A possible role for π‐stacking in the self‐assembly of amyloid fibrils
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Abstract
References (47)
Protein misfolding, evolution and disease
1999 • 1,948 citations
MODELS OF AMYLOID SEEDING IN ALZHEIMER'S DISEASE AND SCRAPIE: Mechanistic Truths and Physiological Consequences of the Time-Dependent Solubility of Amyloid Proteins
1997 • 1,621 citations
Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.
1994 • 1,313 citations
π-Stacking Interactions
1998 • 1,068 citations
Review: History of the Amyloid Fibril
2000 • 995 citations
Arrest of -Amyloid Fibril Formation by a Pentapeptide Ligand
1996 • 905 citations
β-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: Implications for Alzheimer's therapy
1998 • 839 citations
Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation.
1990 • 782 citations
Amyloid Fibril Formation by Aβ16-22, a Seven-Residue Fragment of the Alzheimer's β-Amyloid Peptide, and Structural Characterization by Solid State NMR
2000 • 681 citations
Amino acid substitution matrices from an information theoretic perspective
1991 • 637 citations
Support for the Prion Hypothesis for Inheritance of a Phenotypic Trait in Yeast
1996 • 620 citations
Islet amyloid: a long-recognized but underappreciated pathological feature of type 2 diabetes.
1999 • 483 citations
A stop-codon mutation in the BRI gene associated with familial British dementia
1999 • 462 citations
From the globular to the fibrous state: protein structure and structural conversion in amyloid formation
1998 • 452 citations
Aromatic π-Stacking in Solution as Revealed through the Aggregation of Phenylacetylene Macrocycles
1996 • 416 citations
Analysis of the Minimal Amyloid-forming Fragment of the Islet Amyloid Polypeptide
2001 • 411 citations
Identification of a penta- and hexapeptide of islet amyloid polypeptide (IAPP) with amyloidogenic and cytotoxic properties
2000 • 410 citations
?-? INTERACTIONS IN SELF-ASSEMBLY
1997 • 388 citations
An amyloid-forming peptide from the yeast prion Sup35 reveals a dehydrated β-sheet structure for amyloid
2001 • 376 citations
Arene—Arene Interactions: Electrostatic or Charge Transfer?
1993 • 367 citations
Conformational transitions of islet amyloid polypeptide (IAPP) in amyloid formation in Vitro
1999 • 346 citations
The core Alzheimer's peptide NAC forms amyloid fibrils which seed and are seeded by β-amyloid: is NAC a common trigger or target in neurodegenerative disease?
1995 • 277 citations
Identification of a novel human islet amyloid polypeptide β-sheet domain and factors influencing fibrillogenesis
2001 • 233 citations
The “Correctly Folded” State of Proteins: Is It a Metastable State?
2002 • 226 citations
Modified-Peptide Inhibitors of Amyloid β-Peptide Polymerization
1999 • 216 citations
Medin: An integral fragment of aortic smooth muscle cell-produced lactadherin forms the most common human amyloid
1999 • 206 citations
Interaction of the anthracycline 4'-iodo-4'-deoxydoxorubicin with amyloid fibrils: inhibition of amyloidogenesis.
1995 • 202 citations
Creating a Protein-Based Element of Inheritance
2000 • 176 citations
Tetracycline affects abnormal properties of synthetic PrP peptides and PrPSc in vitro11Edited by J. Karn
2000 • 161 citations
Aromatic van der Waals Clusters: Structure and Nonrigidity
1996 • 144 citations
Analysis of amylin cleavage products provides new insights into the amyloidogenic region of human amylin
1999 • 138 citations
Misfolding the Way to Disease
1996 • 132 citations
The N-terminal segment of protein AA determines its fibrillogenic property
1992 • 124 citations
Controlling Self‐Assembly
1997 • 123 citations
Preparation of synthetic human islet amyloid polypeptide (IAPP) in a stable conformation to enable study of conversion to amyloid‐like fibrils
2000 • 119 citations
Abnormal Properties of Prion Protein with Insertional Mutations in Different Cell Types
1998 • 88 citations
Senile aortic amyloid. Evidence for two distinct forms of localized deposits.
1992 • 77 citations
Yeast Prions and Their Prion-Forming Domain
2000 • 76 citations
Controlling Polymerization of β-Amyloid and Prion-derived Peptides with Synthetic Small Molecule Ligands
2000 • 69 citations
4′-Iodo-4′-Deoxydoxorubicin Disrupts the Fibrillar Structure of Transthyretin Amyloid
2000 • 60 citations
A short synthesis of the β-amyloid (Aβ) aggregation inhibitor 3-p-Toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran
1999 • 57 citations
Creation of amyloid fibrils from mutant Asn187 gelsolin peptides
1992 • 40 citations
Treatment of AL Amyloidosis with 4′-Iodo-4′-Deoxydoxorubicin: An Update
1999 • 40 citations
Calcitonin-like immunoreactivity of amyloid fibrils in medullary thyroid carcinomas
1988 • 24 citations
Prion protein amyloid and neurodegeneration
1995 • 20 citations
In vitro synthesis of "amyloid"fibrils from insulin, calcitonin and parathormone.
1976 • 18 citations
Homology of calcitonin with the amyloid-related proteins
1994 • 9 citations