Transient replication of human papillomavirus DNAs

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

A papillomavirus DNA from a cervical carcinoma and its prevalence in cancer biopsy samples from different geographic regions.

1983 • 2,011 citations

Structure and transcription of human papillomavirus sequences in cervical carcinoma cells

1985 • 1,481 citations

A new type of papillomavirus DNA, its presence in genital cancer biopsies and in cell lines derived from cervical cancer.

1984 • 1,308 citations

Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme

1989 • 1,244 citations

Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines

1987 • 760 citations

Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultured from human squamous cell carcinomas.

1981 • 743 citations

Heterogeneity of the human papillomavirus group

1989 • 677 citations

Transcription of human papillomavirus type 16 early genes in a cervical cancer and a cancer-derived cell line and identification of the E7 protein.

1986 • 665 citations

Analysis of the physical state of different human papillomavirus DNAs in intraepithelial and invasive cervical neoplasm

1991 • 585 citations

The Physical State of Human Papillomavirus Type 16 DNA in Benign and Malignant Genital Tumours

1985 • 480 citations

Transient replication of BPV-1 requires two viral polypeptides encoded by the E1 and E2 open reading frames.

1991 • 462 citations

Molecular cloning and characterization of human papilloma virus DNA derived from a laryngeal papilloma

1982 • 452 citations

Mutant keratin expression in transgenic mice causes marked abnormalities resembling a human genetic skin disease

1991 • 413 citations

Targeting the E1 Replication Protein to the Papillomavirus Origin of Replication by Complex Formation with the E2 Transactivator

1990 • 396 citations

Transcriptional regulation of the human papillomavirus-16 E6-E7 promoter by a keratinocyte-dependent enhancer, and by viral E2 trans-activator and repressor gene products: implications for cervical carcinogenesis.

1987 • 327 citations

Molecular cloning of viral DNA from human genital warts

1981 • 326 citations

Disruption of either the E1 or the E2 regulatory gene of human papillomavirus type 16 increases viral immortalization capacity.

1992 • 315 citations

The BPV1-E2 trans-acting protein can be either an activator or a repressor of the HPV18 regulatory region.

1987 • 294 citations

Activation of BPV-1 replication in vitro by the transcription factor E2

1991 • 284 citations

Amplification of human papillomavirus genomes in vitro is dependent on epithelial differentiation

1991 • 272 citations

Association between poor prognosis in early-stage invasive cervical carcinomas and non-detection of HPV DNA

1990 • 270 citations

Properties of a non‐tumorigenic human cervical keratinocyte cell line

1989 • 270 citations

The Role of Papillomaviruses in Human Anogenital Cancer

1987 • 267 citations

Mutational analysis of cis elements involved in E2 modulation of human papillomavirus type 16 P97 and type 18 P105 promoters

1990 • 265 citations

The upstream regulatory region of the human papilloma virus-16 contains an E2 protein-independent enhancer which is specific for cervical carcinoma cells and regulated by glucocorticoid hormones.

1987 • 257 citations

Identification of the origin of replication of bovine papillomavirus and characterization of the viral origin recognition factor E1.

1991 • 257 citations

The human papillomavirus type 18 (HPV18) E2 gene product is a repressor of the HPV18 regulatory region in human keratinocytes

1989 • 218 citations

Progesterone and glucocorticoid response elements occur in the long control regions of several human papillomaviruses involved in anogenital neoplasia

1989 • 203 citations

Chromosomal integration sites of human papillomavirus DNA in three cervical cancer cell lines mapped by in situ hybridization

1987 • 184 citations

Localization and analysis of bovine papillomavirus type 1 transforming functions

1984 • 173 citations

Functional analysis of E2-mediated repression of the HPV18 P105 promoter.

1991 • 132 citations

Papillomavirus DNA replication

1991 • 127 citations

The 68-kilodalton E1 protein of bovine papillomavirus is a DNA binding phosphoprotein which associates with the E2 transcriptional activator in vitro

1991 • 112 citations

Characterization of a transcriptional promoter of human papillomavirus 18 and modulation of its expression by simian virus 40 and adenovirus early antigens

1987 • 106 citations

Genetic analysis of the 3′ early region transformation and replication functions of bovine papillomavirus type 1

1986 • 106 citations

A bovine papillomavirus E1-related protein binds specifically to bovine papillomavirus DNA

1991 • 98 citations

Interplay of viral and cellular proteins along the long control region of human papillomavirus type 18

1988 • 98 citations

Bovine papillomavirus type 1 3' early region transformation and plasmid maintenance functions

1986 • 97 citations

Formation of the complex of bovine papillomavirus E1 and E2 proteins is modulated by E2 phosphorylation and depends upon sequences within the carboxyl terminus of E1.

1991 • 96 citations

Inducible and constitutive enhancer domains in the noncoding region of human papillomavirus type 18

1988 • 94 citations

Numerous nuclear proteins bind the long control region of human papillomavirus type 16: a subset of 6 of 23 DNase I-protected segments coincides with the location of the cell-type-specific enhancer

1989 • 90 citations

Identification of a 68-kilodalton nuclear ATP-binding phosphoprotein encoded by bovine papillomavirus type 1

1990 • 89 citations

Identification of a novel constitutive enhancer element and an associated binding protein: implications for human papillomavirus type 11 enhancer regulation

1989 • 83 citations

Transcriptional activation of the human papillomavirus-16 P97 promoter by an 88-nucleotide enhancer containing distinct cell-dependent and AP-1-responsive modules.

1990 • 83 citations

The viral transcriptional regulatory region upstream of the E6 and E7 genes is a major determinant of the differential immortalization activities of human papillomavirus types 16 and 18

1991 • 78 citations

A member of the activator protein 1 family found in keratinocytes but not in fibroblasts required for transcription from a human papillomavirus type 18 promoter

1990 • 75 citations

Production of human papillomavirus type 16 virions in a keratinocyte cell line

1990 • 73 citations

Differences in transformation activity between HPV-18 and HPV-16 map to the viral LCR-E6-E7 region

1991 • 66 citations

Bovine papillomavirus mutant temperature sensitive for transformation, replication and transactivation.

1988 • 55 citations

Multiple interactions between cellular factors and the non-coding region of human papillomavirus type 16

1990 • 41 citations

Replication of plasmid-derived human papillomavirus type 11 DNA in cultured keratinocytes

1992 • 40 citations

Proteins encoded by the bovine papillomavirus E1 open reading frame: expression in heterologous systems and in virally transformed cells

1990 • 37 citations

Delineation of human papillomavirus type 18 enhancer binding proteins: the intracellular distribution of a novel octamer binding protein p92 is cell cycle regulated

1991 • 35 citations

The bovine papillomavirus constitutive enhancer is essential for viral transformation, DNA replication, and the maintenance of latency

1992 • 23 citations