Human Type II Fcγ Receptors Inhibit B Cell Activation by Interacting with the p21 -dependent Pathway

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav.

1994 • 886 citations

Recruitment and Activation of PTP1C in Negative Regulation of Antigen Receptor Signaling by FcγRIIB1

1995 • 535 citations

Structure and ligand recognition of the phosphotyrosine binding domain of Shc

1995 • 361 citations

COMPETITION OF 19S AND 7S ANTIGEN RECEPTORS IN THE REGULATION OF THE PRIMARY IMMUNE RESPONSE

1968 • 328 citations

Activators of protein kinase C down-regulate and phosphorylate the T3/T-cell antigen receptor complex of human T lymphocytes.

1985 • 267 citations

Identification of the tyrosine phosphatase PTP1C as a B cell antigen receptor-associated protein involved in the regulation of B cell signaling.

1995 • 260 citations

B cell antigen receptor cross-linking induces phosphorylation of the p21ras oncoprotein activators SHC and mSOS1 as well as assembly of complexes containing SHC, GRB-2, mSOS1, and a 145-kDa tyrosine-phosphorylated protein.

1994 • 169 citations

Cross-linking of IgG receptors inhibits membrane immunoglobulin-stimulated calcium influx in B lymphocytes.

1993 • 117 citations

Interaction of Shc with Adaptor Protein Adaptins

1996 • 114 citations

The role of p21ras in receptor tyrosine kinase signalling

1994 • 114 citations

Regulation of the immune response. V. An analysis of the function of the Fc portion of antibody in suppression of an immune response with respect to interaction with components of the lymphoid system.

1971 • 100 citations

Tyrosine Phosphorylation of Shc Is Mediated through Lyn and Syk in B Cell Receptor Signaling

1995 • 93 citations

B cell antigen receptor stimulation induces formation of a Shc-Grb2 complex containing multiple tyrosine-phosphorylated proteins.

1994 • 89 citations

Cross-linking of surface IgM stimulates the Ras/Raf-1/MEK/MAPK cascade in human B lymphocytes.

1994 • 83 citations

Co-capping of ras proteins with surface immunoglobulins in B lymphocytes

1990 • 81 citations

Antigen-induced B lymphocyte activation involves the p21ras and ras.GAP signaling pathway.

1993 • 73 citations

Phospholipase C-gamma 1 binding to intracellular receptors for activated protein kinase C.

1994 • 72 citations

Cross-linking of Fc gamma receptor to surface immunoglobulin on B cells provides an inhibitory signal that closes the plasma membrane calcium channel

1994 • 72 citations

Correlations among tyrosine phosphorylation of Shc, p72syk, PLC-gamma 1, and [Ca2+]i flux in Fc gamma RIIA signaling.

1994 • 59 citations

In Vivo and In Vitro Specificity of Protein Tyrosine Kinases for Immunoglobulin G Receptor (FcγRII) Phosphorylation

1996 • 56 citations

Activation of the p21ras pathway couples antigen receptor stimulation to induction of the primary response gene egr-1 in B lymphocytes.

1995 • 54 citations

Tyrosine-containing sequence motifs of the human immunoglobulin G receptors FcRIIb1 and FcRIIb2 essential for endocytosis and regulation of calcium flux in B cells.

1994 • 53 citations

The membrane immunoglobulin receptor utilizes a Shc/Grb2/hSOS complex for activation of the mitogen-activated protein kinase cascade in a B-cell line

1995 • 31 citations

Protein-tyrosine kinase activity tightly associated with human type II Fc gamma receptors.

1994 • 26 citations

Activation and proliferation signals in mouse B cells. VII. Calcium ionophores are non-mitogenic polyclonal B-cell activators.

1985 • 24 citations

The alternative splicing of human FcγRII mRNA is regulated by activation of B cells with mIgM cross‐linking, interleukin‐4, or phorbolester

1995 • 19 citations

Interaction of signaling molecules with human FcγRIIb1 and the role of various FcγRIIb isoforms in B-cell regulation

1995 • 11 citations

Fc gamma RII cross-linking inhibits anti-Ig-induced erg-1 and erg-2 expression in BCL1.

1994 • 10 citations