cyclins during mitosis in the budding yeast S. cerevisiae

1991 • 463 citations

Five SWI genes are required for expression of the HO gene in yeast

1984 • 450 citations

Functions of microtubules in the Saccharomyces cerevisiae cell cycle.

1988 • 410 citations

THE SELECTION OF S. CEREVISIAE MUTANTS DEFECTIVE IN THE START EVENT OF CELL DIVISION

1980 • 391 citations

Protein kinase activity associated with the product of the yeast cell division cycle gene CDC28.

1985 • 370 citations

Nuclear and nucleolar targeting sequences of c-erb-A, c-myb, N-myc, p53, HSP70, and HIV tat proteins

1989 • 358 citations

Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2.

1990 • 353 citations

Reversible arrest of haploid yeast cells at the initiation of DNA synthesis by a diffusible sex factor

1973 • 352 citations

The rate of nuclear cytoplasmic protein transport is determined by the casein kinase II site flanking the nuclear localization sequence of the SV40 T-antigen.

1991 • 351 citations

Saccharomyces cerevisiae cell cycle.

1974 • 322 citations

Purified maturation promoting factor phosphorylates pp60c-src at the sites phosphorylated during fibroblast mitosis

1989 • 319 citations

[13] Immunochemical identification of membrane proteins after sodium dodecyl sulfate—polyacrylamide gel electrophoresis

1983 • 309 citations

Mammalian growth-associated H1 histone kinase: a homolog of cdc2+/CDC28 protein kinases controlling mitotic entry in yeast and frog cells.

1989 • 265 citations

Phosphorylation of large tumour antigen by cdc2 stimulates SV40 DNA replication

1989 • 242 citations

Assembly in vitro of nuclei active in nuclear protein transport: ATP is required for nucleoplasmin accumulation.

1986 • 235 citations

A bifunctional gene product involved in two phases of the yeast cell cycle

1982 • 225 citations

INTERCONVERSION OF YEAST MATING TYPES I. DIRECT OBSERVATIONS OF THE ACTION OF THE HOMOTHALLISM (HO) GENE

1976 • 225 citations

Isolation of human cDNA clones ofmyb-related genes, A-myband B-myb

1988 • 222 citations

The identification of a second cell cycle control on the HO promoter in yeast: Cell cycle regulation of SWI5 nuclear entry

1990 • 215 citations

Transcriptional Regulation in the Yeast Life Cycle

1987 • 196 citations

Spectrophotometric quantitation of silver grains eluted from autoradiograms

1983 • 195 citations

Both positive and negative regulators of HO transcription are required for mother-cell-specific mating-type switching in yeast

1987 • 171 citations

Chapter 4 Preparation of RNA and Ribosomes from Yeast

1975 • 171 citations

Characterization of a transcription factor involved in mother cell specific transcription of the yeast HO gene.

1988 • 147 citations

Synergistic Phosphorylation of Rabbit Muscle Glycogen Synthase by Cyclic AMP-dependent Protein Kinase and Casein Kinase I

1989 • 133 citations

At least 1400 base pairs of 5′-flanking DNA is required for the correct expression of the HO gene in yeast

1985 • 116 citations

Cytoplasmic anchoring proteins and the control of nuclear localization

1989 • 106 citations

DNA binding activity and transcriptional activator function of the human B-myb protein compared with c-MYB.

1990 • 105 citations

Cell cycle regulation of SW15 is required for mother-cell-specific HO transcription in yeast

1987 • 103 citations