In vivo estimates of extracellular dopamine and dopamine metabolite levels during intravenous cocaine or heroin self-administration

Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.

1988 • 4,617 citations

A psychomotor stimulant theory of addiction.

1987 • 2,704 citations

Cellular and Molecular Mechanisms of Drug Dependence

1988 • 2,094 citations

Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity

1991 • 2,025 citations

Brain Dopamine and Reward

1989 • 1,899 citations

Opioids excite dopamine neurons by hyperpolarization of local interneurons

1992 • 1,585 citations

Responses of monkey dopamine neurons during learning of behavioral reactions

1992 • 986 citations

Opposite effects of mu and kappa opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats.

1988 • 913 citations

New concepts in cocaine addiction: The dopamine depletion hypothesis

1985 • 608 citations

Effect of acute and daily cocaine treatment on extracellular dopamine in the nucleus accumbens

1990 • 538 citations

Postcocaine anhedonia. An animal model of cocaine withdrawal.

1991 • 505 citations

Morphine-induced activation of A10 dopamine neurons in the rat

1983 • 485 citations

Studies on the distinction between uptake inhibition and release of [3H]dopamine in rat brain tissue slices

1975 • 473 citations

Electrophysiological evidence for excitation of rat ventral tegmental area dopamine neurons by morphine

1984 • 424 citations

Dopamine in the nucleus accumbens during cocaine self-administration as studied by in vivo microdialysis

1989 • 386 citations

Differential involvement of ventral tegmental mu, delta and kappa opioid receptors in modulation of basal mesolimbic dopamine release: in vivo microdialysis studies.

1993 • 369 citations

Stimulus Properties of Drugs

1972 • 336 citations

Electrophysiological effects of cocaine in the mesoaccumbens dopamine system: studies in the ventral tegmental area

1988 • 313 citations

Amphetamine, cocaine, and fencamfamine: relationship between locomotor and stereotypy response profiles and caudate and accumbens dopamine dynamics

1991 • 289 citations

Extracellular Concentration and In Vivo Recovery of Dopamine in the Nucleus Accumbens Using Microdialysis

1992 • 278 citations

Opponent process theory of motivation: Neurobiological evidence from studies of opiate dependence

1989 • 264 citations

Toxicity Associated With Long-term Intravenous Heroin and Cocaine Self-administration in the Rat

1985 • 258 citations

Regulation of dopamine release by presynaptic nicotinic receptors in rat striatal slices: Effect of nicotine in a low concentration

1979 • 250 citations

Extracellular dopamine in rat striatum following uptake inhibition by cocaine, nomifensine and benztropine

1987 • 226 citations

Effect of dose on cocaine self-administration behavior and dopamine levels in the nucleus accumbens

1991 • 226 citations

Cocaine: An in vivo microdialysis evaluation of its acute action on dopamine transmission in rat striatum

1989 • 218 citations

Morphine-dopamine interaction: Ventral tegmental morphine increases nucleus accumbens dopamine release

1991 • 218 citations

Cocaine reinforcement and extracellular dopamine overflow in rat nucleus accumbens: an in vivo microdialysis study

1989 • 204 citations

Repeated cocaine administration induces behavioral sensitization and corresponding decreased extracellular dopamine responses in caudate and accumbens

1992 • 181 citations

Drug level of d- and l-amphetamine during intravenous self-administration

1974 • 172 citations

Apparent synaptic dopamine deficiency induced by withdrawal from chronic cocaine treatment

1991 • 126 citations

Pharmacological regulation of intravenous cocaine and heroin self-administration in rats: A variable dose paradigm

1989 • 115 citations

Enhanced extracellular dopamine level may be the fundamental neuropharmacological basis of cross-behavioral sensitization between methamphetamine and cocaine — an in vivo dialysis study in freely moving rats

1990 • 114 citations

Drug‐ and behavior‐associated changes in dopamine‐related electrochemical signals during intravenous heroin self‐administration in rats

1993 • 113 citations

In vivo electrochemical studies of monoamine release in the medial prefrontal cortex of the rat

1989 • 111 citations

Chronic cocaine alters limbic extracellular dopamine. Neurochemical basis for addiction

1992 • 99 citations

Conditioning of Opioid Reinforcement: Neuroanatomical and Neurochemical Substrates

1992 • 89 citations

The influence of cocaine self-administration on in vivo dopamine and acetylcholine neurotransmission in rat caudate-putamen

1990 • 65 citations

Acute depolarization block of A10 dopamine neurons: interactions of morphine with dopamine antagonists

1992 • 29 citations

Within‐subject sensitization of striatal dopamine release after a single injection of cocaine: An in vivo microdialysis study

1992 • 28 citations