Arrest of -Amyloid Fibril Formation by a Pentapeptide Ligand

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1984 • 5,166 citations

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1987 • 4,544 citations

Amyloid plaque core protein in Alzheimer disease and Down syndrome.

1985 • 4,276 citations

The molecular pathology of Alzheimer's disease

1991 • 2,603 citations

Hydrogen peroxide mediates amyloid β protein toxicity

1994 • 2,065 citations

The carboxy terminus of the .beta. amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease

1993 • 1,951 citations

Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

1993 • 1,422 citations

Cleavage of Amyloid β Peptide During Constitutive Processing of Its Precursor

1990 • 1,388 citations

Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

1994 • 1,313 citations

Spot-synthesis: an easy technique for the positionally addressable, parallel chemical synthesis on a membrane support

1992 • 1,052 citations

Apoptosis is induced by beta-amyloid in cultured central nervous system neurons.

1993 • 1,035 citations

Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs.

1992 • 982 citations

Cell Biology of the Amyloid beta-Protein Precursor and the Mechanism of Alzheimer's Disease

1994 • 749 citations

Alzheimer's Disease: A Central Role for Amyloid

1994 • 749 citations

Solution Structures of β Peptide and Its Constituent Fragments: Relation to Amyloid Deposition

1991 • 531 citations

Synthetic peptide homologous to beta protein from Alzheimer disease forms amyloid-like fibrils in vitro.

1987 • 475 citations

beta-Amyloid peptide and a 3-kDa fragment are derived by distinct cellular mechanisms.

1993 • 460 citations

Relative abundance of Alzheimer A beta amyloid peptide variants in Alzheimer disease and normal aging.

1994 • 455 citations

Substitutions of hydrophobic amino acids reduce the amyloidogenicity of Alzheimer's disease βA4 peptides

1992 • 406 citations

Prolines and Aamyloidogenicity in Fragments of the Alzheimer's Peptide .beta./A4

1995 • 306 citations

Reversible in vitro growth of Alzheimer disease beta-amyloid plaques by deposition of labeled amyloid peptide.

1992 • 195 citations

Binding of the dye congo red to the amyloid protein pig insulin reveals a novel homology amongst amyloid-forming peptide sequences

1992 • 174 citations

β‐Cyclodextrin interacts with the Alzheimer amyloid β‐A4 peptide

1994 • 114 citations

The Alzheimer A beta peptide develops protease resistance in association with its polymerization into fibrils.

1994 • 99 citations

Calmodulin Binds to Specific Sequences in the Cytoplasmic Domain of C-CAM and Down-regulates C-CAM Self-association

1996 • 72 citations

The Metabolic Pathway Generating p3, an Aβ-Peptide Fragment, Is Probably Non-Amyloidogenic

1994 • 30 citations