On the attribution and additivity of binding energies

Some Factors in the Interpretation of Protein Denaturation

1959 • 4,817 citations

The Hydrophobic Effect: Formation of Micelles and Biological Membranes

1991 • 3,370 citations

Linked Functions and Reciprocal Effects in Hemoglobin: A Second Look

1964 • 1,613 citations

Avidin

1975 • 1,425 citations

Enthalpy–entropy compensation phenomena in water solutions of proteins and small molecules: A ubiquitous properly of water

1970 • 1,173 citations

Entropic Contributions to Rate Accelerations in Enzymic and Intramolecular Reactions and the Chelate Effect

1971 • 980 citations

Binding Energy, Specificity, and Enzymic Catalysis: The Circe Effect

1975 • 844 citations

Mechanism of Actomyosin Atpase and the Problem of Muscle Contractio

1979 • 407 citations

The influence of polyvalency on the binding properties of antibodies

1972 • 396 citations

The characterization of myosin–product complexes and of product-release steps during the magnesium ion-dependent adenosine triphosphatase reaction

1974 • 364 citations

The mechanism of action of S-adenosylhomocysteinase.

1979 • 347 citations

Kinetic Analysis of ATPase Mechanisms

1976 • 285 citations

The transition of bovine trypsinogen to a trypsin-like state upon strong ligand binding

1979 • 184 citations

Substructure of the myosin molecule

1973 • 172 citations

The Utilization of Binding Energy in Coupled Vectorial Processes

1980 • 166 citations

Fundamentals of the chemistry and application of dyes

1972 • 107 citations

An editing mechanism for the methionyl-tRNA synthetase in the selection of amino acids in protein synthesis

1979 • 78 citations

The Binding Constant of ATP to Myosin S1 Fragment

1977 • 76 citations

Cysteinyl-tRNA synthetase from Escherichia coli does not need an editing mechanism to reject serine and alanine. High binding energy of small groups in specific molecular interactions

1979 • 74 citations

The binding of heavy meromyosin to F-actin.

1980 • 66 citations

An analysis of the substrate-induced rate effect in the phosphoglucomutase system

1976 • 59 citations

Active site topography of isoleucyl transfer ribonucleic acid synthetase of Escherichia coli B

1973 • 54 citations

Mechanism of action of enolase: effect of the .beta.-hydroxy group on the rate of dissociation of the .alpha.-carbon-hydrogen bond

1980 • 53 citations

Near Infrared Investigation of Interamide Hydrogen Bonding in Aqueous Solution

1964 • 52 citations

Reaction of peptide aldehydes with serine proteases. Implications for the entropy changes associated with enzymic catalysis

1979 • 49 citations

Binding of peptides to elastase. Implications for the mechanism of substrate hydrolysis

1974 • 47 citations

Heavy meromyosin binds actin with negative cooperativity

1978 • 41 citations

Kinetics of the reaction of cyclopropanone hydrate with yeast aldehyde dehydrogenase: a model for enzyme-substrate interaction

1980 • 26 citations

The Mechanism of Action of Methionyl-tRNA Synthetase from Escherichia coli. Inhibition by Adenosine and 8-Aminoadenosine of the Amino-Acid Activation Reaction

1975 • 25 citations

Evidence for a thiol reagent inhibiting choline acetyltransferase by reacting with the thiol group of coenzyme a forming a potent inhibitor

1976 • 24 citations

Determination of N,N-dimethylindolealkylamines in plasma, blood and urine extracts by radioimmunoassay and high pressure liquid chromatography.

1978 • 19 citations

Entropy contributions to rate accelerations of intramolecular reactions in water VS non-structured solvents

1973 • 12 citations

Segmental flexibility in the myosin molecule: Evidence from binding studies of myosin fragments with actin

1975 • 10 citations

Evaluation of group contributions to ligand binding

1979 • 9 citations