β-catenin is a target for the ubiquitin–proteasome pathway

Lessons from Hereditary Colorectal Cancer

1996 • 4,900 citations

Functional interaction of β-catenin with the transcription factor LEF-1

1996 • 2,847 citations

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

1994 • 2,480 citations

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

1985 • 2,456 citations

STRUCTURE AND FUNCTIONS OF THE 20S AND 26S PROTEASOMES

1996 • 2,408 citations

Production of high-titer helper-free retroviruses by transient transfection.

1993 • 2,280 citations

Improved retroviral vectors for gene transfer and expression.

1989 • 1,997 citations

XTcf-3 Transcription Factor Mediates β-Catenin-Induced Axis Formation in Xenopus Embryos

1996 • 1,827 citations

Inhibition of Proteasome Activities and Subunit-Specific Amino-Terminal Threonine Modification by Lactacystin

1995 • 1,601 citations

THE UBIQUITIN SYSTEM FOR PROTEIN DEGRADATION

1992 • 1,402 citations

The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species.

1989 • 1,393 citations

Binding of GSK3β to the APC-β-Catenin Complex and Regulation of Complex Assembly

1996 • 1,382 citations

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway.

1995 • 1,296 citations

The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3.

1996 • 1,156 citations

Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein.

1995 • 1,025 citations

From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion

1993 • 997 citations

Ubiquitin-dependent c-Jun degradation in vivo is mediated by the δ domain

1994 • 930 citations

Nuclear localization of β-catenin by interaction with transcription factor LEF-1

1996 • 864 citations

Isolation of Monoclonal Antibodies Specific for Human c-myc Proto-Oncogene Product

1985 • 788 citations

Mapping of the Inducible IκB Phosphorylation Sites That Signal Its Ubiquitination and Degradation†

1996 • 717 citations

Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor.

1994 • 712 citations

Signal transduction through beta-catenin and specification of cell fate during embryogenesis.

1996 • 663 citations

A Homolog of the armadillo Protein in Drosophila (Plakoglobin) Associated with E-Cadherin

1991 • 632 citations

THE UBIQUITIN-CONJUGATION SYSTEM

1992 • 561 citations

Assembly of the cadherin-catenin complex in vitro with recombinant proteins

1994 • 557 citations

Transmembrane control of cadherin-mediated cell adhesion: a 94 kDa protein functionally associated with a specific region of the cytoplasmic domain of E-cadherin.

1989 • 436 citations

wingless signal and Zeste-white 3 kinase trigger opposing changes in the intracellular distribution of Armadillo

1994 • 423 citations

Signal transduction by β-catenin

1995 • 398 citations

Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a protein kinase C.

1996 • 396 citations

Molecular organization of the uvomorulin-catenin complex.

1992 • 378 citations

Cadherins and catenins in development

1996 • 344 citations

Wnt-1 Regulates Free Pools of Catenins and Stabilizes APC-Catenin Complexes

1996 • 337 citations

Phosphorylation of the Drosophila Adherens Junction Protein Armadillo: Roles for Wingless Signal and Zeste-white 3 Kinase

1994 • 251 citations

The Tyrosine Kinase Substrate p120^cas Binds Directly to E-Cadherin but Not to the Adenomatous Polyposis Coli Protein or α-Catenin

1995 • 214 citations

Single Amino Acid Substitutions in Proteins of the armadillo Gene Family Abolish Their Binding to α-Catenin

1996 • 174 citations

Distinct cadherin—catenin complexes in Ca²⁺ dependent cell—cell adhesion

1994 • 120 citations

Regulating Cell Proliferation—As Easy as APC

1996 • 86 citations

Not just glue: cell-cell junctions as cellular signaling centers

1995 • 68 citations

Activity of Wnt-1 as a transmembrane protein.

1993 • 46 citations

Deleted Work

1955 • 0 citations