Type II DNA topoisomerases: Enzymes that can unknot a topologically knotted DNA molecule via a reversible double-strand break

On the mechanism of DNA replication in mammalian chromosomes

1968 • 950 citations

Interaction between DNA and an Escherichia coli protein ω

1971 • 749 citations

The interaction of closed circular DNA with intercalative dyes

1968 • 627 citations

Compact form of DNA induced by spermidine

1976 • 561 citations

A Sign Inversion Mechanism for Enzymatic Supercoiling of DNA

1979 • 325 citations

T4 DNA topoisomerase: a new ATP-dependent enzyme essential for initiation of T4 bacteriophage DNA replication

1979 • 262 citations

Statistical mechanics and topology of polymer chains

1975 • 218 citations

Proteins that Affect DNA Conformation

1978 • 215 citations

DNA Synthesis in vitro

1970 • 199 citations

DNA-DNA gyrase complex: the wrapping of the DNA duplex outside the enzyme

1978 • 195 citations

Knotted single-stranded DNA rings: A novel topological isomer of circular single-stranded DNA formed by treatment with Escherichia coli ω protein

1976 • 173 citations

Promoter-specific inhibition of transcription by antibiotics which act on DNA gyrase

1978 • 130 citations

Dependence of mammalian DNA replication on DNA supercoiling II. Effects of novobiocin on DNA synthesis in Chinese hamster ovary cells

1979 • 114 citations

Properties of the DNA-delay mutants of bacteriophage T4

1971 • 93 citations

Stepwise Relaxation of Supercoiled SV40 DNA

1974 • 89 citations

Structure and Activities of Escherichia coli DNA Gyrase

1979 • 78 citations

ι Protein from Drosophila melanogaster

1974 • 72 citations

DNA elongation rates and growing point distributions of wild-type phage T4 and a DNA-delay amber mutant

1976 • 69 citations

Gyrase-dependent initiation of bacteriophage T4 DNA replication: Interactions of Escherichia coli gyrase with novobiocin, coumermycin and phage DNA-delay gene products

1979 • 59 citations

H1 Histone and the Condensation of Chromatin and DNA

1978 • 50 citations