Animal Lectins as Cell Adhesion Molecules

A C. elegans mutant that lives twice as long as wild type

1993 • 3,250 citations

RGD AND OTHER RECOGNITION SEQUENCES FOR INTEGRINS

1996 • 3,074 citations

Chemokines and leukocyte traffic

1998 • 2,755 citations

Lectins: Carbohydrate-Specific Proteins That Mediate Cellular Recognition

1998 • 1,707 citations

Identification of an inducible endothelial-leukocyte adhesion molecule.

1987 • 1,639 citations

Traffic Signals on Endothelium for Lymphocyte Recirculation and Leukocyte Emigration

1995 • 1,525 citations

A cell-surface molecule involved in organ-specific homing of lymphocytes

1983 • 1,515 citations

Galectins. Structure and function of a large family of animal lectins.

1994 • 1,487 citations

Adhesion molecules and inflammatory injury

1994 • 1,023 citations

The selecting: vascular adhesion molecules

1995 • 954 citations

Selectin ligands.

1994 • 943 citations

The biology of PECAM-1.

1997 • 669 citations

An endothelial ligand for L-Selectin is a novel mucin-like molecule

1992 • 660 citations

Leukocyte Trafficking Mediated by Selectin-Carbohydrate Interactions

1995 • 648 citations

Proteoglycans of the extracellular environment: clues from the gene and protein side offer novel perspectives in molecular diversity and function

1996 • 639 citations

Binding of L-Selectin to the Vascular Sialomucin CD34

1993 • 629 citations

Molecular interactions in cell adhesion complexes

1997 • 583 citations

SELECTIN-CARBOHYDRATE INTERACTIONS AND THE INITIATION OF THE INFLAMMATORY RESPONSE

1995 • 574 citations

The cutaneous lymphocyte antigen is a skin lymphocyte homing receptor for the vascular lectin endothelial cell-leukocyte adhesion molecule 1.

1991 • 557 citations

Recurrent Severe Infections Caused by a Novel Leukocyte Adhesion Deficiency

1992 • 555 citations

Lysosomal membrane glycoproteins. Structure, biosynthesis, and intracellular trafficking.

1991 • 552 citations

L-selectin-mediated lymphocyte rolling on MAdCAM-1

1993 • 540 citations

Distinct roles of L-selectin and integrins α4β7 and LFA-1 in lymphocyte homing to Peyer's patch-HEV in situ: The multistep model confirmed and refined

1995 • 520 citations

Integrin signalling and tyrosine phosphorylation: just the FAKs?

1998 • 502 citations

Role of PSGL-1 binding to selectins in leukocyte recruitment.

1997 • 491 citations

Galectins: A Family of Animal Lectins That Decipher Glycocodes

1996 • 488 citations

ENDOTHELIAL-LEUKOCYTE ADHESION MOLECULES IN HUMAN DISEASE

1994 • 461 citations

A sulfated peptide segment at the amino terminus of PSGL-1 is critical for P-selectin binding

1995 • 435 citations

PSGL-1 recognition of P-selectin is controlled by a tyrosine sulfation consensus at the PSGL-1 amino terminus

1995 • 383 citations

MAdCAM-1 has homology to immunoglobulin and mucin-like adhesion receptors and to IgA1

1993 • 383 citations

Glycosciences: Status and Perspectives

2002 • 382 citations

The E-selectin-ligand ESL-1 is a variant of a receptor for fibroblast growth factor

1995 • 358 citations

I-type Lectins

1995 • 318 citations

Endogenous galactoside-binding lectins: a new class of functional tumor cell surface molecules related to metastasis

1987 • 307 citations

Selectin ligands: will the real ones please stand up?

1997 • 307 citations

Tyrosine Sulfation of P-selectin Glycoprotein Ligand-1 Is Required for High Affinity Binding to P-selectin

1995 • 290 citations

Galectin-1 Is a Major Receptor for Ganglioside GM1, a Product of the Growth-controlling Activity of a Cell Surface Ganglioside Sialidase, on Human Neuroblastoma Cells in Culture

1998 • 284 citations

Lectin-carbohydrate complexes of plants and animals: an atomic view

1993 • 280 citations

Are changes in integrin affinity and conformation overemphasized?

1998 • 257 citations

Leukocyte adhesion deficiency type 1 (LAD-1)/variant. A novel immunodeficiency syndrome characterized by dysfunctional beta2 integrins.

1997 • 224 citations

Endogenous muscle lectin inhibits myoblast adhesion to laminin.

1991 • 224 citations

Leukocyte Adhesion

1997 • 219 citations

Calmodulin Regulates L-Selectin Adhesion Molecule Expression and Function through a Protease-Dependent Mechanism

1998 • 204 citations

Identification of a glycoprotein ligand for E-selectin on mouse myeloid cells.

1993 • 201 citations

Common Principles in Cell Adhesion

1996 • 199 citations

Evolution of Ca2+-dependent Animal Lectins

1993 • 197 citations

Functional evidence that cell surface galectin-3 mediates homotypic cell adhesion.

1995 • 197 citations

Affinity and Kinetic Analysis of L-selectin (CD62L) Binding to Glycosylation-dependent Cell-adhesion Molecule-1

1998 • 197 citations

Role of Galectin-1 in the Developing Mouse Olfactory System

1996 • 191 citations

GlyCAM-1, a physiologic ligand for L-selectin, activates beta 2 integrins on naive peripheral lymphocytes.

1996 • 184 citations

Glycoproteins and Their Relationship to Human Disease

1998 • 182 citations

Cancer-Associated Glycosphingolipid Antigens: Their Structure, Organization, and Function

1998 • 163 citations

Selective modulation of the interaction of α7β1 integrin with fibronectin and laminin by l-14 lectin during skeletal muscle differentiation

1994 • 156 citations

Adhesion Molecules-Their Role in Health and Disease

1996 • 153 citations

Increased content of an endogenous lactose-binding lectin in human colorectal carcinoma progressed to metastatic stages.

1991 • 152 citations

Novel functions for calreticulin: interaction with integrins and modulation of gene expression?

1994 • 151 citations

Carcinoembryonic antigen and other glycoconjugates act as ligands for galectin-3 in human colon carcinoma cells.

1995 • 145 citations

Lectins and Glycobiology

1993 • 145 citations

Rat olfactory neurons can utilize the endogenous lectin, L-14, in a novel adhesion mechanism

1994 • 145 citations

Selectins and mechanisms of signal transduction

1998 • 143 citations

Expression of galectins on microvessel endothelial cells and their involvement in tumour cell adhesion

1994 • 140 citations

Detection and functions of mammalian lectins — with emphasis on membrane lectins

1991 • 127 citations

Insights into Selectin Function from Knockout Mice

1997 • 123 citations

Rambam–Hasharon syndrome of psychomotor retardation, short stature, defective neutrophil motility, and bombay phenotype

1992 • 121 citations

Tissue fibronectin is an endogenous ligand for galectin-1

1995 • 116 citations

Carbohydrate-Protein Interactions in Vascular Biology

1995 • 115 citations

[Location of polyphosphatases, hydrolyzing polyphosphates to orthophosphates, in the subcellular structures of Neurospora crassa].

1972 • 113 citations

Leukocyte adhesion deficiency type II

1999 • 113 citations

The galectin family of mammalian carbohydrate-binding molecules

1997 • 112 citations

Endogenous Lectins in Tumors and the Immune System

1987 • 111 citations

Glycosylation-dependent cell adhesion molecule 1 (GlyCAM 1) mucin is expressed by lactating mammary gland epithelial cells and is present in milk.

1993 • 108 citations

The how and why of protein-carbohydrate interaction: a primer to the theoretical concept and a guide to application in drug design.

1998 • 101 citations

Concepts of Tumor Lectinology

1997 • 99 citations

Lectin localization in human nerve by biochemically defined lectin-binding glycoproteins, neoglycoprotein and lectin-specific antibody

1991 • 98 citations

Colon cancer mucin: a new ligand for the beta-galactoside-binding protein galectin-3.

1996 • 98 citations

Signaling Pathways for Transduction of the Initial Message of the Glycocode into Cellular Responses

1998 • 97 citations

Neoglycoproteins with the Synthetic Complex Biantennary Nonasaccharide or Its α2,3/α2,6-Sialylated Derivatives: Their Preparation, Assessment of Their Ligand Properties for Purified Lectins, for Tumor Cells in Vitro, and in Tissue Sections, and Their Biodistribution in Tumor-Bearing Mice

1997 • 94 citations

Localization of endogenous lectins in normal human breast, benign breast lesions and mammary carcinomas

1986 • 94 citations

Comparative cross-linking activities of lactose-specific plant and animal lectins and a natural lactose-binding immunoglobulin G fraction from human serum with asialofetuin

1996 • 91 citations

Plant Lectins – More than Just Tools for Glycoscientists: Occurrence, Structure, and Possible Functions of Plant Lectins

1998 • 88 citations

Concomitant increases in galectin-1 and its glycoconjugate ligands (carcinoembryonic antigen, lamp-1, and lamp-2) in cultured human colon carcinoma cells by sodium butyrate.

1994 • 80 citations

Lectin Ligands: New Insights into Their Conformations and Their Dynamic Behavior and the Discovery of Conformer Selection by Lectins

1998 • 77 citations

Soluble galactoside-binding vertebrate lectins: A protein family with common properties

1990 • 77 citations

Different Architecture of the Combining Site of the Two Chicken Galectins Revealed by Chemical Mapping Studies with Synthetic Ligand Derivatives

1996 • 72 citations

Glycobiology of the Olfactory System

1998 • 70 citations

Traffic Signals on Endothelium for Lymphocyte Recirculation and Leukocyte Emigration

1995 • 69 citations

Involvement of Laser Photo‐CIDNP(Chemically Induced Dynamic Nuclear Polarization)‐Reactive Amino Acid Side Chains in Ligand Binding by Galactoside‐Specific Lectins in Solution

1997 • 67 citations

Applications of Lectins and Neoglycoconjugates in Histology and Pathology

1998 • 66 citations

Lectin-parasite interactions

1996 • 65 citations

Identification of a soluble form of a ligand for the lymphocyte homing receptor.

1992 • 64 citations

Adhesive interactions in the immune system

1997 • 60 citations

L-Selectin Ligands That Are O-glycoprotease Resistant and Distinct from MECA-79 Antigen are Sufficient for Tethering and Rolling of Lymphocytes on Human High Endothelial Venules

1998 • 58 citations

Subsets of sialylated, sulfated mucins of diverse origins are recognized by L-selectin. Lack of evidence for unique oligosaccharide sequences mediating binding

1996 • 55 citations

Cell Adhesion Molecules: An Overview

1998 • 54 citations

Strategies for Glycoconjugate Analysis

1998 • 50 citations

Selectins, T-cell rolling and inflammation

1997 • 49 citations

Structural Basis of Lectin-Carbohydrate Recognition

1996 • 48 citations

NMR-Based, Molecular Dynamics- and Random Walk Molecular Mechanics-Supported Study of Conformational Aspects of a Carbohydrate Ligand (Galβ1-2Galβ1-R) for an Animal Galectin in the Free and in the Bound State

1996 • 43 citations

Protein-Carbohydrate Interactions during Fertilization

1998 • 43 citations

Integrins and Disease

1996 • 40 citations

Analysis of cell‐surface sugar receptor expression by neoglycoenzyme binding and adhesion to plastic‐immobilized neoglycoproteins for related weakly and strongly metastatic cell lines of murine tumor model systems

1990 • 40 citations

Structure and Functions of Lectins in the Central and Peripheral Nervous System

1998 • 40 citations

Glycoproteins Now and Then: A Personal Account

1998 • 38 citations

Differential Binding of Two Chicken β-Galactoside-Specific Lectins to Homologous Lymphocyte Subpopulations and Evidence for Inhibitor Activity of the Dimeric Lectin on Stimulated T Cells

1995 • 37 citations

Graph Theory and the EntropyConcept in Histochemistry

1997 • 36 citations

Protein-Zucker-Erkennung Grundlagen und Medizinische Anwendung am Beispiel der Tumorlektinologie

1995 • 34 citations

Detection of Inflammation- and Neoplasia-Associated Alterations in Human Large Intestine Using Plant/Invertebrate Lectins, Galectin-1 and Neoglycoproteins

1998 • 29 citations

Galectins Have Now Been Found in the Mushroom Coprinus cinereus

1997 • 26 citations

Quantitation and histochemical localization of galectin-1 and galectin-1-reactive glycoconjugates in fetal development of bovine organs.

1997 • 25 citations

Glycocoding as an Information Management System in Embryonic Development

1998 • 22 citations

Purification and Characterization of a Human Brain Galectin‐1 Ligand

1997 • 22 citations

Carbohydrate-binding proteins of tumor lines with different growth properties

1985 • 22 citations

Localization of Endogenous β-Galactoside-Specific Lectins by Neoglycoproteins, Lectin-Binding Tissue Glycoproteins and Antibodies and of Accessible Lectin-Specific Ligands by Mammalian Lectin in Human Breast Carcinomas

1991 • 21 citations

Endogenous tumor lectins: A new class of tumor markers and targets for therapy?

1985 • 20 citations

Carbohydrate–Carbohydrate Interaction

1996 • 18 citations

Glycoconjugate Expression and Cartilage Development of the Cranial Skeleton

1998 • 18 citations

Leukocyte adhesion deficiency-type 1 (LAD-1)/variant: A novel immunodeficiency syndrome characterized by dysfunctional β2 integrins

1997 • 16 citations

Histochemical study of expression of lectin-reactive carbohydrate epitopes and glycoligand-binding sites in normal human appendix vermiformis, colonic mucosa, acute appendicitis and colonic adenoma.

1996 • 16 citations

Leukocyte recruitment in inflammatory disease

1996 • 13 citations

Carbohydrate-dependent binding of human myeloid leukemia cell lines to neoglycoenzymes, matrix-immobilized neoglycoproteins, and bone marrow stromal cell layers

1994 • 12 citations

Adhesion of human lymphoid cell lines to immobilized carbohydrates and to bone‐marrow stromal cell layers by surface sugar receptors

1993 • 12 citations

Carbohydrate-Protein Interactions in Vascular Biology

1995 • 9 citations

Endogene Lektine in Tumoren und ihre mögliche Bedeutung für Diagnose und Therapie von Krebserkrankungen

1989 • 9 citations

Lectin Structure

1995 • 7 citations