Cysteinyl-tRNA synthetase from Escherichia coli does not need an editing mechanism to reject serine and alanine. High binding energy of small groups in specific molecular interactions

Principles of protein–protein recognition

1975 • 1,028 citations

The frequency of errors in protein biosynthesis

1972 • 396 citations

Molecular Refractivity and Polarizability

1965 • 391 citations

Calculations of Conformations of Polypeptides

1968 • 387 citations

ON THE ROLE OF SOLUBLE RIBONUCLEIC ACID IN CODING FOR AMINO ACIDS

1962 • 320 citations

Active site titration and aminoacyl adenylate binding stoichiometry of aminoacyl-tRNA synthetases

1975 • 226 citations

Editing mechanisms in protein synthesis. Rejection of valine by the isoleucyl-tRNA synthetase

1977 • 226 citations

Minimization of polypeptide energy. I. Preliminary structures of bovine pancreatic ribonuclease S-peptide.

1967 • 200 citations

Enzyme hyperspecificity. Rejection of threonine by the valyl-tRNA synthetase by misacylation and hydrolytic editing

1976 • 192 citations

Site of aminoacylation of tRNAs from Escherichia coli with respect to the 2'- or 3'-hydroxyl group of the terminal adenosine.

1975 • 147 citations

Demonstration of two active sites on a monomeric aminoacyl-tRNA synthetase. Possible roles of negative cooperativity and half-of-the-sites reactivity in oligomeric enzymes

1975 • 117 citations

A neutron diffraction study of <scp>L</scp>-cysteine

1975 • 102 citations

Refinements of the crystal structures of DL-serine and anhydrous L-serine

1974 • 98 citations

Hydrolytic action of aminoacyl-tRNA synthetases from baker's yeast. "Chemical proofreading" of Thr-tRNA^Val by valyl-tRNA synthetase studied with modified tRNA^Val and amino acid analogs

1977 • 59 citations

Aminoacyl‐tRNA synthetases from baker's yeast: Reacting site of enzymatic aminoacylation is not uniform for all tRNAs

1975 • 51 citations

Amino Acid Pool of Escherichia coli during the Different Phases of Growth.

1970 • 49 citations

Isoleucyl‐tRNA synthetase from baker's yeast: The 3′‐hydroxyl group of the 3′‐terminal ribose is essential for preventing misacylation of tRNA^Ile‐C‐C‐A with misactivated valine

1975 • 43 citations

Initial position of aminoacylation of individual Escherichia coli, yeast, and calf liver transfer RNAs

1977 • 40 citations

Desulfurization of sulfur amino acids and proteins with Raney nickel

1971 • 24 citations

Binding energy and enzymic catalysis

1976 • 12 citations