Facilitatory and inhibitory transmitters modulate calcium influx during action potentials in Aplysia sensory neurons

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Living with Water Stress: Evolution of Osmolyte Systems

1982 • 3,735 citations

THE STRUCTURE AND REGULATION OF PROTEIN PHOSPHATASES

1989 • 2,518 citations

INTRACELLULAR CALCIUM HOMEOSTASIS

1987 • 2,183 citations

Molecular Biology of Learning: Modulation of Transmitter Release

1982 • 1,534 citations

Short-Term Synaptic Plasticity

1989 • 1,464 citations

How is the level of free arachidonic acid controlled in mammalian cells?

1982 • 1,193 citations

Time and calcium dependence of activation and inactivation of calcium-induced release of calcium from the sarcoplasmic reticulum of a skinned canine cardiac Purkinje cell.

1985 • 904 citations

Calcium Action in Synaptic Transmitter Release

1987 • 742 citations

Ion channels activated by inositol 1,4,5-trisphosphate in plasma membrane of human T-lymphocytes

1987 • 676 citations

Serotonin and cyclic AMP close single K+ channels in Aplysia sensory neurones

1982 • 658 citations

Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells

1987 • 640 citations

Intraterminal injection of synapsin I or calcium/calmodulin-dependent protein kinase II alters neurotransmitter release at the squid giant synapse.

1985 • 636 citations

Calcium ions, active zones and synaptic transmitter release

1988 • 609 citations

Calcium regulation of the neuronal growth cone

1988 • 581 citations

Calcium transport and buffering in neurons

1988 • 519 citations

Receptor-mediated activation of phospholipase A2 via GTP-binding proteins: arachidonic acid and its metabolites as second messengers

1988 • 512 citations

Regulation of calcium influx by second messengers in rat mast cells

1988 • 506 citations

Spontaneous release of transmitter from growth cones of embryonic neurones

1983 • 436 citations

α-Adrenergic inhibition of sympathetic neurotransmitter release mediated by modulation of N-type calcium-channel gating

1989 • 417 citations

Neurotransmitters decrease the calcium component of sensory neurone action potentials

1978 • 409 citations

Spatially Resolved Calcium Dynamics of Mammalian Purkinje Cells in Cerebellar Slice

1988 • 393 citations

Presynaptic modulation of voltage-dependent Ca ²⁺ current: Mechanism for behavioral sensitization in Aplysia californica

1978 • 385 citations

Intracellular injection of t he catalytic subunit of cyclic AMP-dependent protein kinase simulates facilitation of transmitter release underlying behavioral sensitization in Aplysia.

1980 • 380 citations

Mechanism of calcium current modulation underlying presynaptic facilitation and behavioral sensitization in Aplysia.

1980 • 363 citations

Cyclic AMP-dependent phosphorylation of a brain inositol trisphosphate receptor decreases its release of calcium.

1988 • 359 citations

Acetylcholine release from growth cones detected with patches of acetylcholine receptor-rich membranes

1983 • 356 citations

Serotonin modulates a specific potassium current in the sensory neurons that show presynaptic facilitation in Aplysia.

1982 • 350 citations

Subcellular Calcium Transients Visualized by Confocal Microscopy in a Voltage-Clamped Vertebrate Neuron

1990 • 341 citations

Regulation of neuronal function by calcium

1989 • 302 citations

Calcium diffusion modeling in a spherical neuron. Relevance of buffering properties

1990 • 299 citations

Digital imaging of free calcium changes and of spatial gradients in growing processes in single, mammalian central nervous system cells.

1986 • 298 citations

Spatial distribution of calcium channels and cytosolic calcium transients in growth cones and cell bodies of sympathetic neurons.

1988 • 294 citations

Imaging of cytosolic Ca2+ transients arising from Ca2+ stores and Ca2+ channels in sympathetic neurons

1988 • 281 citations

Neurite regeneration by Aplysia neurons in dissociated cell culture: modulation by Aplysia hemolymph and the presence of the initial axonal segment

1983 • 281 citations

Cyclic AMP-dependent protein kinase closes the serotonin-sensitive K+channels of Aplysia sensory neurones in cell-free membrane patches

1985 • 265 citations

Two endogenous neuropeptides modulate the gill and siphon withdrawal reflex in Aplysia by presynaptic facilitation involving cAMP-dependent closure of a serotonin-sensitive potassium channel.

1984 • 261 citations

Regulation of calcium homeostasis in sensory neurons by bradykinin

1988 • 257 citations

Release of calcium ions linked to the activation of potassium conductance in a caffeine‐treated sympathetic neurone.

1980 • 236 citations

Localization of voltage-sensitive calcium channels along developing neurites: Their possible role in regulating neurite elongation

1982 • 202 citations

Role for microsomal Ca storage in mammalian neurones?

1984 • 201 citations

The role of caffeine-sensitive calcium stores in the regulation of the intracellular free calcium concentration in rat sympathetic neurons in vitro.

1988 • 199 citations

Synaptic Plasticity and the Modulation of the Ca2+ Current

1980 • 190 citations

Distribution of two distinct Ca2+ -ATPase-like proteins and their relationships to the agonist-sensitive calcium store in adrenal chromaff in cells

1989 • 185 citations

Simulation of synaptic depression, posttetanic potentiation, and presynaptic facilitation of synaptic potentials from sensory neurons mediating gill-withdrawal reflex in Aplysia

1985 • 181 citations

Synaptic plasticity in vitro: cell culture of identified Aplysia neurons mediating short-term habituation and sensitization

1986 • 174 citations

Second messengers involved in the two processes of presynaptic facilitation that contribute to sensitization and dishabituation in Aplysia sensory neurons.

1990 • 173 citations

Calcium hotspots caused by L-channel clustering promote morphological changes in neuronal growth cones

1990 • 170 citations

Neuronal inhibition by the peptide FMRFamide involves opening of S K+ channels

1987 • 170 citations

Mechanism of Action of Caffeine on the Sarcoplasmic Reticulum of Skeletal Muscle

1975 • 156 citations

Contributions of Two Types of Calcium Channels to Synaptic Transmission and Plasticity

1990 • 132 citations

Pressure injection of calcium both excites and adapts Limulus ventral photoreceptors.

1986 • 127 citations

Facilitatory and inhibitory transmitters modulate spontaneous transmitter release at cultured Aplysia sensorimotor synapses.

1990 • 124 citations

A neuromodulator of synaptic transmission acts on the secretory apparatus as well as on ion channels

1989 • 117 citations

Action of organic antagonists on neuronal calcium currents

1985 • 102 citations

Sensitizing stimuli cause translocation of protein kinase C in Aplysia sensory neurons.

1990 • 102 citations

Modulation of potassium conductances by an endogenous neuropeptide in neurones of Aplysia californica.

1987 • 91 citations

The Jet Stream Microbeveler: An Inexpensive Way to Bevel Ultrafine Glass Micropipettes

1978 • 89 citations

Suppression of calcium current by an endogenous neuropeptide in neurones of Aplysia californica.

1987 • 81 citations

Differential synapse formation and neurite outgrowth at two branches of the metacerebral cell of Aplysia in dissociated cell culture

1985 • 80 citations

Inositol trisphosphate releases intracellularly stored calcium and modulates ion channels in molluscan neurons

1988 • 79 citations

Internal Potassium and Chloride Activities and the Effects of Acetylcholine on Identifiable Aplysia Neurones

1971 • 74 citations

Stimulation of phosphatidylinositol (PI) turnover may mediate the muscarinic suppression of the M-current in hippocampal pyramidal cells

1988 • 73 citations

Serotonin increases intracellular Ca2+ transients in voltage-clamped sensory neurons of Aplysia californica.

1984 • 68 citations

Fura-2 measurements of cultured rat Purkinje neurons show dendritic localization of Ca2+ influx

1989 • 66 citations

Changes in Intracellular Calcium During Neuron Activity

1989 • 66 citations

Activation of mitochondrial oxidative metabolism by calcium ions in Limulusventral photoreceptor

1988 • 65 citations

Presynaptic spike broadening reduces junctional potential amplitude

1989 • 60 citations

Role of two different guanine nucleotide-binding proteins in the antagonistic modulation of the S-type K+ channel by cAMP and arachidonic acid metabolites in Aplysia sensory neurons.

1988 • 58 citations

Protein kinase C activators inhibit the inositol trisphosphate‐mediated muscarinic current responses in rat lacrimal cells.

1987 • 53 citations

Non-uniform Ca2+ buffer distribution in a nerve cell body

1980 • 52 citations

Cytoplasmic free Ca in isolated snail neurons as revealed by fluorescent probe fura-2: Mechanisms of Ca recovery after Ca load and Ca release from intracellular stores

1989 • 49 citations

Receptor-Receptor Interactions

1987 • 46 citations

Intracellular free magnesium in neurones of Helix aspersa measured with ion‐selective micro‐electrodes.

1984 • 36 citations

The growth cones of Aplysia sensory neurons: Modulation by serotonin of action potential duration and single potassium channel currents

1986 • 35 citations

Spatial distribution of Ca currents in molluscan neuron cell bodies and regional differences in the strength of inactivation

1988 • 31 citations

Second messengers, phosphorylation and neurotransmitter release

1985 • 26 citations

Active Transport of Potassium and Chloride in an Identifiable Molluscan Neuron

1972 • 25 citations

Inositol lipids and calcium signalling

1990 • 24 citations

Inositol trisphosphate and activators of protein kinase C modulate membrane currents in tail motor neurons of Aplysia

1989 • 16 citations

Intracellular free Mg²⁺ in Balanus photoreceptor measured with Eriochrome Blue

1986 • 7 citations