DIRECT EVIDENCE FOR A ROLE OF β‐CATENIN/LEF‐1 SIGNALING PATHWAY IN INDUCTION OF EMT

Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC

1997 • 3,847 citations

The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression

2000 • 3,504 citations

Functional interaction of β-catenin with the transcription factor LEF-1

1996 • 2,847 citations

β-catenin is a target for the ubiquitin–proteasome pathway

1997 • 2,461 citations

An Overview of Epithelio-Mesenchymal Transformation

1995 • 1,505 citations

The Two-Handed E Box Binding Zinc Finger Protein SIP1 Downregulates E-Cadherin and Induces Invasion

2001 • 1,351 citations

Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

1998 • 1,097 citations

Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion.

1989 • 961 citations

Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene.

1993 • 912 citations

Nuclear localization of β-catenin by interaction with transcription factor LEF-1

1996 • 864 citations

An SV40-immortalized human corneal epithelial cell line and its characterization.

1995 • 714 citations

β-Catenin Regulates the Expression of the Matrix Metalloproteinase-7 in Human Colorectal Cancer

1999 • 665 citations

Siah-1, SIP, and Ebi Collaborate in a Novel Pathway for β-Catenin Degradation Linked to p53 Responses

2001 • 586 citations

Nuclear-cytoplasmic shuttling of APC regulates β-catenin subcellular localization and turnover

2000 • 472 citations

Interaction between Wnt and TGF-β signalling pathways during formation of Spemann's organizer

2000 • 467 citations

Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-β and Wnt pathways

2000 • 444 citations

Induction and regulation of epithelial–mesenchymal transitions

2000 • 434 citations

Cell adhesion and the integrin-linked kinase regulate the LEF-1 and β-catenin signaling pathways

1998 • 421 citations

Siah-1 Mediates a Novel β-Catenin Degradation Pathway Linking p53 to the Adenomatous Polyposis Coli Protein

2001 • 416 citations

β-Trcp couples β-catenin phosphorylation-degradation and regulates Xenopus axis formation

1999 • 385 citations

Modulation of Transcriptional Regulation by LEF-1 in Response to Wnt-1 Signaling and Association with β-Catenin

1998 • 366 citations

The Wnt/Wg Signal Transducer β-Catenin Controls Fibronectin Expression

1999 • 353 citations

The APC tumour suppressor has a nuclear export function

2000 • 348 citations

Plakoglobin and β-catenin: Protein interactions, regulation and biological roles

2000 • 334 citations

Activation of Both MAP Kinase and Phosphatidylinositide 3-Kinase by Ras Is Required for Hepatocyte Growth Factor/Scatter Factor–induced Adherens Junction Disassembly

1998 • 330 citations

Dissociation of Madin-Darby canine kidney epithelial cells by the monoclonal antibody anti-arc-1: mechanistic aspects and identification of the antigen as a component related to uvomorulin.

1985 • 286 citations

Epithelial-Mesenchymal Transitions in Cancer Progression

1996 • 271 citations

Inhibition of integrin linked kinase (ILK) suppresses β-catenin-Lef/Tcf-dependent transcription and expression of the E-cadherin repressor, snail, in APC−/− human colon carcinoma cells

2001 • 243 citations

NH2-terminal Deletion of β-Catenin Results in Stable Colocalization of Mutant β-Catenin with Adenomatous Polyposis Coli Protein and Altered MDCK Cell Adhesion

1997 • 220 citations

Epithelial Mesenchymal Transition by c-Fos Estrogen Receptor Activation Involves Nuclear Translocation of β-Catenin and Upregulation of β-Catenin/Lymphoid Enhancer Binding Factor-1 Transcriptional Activity

2000 • 207 citations

Overexpression of β-Catenin Induces Apoptosis Independent of Its Transactivation Function with LEF-1 or the Involvement of Major G1 Cell Cycle Regulators

2000 • 203 citations

Hot spots in beta-catenin for interactions with LEF-1, conductin and APC.

2000 • 194 citations

Cloning and Characterization of ThreeXenopus Slug Promoters Reveal Direct Regulation by Lef/β-Catenin Signaling

2001 • 163 citations

Wnt signalling: a theme with nuclear variations

2001 • 112 citations

Overexpression of the integrin-linked kinase mesenchymally transforms mammary epithelial cells

2001 • 108 citations

H-Ras Activation Promotes Cytoplasmic Accumulation and Phosphoinositide 3-Oh Kinase Association of β-Catenin in Epidermal Keratinocytes

1999 • 84 citations

Tissue-Specific Expression of β-Catenin in Normal Mesenchyme and Uveal Melanomas and Its Effect on Invasiveness

1998 • 42 citations