Water structural changes in the bacteriorhodopsin photocycle: analysis by Fourier transform infrared spectroscopy

Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopy

1990 • 2,969 citations

Vibrational Spectroscopy and Conformation of Peptides, Polypeptides, and Proteins

1986 • 2,761 citations

[69] Isolation of the cell membrane of Halobacterium halobium and its fractionation into red and purple membrane

1974 • 1,690 citations

Bacteriorhodopsin and the purple membrane of halobacteria

1979 • 909 citations

Bacteriorhodopsin and Related Pigments of Halobacteria

1982 • 767 citations

Nobel lecture. The photosynthetic reaction centre from the purple bacterium Rhodopseudomonas viridis.

1989 • 634 citations

From Femtoseconds to Biology: Mechanism of Bacteriorhodopsin's Light-Driven Proton Pump

1991 • 532 citations

Raman Spectral Studies of the Effects of Temperature on Water Structure

1967 • 506 citations

Vibrational spectroscopy of bacteriorhodopsin mutants: light-driven proton transport involves protonation changes of aspartic acid residues 85, 96, and 212

1988 • 497 citations

Theory of the Increase in Rigidity of Rubber during Cure

1947 • 422 citations

Infrared Studies of Hydrogen Bonding of Water by the Matrix Isolation Technique

1957 • 370 citations

Reversible Photolysis of the Purple Complex in the Purple Membrane of Halobacterium halobium

1973 • 351 citations

Role of aspartate-96 in proton translocation by bacteriorhodopsin.

1989 • 348 citations

Water structure of a hydrophobic protein at atomic resolution: Pentagon rings of water molecules in crystals of crambin

1984 • 333 citations

Aspartic acid-96 is the internal proton donor in the reprotonation of the Schiff base of bacteriorhodopsin.

1989 • 318 citations

STRUCTURE AND DYNAMICS OF WATER SURROUNDING BIOMOLECULES

1987 • 296 citations

Light-driven protonation changes of internal aspartic acids of bacteriorhodopsin: an investigation of static and time-resolved infrared difference spectroscopy using [4-13C]aspartic acid labeled purple membrane

1985 • 294 citations

Water-Protein Interactions: Theory and Experiment

1991 • 239 citations

Distributions of water around amino acid residues in proteins

1988 • 216 citations

Comparison of two highly refined structures of bovine pancreatic trypsin inhibitor

1987 • 210 citations

Role of water in bacteriorhodopsin's chromophore: resonance Raman study

1984 • 208 citations

Replacement of aspartic acid-96 by asparagine in bacteriorhodopsin slows both the decay of the M intermediate and the associated proton movement.

1989 • 203 citations

Water molecules and exchangeable hydrogen ions at the active centre of bacteriorhodopsin localized by neutron diffraction

1990 • 170 citations

Nuclear magnetic resonance study of the Schiff base in bacteriorhodopsin: counterion effects on the nitrogen-15 shift anisotropy

1989 • 169 citations

X-ray studies of water in crystals of lysozyme

1983 • 168 citations

H₂O, HDO, and CH₃OH Infrared Spectra and Correlation with Solvent Basicity and Hydrogen Bonding

1971 • 153 citations

Factors affecting the C:N stretching in protonated retinal Schiff base: a model study for bacteriorhodopsin and visual pigments

1987 • 145 citations

Temperature dependence of the Raman OH-stretching overtone from liquid water

1984 • 139 citations

Distortions in the photocycle of bacteriorhodopsin at moderate dehydration

1991 • 136 citations

Fourier transform infrared study of the N intermediate of bacteriorhodopsin

1991 • 129 citations

Millisecond Fourier-transform infrared difference spectra of bacteriorhodopsin's M412 photoproduct.

1987 • 123 citations

Bacteriorhodopsin mutants containing single substitutions of serine or threonine residues are all active in proton translocation.

1991 • 113 citations

The Association of Water with Bases and Anions in an Inert Solvent¹

1965 • 112 citations

Time‐course and stoichiometry of light‐induced proton release and uptake during the photocycle of bacteriorhodopsin

1986 • 100 citations

Polarized Fourier transform infrared spectroscopy of bacteriorhodopsin. Transmembrane alpha helices are resistant to hydrogen/deuterium exchange

1990 • 99 citations

Infrared Measurements of the Association of Ethanol in Carbon Tetrachloride

1958 • 91 citations

Orientation of the protonated retinal Schiff base group in bacteriorhodopsin from absorption linear dichroism

1989 • 89 citations

Light-induced currents from oriented purple membrane

1990 • 89 citations

Hydration effects on cis—trans isomerization of bacteriorhodopsin

1977 • 81 citations

Photoisomerization in bacteriorhodopsin studied by FTIR, linear dichroism and photoselection experiments combined with quantum chemical theoretical analysis

1989 • 78 citations

Protonation and deprotonation of the M, N, and O intermediates during the bacteriorhodopsin photocycle

1990 • 62 citations

Protonation of a novel intermediate P is involved in the M → bR step of the bacteriorhodopsin photocycle

1986 • 47 citations

Light-induced currents from oriented purple membrane

1990 • 44 citations

The photoreaction of vacuum-dried rhodopsin at low temperature: Evidence for charge stabilization by water

1988 • 31 citations

The vibrational spectrum of water in liquid alkanes

1985 • 28 citations

[6] Low-frequency raman scattering from water and aqueous solutions: A direct measure of hydrogen bonding

1986 • 19 citations

O‐H stretching vibration in Fourier transform difference infrared spectra of bacteriorhodopsin

1991 • 8 citations