Late preconditioning against myocardial stunning. An endogenous protective mechanism that confers resistance to postischemic dysfunction 24 h after brief ischemia in conscious pigs.

Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene

1985 • 1,836 citations

Protection against infarction afforded by preconditioning is mediated by A1 adenosine receptors in rabbit heart.

1991 • 1,346 citations

Cardiac stress protein elevation 24 hours after brief ischemia or heat stress is associated with resistance to myocardial infarction.

1993 • 1,005 citations

Mechanism of myocardial "stunning".

1990 • 995 citations

Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70.

1985 • 860 citations

Delayed effects of sublethal ischemia on the acquisition of tolerance to ischemia.

1993 • 629 citations

The collateral circulation of the heart

1988 • 607 citations

Ischemic preconditioning reduces infarct size in swine myocardium.

1990 • 560 citations

Myocardial 'stunning' in man.

1992 • 531 citations

Heat-shock response is associated with enhanced postischemic ventricular recovery.

1988 • 489 citations

Insights into the pathogenesis of acute ischemic syndromes.

1988 • 483 citations

The oxygen free radical system: from equations through membrane-protein interactions to cardiovascular injury and protection

1992 • 400 citations

Preconditioning of ischemic myocardium: reperfusion-induced arrhythmias

1987 • 339 citations

Preconditioning causes improved wall motion as well as smaller infarcts after transient coronary occlusion in rabbits.

1991 • 329 citations

Heat shock protein induction in rat hearts. A role for improved myocardial salvage after ischemia and reperfusion?

1992 • 323 citations

Heat-shock response and limitation of tissue necrosis during occlusion/reperfusion in rabbit hearts.

1993 • 278 citations

Rapid expression of heat shock protein in the rabbit after brief cardiac ischemia.

1991 • 265 citations

A role for heat shock proteins in inflammation?

1988 • 262 citations

1,3-Dialkyl-8-(p-sulfophenyl)xanthines: potent water-soluble antagonists for A1- and A2-adenosine receptors

1985 • 223 citations

Time course and determinants of recovery of function after reversible ischemia in conscious dogs

1988 • 218 citations

Preconditioning does not attenuate myocardial stunning.

1992 • 194 citations

The protective role of heat stress in the ischaemic and reperfused rabbit myocardium

1992 • 174 citations

Stress proteins and myocardial protection

1992 • 169 citations

Acquisition and decay of heat-shock-enhanced postischemic ventricular recovery

1990 • 166 citations

Inhibition of protein synthesis does not block myocardial protection afforded by preconditioning

1990 • 153 citations

Cellular Mechanisms in Ischemic Preconditioning: The Role of Adenosine and Protein Kinase C a

1994 • 134 citations

The activity of xanthine oxidase in heart of pigs, guinea pigs, rabbits, rats, and humans

1987 • 133 citations

Reperfusion ventricular tachyarrhythmias: Correlation with antecedent coronary artery occlusion tachyarrhythmias and duration of myocardial ischemia

1981 • 128 citations

Rapid expression of fibronectin in the rabbit heart after myocardial infarction with and without reperfusion.

1992 • 128 citations

Development of coronary collateral circulation in left circumflex Ameroid-occluded swine myocardium

1987 • 125 citations

Demonstration of free radical generation in the "stunned" myocardium in the conscious dog and identification of major differences between conscious and open-chest dogs.

1993 • 109 citations

Postischemic myocardial "stunning". Identification of major differences between the open-chest and the conscious dog and evaluation of the oxygen radical hypothesis in the conscious dog.

1991 • 109 citations

Effect of long-term exercise on regional myocardial function and coronary collateral development after gradual coronary artery occlusion in pigs.

1990 • 97 citations

Preconditioning improves energy metabolism during reperfusion but does not attenuate myocardial stunning in porcine hearts.

1993 • 97 citations

Direct evidence that the hydroxyl radical plays a pathogenetic role in myocardial "stunning" in the conscious dog and demonstration that stunning can be markedly attenuated without subsequent adverse effects.

1993 • 94 citations

The pig as a model for myocardial ischemia and exercise.

1986 • 92 citations

The Mammalian Heat Shock (or Stress) Response: A Cellular Defense Mechanism

1987 • 91 citations

A single myocardial stretch or decreased systolic fiber shortening stimulates the expression of heat shock protein 70 in the isolated, erythrocyte-perfused rabbit heart.

1991 • 86 citations

Preconditioning myocardium with ischemia

1991 • 67 citations

Absence of detectable xanthine oxidase in human myocardium

1989 • 61 citations

Correlation of regional myocardial blood flow and function with myocardial infarct size during acute myocardial ischemia in the conscious pig.

1981 • 61 citations

Duration of ischemia is vital for collateral development: repeated brief coronary artery occlusions in conscious dogs.

1989 • 58 citations

Heparin accelerates coronary collateral development in a porcine model of coronary artery occlusion.

1993 • 56 citations

Whole body heat stress fails to limit infarct size in the reperfused rabbit heart

1992 • 42 citations

Chronic reduction of myocardial ischemia does not attenuate coronary collateral development in miniswine.

1992 • 37 citations

Adenosine is an endogenous protectant against stunning during repetitive ischemic episodes in the heart

1992 • 36 citations

Repeated dipyridamole administration enhances collateral-dependent flow and regional function during exercise. A role for adenosine.

1993 • 31 citations

Interventricular coronary steal induced by stenosis of left anterior descending coronary artery in exercising pigs.

1991 • 10 citations

Nisoldipine and perfusion of post‐stenotic myocardium in conscious pigs with different degrees of concentric stenosis

1988 • 9 citations

Diazepam administered prior to coronary artery occlusion increases latency to ventricular fibrillation

1991 • 8 citations

Response of collateral-dependent myocardium to vasopressin release during prolonged intense exercise

1993 • 7 citations

Differential effects of left anterior descending coronary occlusion on left and right ventricular anterior wall thickening in the conscious pig

1992 • 3 citations

Effect of preconditioning on regional contractile function: Combined experience from three protocols

1992 • 2 citations

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