DNA-dependent protein kinase: DNA binding and activation in the absence of Ku

Meiosis-Specific DNA Double-Strand Breaks Are Catalyzed by Spo11, a Member of a Widely Conserved Protein Family

1997 • 1,751 citations

The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen

1993 • 1,219 citations

Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation

1995 • 862 citations

DNA-dependent protein kinase catalytic subunit: A relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

1995 • 742 citations

Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells

1997 • 667 citations

Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination

1994 • 637 citations

DNA-Dependent Kinase (p350) as a Candidate Gene for the Murine SCID Defect

1995 • 610 citations

Mechanism of interaction between Ku protein and DNA.

1986 • 485 citations

Human DNA-Activated Protein Kinase Phosphorylates Serines 15 and 37 in the Amino-Terminal Transactivation Domain of Human p53

1992 • 473 citations

The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination

1995 • 449 citations

Yeast DNA ligase IV mediates non-homologous DNA end joining

1997 • 412 citations

Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase II.

1992 • 367 citations

Restoration of X-ray Resistance and V(D)J Recombination in Mutant Cells by Ku cDNA

1994 • 351 citations

Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy studies

1997 • 315 citations

Binding of Ku protein to DNA. Measurement of affinity for ends and demonstration of binding to nicks.

1993 • 311 citations

The DNA-dependent Protein Kinase Is Inactivated by Autophosphorylation of the Catalytic Subunit

1996 • 287 citations

HeLa nuclear protein recognizing DNA termini and translocating on DNA forming a regular DNA-multimeric protein complex

1989 • 273 citations

Double Strand Break Repair

1997 • 268 citations

EBP-80, a transcription factor closely resembling the human autoantigen Ku, recognizes single- to double-strand transitions in DNA

1993 • 247 citations

Human DNA helicase II: a novel DNA unwinding enzyme identified as the Ku autoantigen.

1994 • 225 citations

Involvement of the Ku autoantigen in the cellular response to DNA double-strand breaks.

1994 • 215 citations

Analysis of the mechanism of interaction of simian Ku protein with DNA

1991 • 207 citations

A DNA end-binding factor involved in double-strand break repair and V(D)J recombination.

1994 • 164 citations

Purification and characterization of the double-stranded DNA-activated protein kinase, DNA-PK, from human placenta

1996 • 81 citations

Ku Selectively Transfers between DNA Molecules with Homologous Ends

1997 • 79 citations

DNA-Dependent ATPase from HeLa Cells Is Related to Human Ku Autoantigen

1994 • 79 citations

The end-joining reaction in V(D)J recombination

1997 • 76 citations

Human Ku Autoantigen Binds Cisplatin-damaged DNA but Fails to Stimulate Human DNA-activated Protein Kinase

1996 • 61 citations

A DNA End-Binding Factor Involved in Double-Strand Break Repair and V(D)J Recombination

1994 • 44 citations

Mechanism of DNA-Dependent Protein Kinase Inhibition by cis-Diamminedichloroplatinum(II)-Damaged DNA

1997 • 38 citations

A high-capacity column for affinity purification of sequence-specific DNA-binding proteins

1992 • 24 citations