Expression of platelet-derived growth factor and activated receptor in clinical specimens of epithelial ovarian cancer and ovarian carcinoma cell lines

Cancer Statistics, 2003

2003 • 3,302 citations

Cyclophosphamide and Cisplatin Compared with Paclitaxel and Cisplatin in Patients with Stage III and Stage IV Ovarian Cancer

1996 • 2,766 citations

Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor

1999 • 2,386 citations

Pericyte Loss and Microaneurysm Formation in PDGF-B-Deficient Mice

1997 • 2,136 citations

Cancer of the Ovary

2004 • 2,075 citations

NF-κB is a target of AKT in anti-apoptotic PDGF signalling

1999 • 1,830 citations

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB

1997 • 1,162 citations

The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

1997 • 1,075 citations

New Human Tumor Cell Lines

1975 • 974 citations

Human Tumor Cells in Vitro

1975 • 753 citations

c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines.

1994 • 747 citations

PDGF receptors as cancer drug targets

2003 • 462 citations

PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF beta-receptors.

1994 • 428 citations

Expression of Angiogenesis-Related Genes and Progression of Human Ovarian Carcinomas in Nude Mice

1998 • 377 citations

Comparative properties of five human ovarian adenocarcinoma cell lines.

1985 • 323 citations

Cancer of the Ovary

1993 • 288 citations

Platelet-Derived Growth Factor is AngiogenicIn Vivo

1992 • 276 citations

Enhanced c-erbB-2/neu expression in human ovarian cancer cells correlates with more severe malignancy that can be suppressed by E1A.

1993 • 261 citations

Acidic pH-induced elevation in interleukin 8 expression by human ovarian carcinoma cells.

2000 • 218 citations

Expression and prognostic significance of platelet-derived growth factor and its receptors in epithelial ovarian neoplasms.

1993 • 218 citations

Carboplatin and paclitaxel in ovarian carcinoma: a phase I study of the Gynecologic Oncology Group.

1996 • 213 citations

Platelet-derived growth factor receptor-beta is induced during tumor development and upregulated during tumor progression in endothelial cells in human gliomas.

1992 • 202 citations

B-type receptor for platelet-derived growth factor mediates a chemotactic response by means of ligand-induced activation of the receptor protein-tyrosine kinase.

1990 • 169 citations

Angiogenesis during human extraembryonic development involves the spatiotemporal control of PDGF ligand and receptor gene expression

1991 • 164 citations

Human microvascular endothelial cells express receptors for platelet-derived growth factor.

1991 • 154 citations

Modulation of platelet-derived growth factor receptor expression in microvascular endothelial cells during in vitro angiogenesis.

1994 • 152 citations

Platelet-derived growth factor receptors: A therapeutic target in solid tumors

2001 • 145 citations

Microvascular pericytes express platelet-derived growth factor-beta receptors in human healing wounds and colorectal adenocarcinoma.

1993 • 144 citations

Hypoxia-induced elevation in interleukin-8 expression by human ovarian carcinoma cells.

1999 • 127 citations

DNA Methylation in Ovarian Cancer

2001 • 118 citations

Chimaeric analysis reveals role of Pdgf receptors in all muscle lineages

1998 • 117 citations

The cell survival signal Akt is differentially activated by PDGF-BB, EGF, and FGF-2 in osteoblastic cells

2001 • 106 citations

The Effects of Platelet-Derived Growth Factor and Receptor on Normal and Neoplastic Human Ovarian Surface Epithelium

1998 • 95 citations

Trends in United States ovarian cancer mortality, 1979–1995

1999 • 65 citations

Blockade of Platelet-Derived Growth Factor Receptor-β Pathway Induces Apoptosis of Vascular Endothelial Cells and Disrupts Glomerular Capillary Formation in Neonatal Mice

2002 • 52 citations

Human ovarian tumors of epithelial origin express PDGF in vitro and in vivo

1994 • 39 citations

Deleted Work

1955 • 0 citations