IL-22 Increases the Innate Immunity of Tissues

Antimicrobial peptides of multicellular organisms

2002 • 7,993 citations

Interleukin-10 and the Interleukin-10 Receptor

2001 • 6,422 citations

Atopic Dermatitis

2000 • 4,717 citations

Endogenous Antimicrobial Peptides and Skin Infections in Atopic Dermatitis

2002 • 1,898 citations

β-Defensins: Linking Innate and Adaptive Immunity Through Dendritic and T Cell CCR6

1999 • 1,760 citations

Atopic dermatitis

2003 • 1,102 citations

Defensins of vertebrate animals

2002 • 659 citations

Cutting Edge: Immune Cells as Sources and Targets of the IL-10 Family Members?

2002 • 580 citations

Interleukin (IL)-22, a Novel Human Cytokine That Signals through the Interferon Receptor-related Proteins CRF2–4 and IL-22R

2000 • 531 citations

Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis

1999 • 521 citations

Cloning and Characterization of IL-10-Related T Cell-Derived Inducible Factor (IL-TIF), a Novel Cytokine Structurally Related to IL-10 and Inducible by IL-9

2000 • 497 citations

Dendritic cell loss from nonlymphoid tissues after systemic administration of lipopolysaccharide, tumor necrosis factor, and interleukin 1.

1995 • 472 citations

Interleukin-22 (IL-22) Activates the JAK/STAT, ERK, JNK, and p38 MAP Kinase Pathways in a Rat Hepatoma Cell Line

2002 • 458 citations

Production of interleukin-8 by human dermal fibroblasts and keratinocytes in response to interleukin-1 or tumour necrosis factor.

1989 • 422 citations

Identification of the Functional Interleukin-22 (IL-22) Receptor Complex

2001 • 390 citations

Production of β-Defensin Antimicrobial Peptides by the Oral Mucosa and Salivary Glands

1999 • 366 citations

Human interleukin-10-related T cell-derived inducible factor: Molecular cloning and functional characterization as an hepatocyte-stimulating factor

2000 • 352 citations

Human β-Defensin-2 Production in Keratinocytes is Regulated by Interleukin-1, Bacteria, and the State of Differentiation

2002 • 321 citations

Evaluation of the effects of peptide antibiotics human β‐defensins‐1/‐2 and LL‐37 on histamine release and prostaglandin D₂production from mast cells

2001 • 320 citations

Evaluation of the effects of peptide antibiotics human β-defensins-1/-2 and LL-37 on histamine release and prostaglandin D2 production from mast cells

2001 • 280 citations

Interleukins 19, 20, and 24 Signal through Two Distinct Receptor Complexes

2002 • 260 citations

Identification, Cloning, and Characterization of a Novel Soluble Receptor That Binds IL-22 and Neutralizes Its Activity

2001 • 254 citations

Expression of β‐defensin 1 and 2 mRNA by human monocytes, macrophages and dendritic cells

2002 • 251 citations

Discovery of new human β-defensins using a genomics-based approach

2001 • 249 citations

Cloning and Characterization of IL-22 Binding Protein, a Natural Antagonist of IL-10-Related T Cell-Derived Inducible Factor/IL-22

2001 • 248 citations

A soluble class II cytokine receptor, IL-22RA2, is a naturally occurring IL-22 antagonist

2001 • 210 citations

IL-TIF/IL-22: genomic organization and mapping of the human and mouse genes

2000 • 204 citations

The Class II cytokine receptor (CRF2) family: overview and patterns of receptor–ligand interactions

2004 • 188 citations

By IL-1 Signaling, Monocyte-Derived Cells Dramatically Enhance the Epidermal Antimicrobial Response to Lipopolysaccharide

2003 • 180 citations

Acinar Cells of the Pancreas Are a Target of Interleukin-22

2001 • 170 citations

Contrasting disease patterns in psoriasis and atopic dermatitis

1987 • 132 citations

Interleukin-1 receptor antagonist in normal and psoriatic epidermis.

1992 • 126 citations

Multiple Mechanisms of Reduced Major Histocompatibility Complex Class II Expression in Endotoxin Tolerance

2003 • 76 citations

A novel, soluble homologue of the human IL-10 receptor with preferential expression in placenta

2001 • 64 citations

IL-22, in contrast to IL-10, does not induce Ig production, due to absence of a functional IL-22 receptor on activated human B cells

2002 • 45 citations