Relationships between p63 Binding, DNA Sequence, Transcription Activity, and Biological Function in Human Cells

In silico prediction of protein-protein interactions in human macrophages

2014 • 11,120 citations

Significance analysis of microarrays applied to the ionizing radiation response

2001 • 10,393 citations

Statistical significance for genomewide studies

2003 • 9,411 citations

Fitting a mixture model by expectation maximization to discover motifs in biopolymers.

1994 • 4,818 citations

Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells

2005 • 4,388 citations

The Transcriptional Landscape of the Mammalian Genome

2005 • 3,444 citations

Systematic determination of genetic network architecture

1999 • 2,535 citations

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

1999 • 2,179 citations

Transcriptional regulatory code of a eukaryotic genome

2004 • 2,174 citations

p63, a p53 Homolog at 3q27–29, Encodes Multiple Products with Transactivating, Death-Inducing, and Dominant-Negative Activities

1998 • 2,061 citations

p63 is a p53 homologue required for limb and epidermal morphogenesis

1999 • 1,963 citations

The p53 pathway: positive and negative feedback loops

2005 • 1,899 citations

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

2003 • 1,515 citations

Rank products: a simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments

2004 • 1,483 citations

Aligning Multiple Genomic Sequences With the Threaded Blockset Aligner

2004 • 1,473 citations

Chromosome-Wide Mapping of Estrogen Receptor Binding Reveals Long-Range Regulation Requiring the Forkhead Protein FoxA1

2005 • 1,328 citations

Control of Pancreas and Liver Gene Expression by HNF Transcription Factors

2004 • 1,293 citations

Identifying DNA and protein patterns with statistically significant alignments of multiple sequences.

1999 • 1,272 citations

Transcriptional Maps of 10 Human Chromosomes at 5-Nucleotide Resolution

2005 • 1,152 citations

A Global Map of p53 Transcription-Factor Binding Sites in the Human Genome

2006 • 1,137 citations

FatiGO: a web tool for finding significant associations of Gene Ontology terms with groups of genes

2004 • 1,098 citations

Unbiased Mapping of Transcription Factor Binding Sites along Human Chromosomes 21 and 22 Points to Widespread Regulation of Noncoding RNAs

2004 • 1,079 citations

Computational identification of Cis -regulatory elements associated with groups of functionally related genes in Saccharomyces cerevisiae 1 1Edited by F. E. Cohen

2000 • 1,031 citations

Global Identification of Human Transcribed Sequences with Genome Tiling Arrays

2004 • 1,020 citations

p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours

2000 • 979 citations

Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues

2005 • 977 citations

A high-resolution map of active promoters in the human genome

2005 • 922 citations

Large-Scale Transcriptional Activity in Chromosomes 21 and 22

2002 • 839 citations

Combining probability from independent tests: the weighted Z‐method is superior to Fisher's approach

2005 • 718 citations

Defining the CREB Regulon

2004 • 708 citations

Tumor predisposition in mice mutant for p63 and p73: Evidence for broader tumor suppressor functions for the p53 family

2005 • 490 citations

On the shoulders of giants: p63, p73 and the rise of p53

2002 • 485 citations

Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis

2002 • 449 citations

Intrinsic Histone-DNA Interactions and Low Nucleosome Density Are Important for Preferential Accessibility of Promoter Regions in Yeast

2005 • 333 citations

Diverse mechanisms regulate stem cell self-renewal

2004 • 330 citations

The ΔNp63α Phosphoprotein Binds the p21 and 14-3-3σ Promoters In Vivo and Has Transcriptional Repressor Activity That Is Reduced by Hay-Wells Syndrome-Derived Mutations

2003 • 326 citations

Distribution of NF-κB-binding sites across human chromosome 22

2003 • 302 citations

Perp Is a p63-Regulated Gene Essential for Epithelial Integrity

2005 • 298 citations

The common and distinct target genes of the p53 family transcription factors

2004 • 293 citations

Differential expression of p63 isoforms in normal tissues and neoplastic cells

2002 • 275 citations

Stem Cell Depletion Through Epidermal Deletion of Rac1

2005 • 242 citations

Down-regulation of p63 is required for epidermal UV-B-induced apoptosis.

2000 • 212 citations

CREB Binds to Multiple Loci on Human Chromosome 22

2004 • 172 citations

Genomic analysis of LexA binding reveals the permissive nature of the Escherichia coli genome and identifies unconventional target sites

2005 • 158 citations

Notch signaling in the integrated control of keratinocyte growth/differentiation and tumor suppression

2004 • 131 citations

Mutations in the p53 homolog p63: allele-specific developmental syndromes in humans

2002 • 117 citations

Discovering functional transcription-factor combinations in the human cell cycle

2005 • 89 citations

TRANSFAC, TRANSPATH and CYTOMER as starting points for an ontology of regulatory networks.

2004 • 55 citations

p63-Specific Activation of the BPAG-1e Promoter

2005 • 38 citations