Distribution and role of heterotrimeric G proteins in the secretory pathway of polarized epithelial cells

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Intracellular Aspects of the Process of Protein Synthesis

1975 • 3,560 citations

Diversity of G Proteins in Signal Transduction

1991 • 1,990 citations

Type-Specific Regulation of Adenylyl Cyclase by G Protein βγ Subunits

1991 • 1,076 citations

Pathways of Protein Secretion in Eukaryotes

1985 • 1,050 citations

Molecular dissection of the secretory pathway

1992 • 985 citations

G Proteins: A Family of Signal Transducers

1986 • 975 citations

Hormonal stimulation of adenylyl cyclase through Gi-protein βγ subunits

1992 • 623 citations

Progress in Unraveling Pathways of Golgi Traffic

1985 • 615 citations

Involvement of GTP-binding “G” proteins in transport through the Golgi stack

1987 • 495 citations

β-COP, a 110 kd protein associated with non-clathrin-coated vesicles and the golgi complex, shows homology to β-adaptin

1991 • 489 citations

Farnesylated γ-subunit of photoreceptor G protein indispensable for GTP-binding

1990 • 389 citations

Small GTP-binding proteins in vesicular transport

1990 • 381 citations

A coat subunit of Golgi-derived non-clathrin-coated vesicles with homology to the clathrin-coated vesicle coat protein β-adaptin

1991 • 376 citations

Binding of ARF and β-COP to Golgi Membranes: Possible Regulation by a Trimeric G Protein

1991 • 359 citations

Recruitment of coat proteins onto Golgi membranes in intact and permeabilized cells: Effects of brefeldin A and G protein activators

1992 • 358 citations

Calcium and GTP: essential components in vesicular trafficking between the endoplasmic reticulum and Golgi apparatus.

1989 • 351 citations

A heterotrimeric G protein, G alpha i-3, on Golgi membranes regulates the secretion of a heparan sulfate proteoglycan in LLC-PK1 epithelial cells.

1991 • 304 citations

G-protein alpha-subunit expression, myristoylation, and membrane association in COS cells.

1990 • 277 citations

Fluoride is not an activator of the smaller (20-25 kDa) GTP-binding proteins

1991 • 267 citations

Myristoylation of an inhibitory GTP-binding protein alpha subunit is essential for its membrane attachment.

1990 • 225 citations

Dependence on pH of polarized sorting of secreted proteins

1987 • 212 citations

Multiple GTP-binding proteins participate in clathrin-coated vesicle-mediated endocytosis.

1993 • 188 citations

Multiple trimeric G-proteins on the trans-Golgi network exert stimulatory and inhibitory effects on secretory vesicle formation.

1992 • 184 citations

Guanine nucleotides modulate the effects of brefeldin A in semipermeable cells: regulation of the association of a 110-kD peripheral membrane protein with the Golgi apparatus.

1991 • 183 citations

The ras superfamily of small GTP-binding proteins

1990 • 180 citations

Reconstitution of protein transport from the endoplasmic reticulum to the Golgi complex in yeast: the acceptor Golgi compartment is defective in the sec23 mutant.

1988 • 172 citations

Evidence of a Role for Heterotrimeric GTP-Binding Proteins in Endosome Fusion

1992 • 137 citations

Identification of a 200-kD, brefeldin-sensitive protein on Golgi membranes

1992 • 120 citations

Trimeric G‐proteins of the trans‐Golgi network are involved in the formation of constitutive secretory vesicles and immature secretory granules

1991 • 117 citations

Membrane localization of the pertussis toxin-sensitive G-protein subunits alpha i-2 and alpha i-3 and expression of a metallothionein-alpha i-2 fusion gene in LLC-PK1 cells.

1990 • 112 citations

Requirement for GTP hydrolysis in the formation of secretory vesicles

1990 • 108 citations

Action of brefeldin A blocked by activation of a pertussis-toxin-sensitive G protein

1992 • 104 citations

G Protein Subunit, αi-3, Activates a Pertussis Toxin-Sensitive Na+ Channel from the Epithelial Cell Line, A6

1989 • 96 citations

Trimeric G proteins and vesicle formation

1992 • 94 citations

19F and 31P NMR spectroscopy of G protein alpha subunits. Mechanism of activation by Al3+ and F-

1991 • 82 citations

The Kidney Morphology, Biochemistry, Physiology

1971 • 74 citations

Purified epithelial Na+ channel complex contains the pertussis toxin-sensitive G alpha i-3 protein.

1992 • 71 citations

Studies on Nucleotide and Receptor Regulation of G_iProteins: Effects of Pertussis Toxin

1989 • 65 citations

Identification of a G protein in rough endoplasmic reticulum of canine pancreas.

1988 • 62 citations

G proteins and signal transduction.

1990 • 58 citations

Distinctive populations of basement membrane and cell membrane heparan sulfate proteoglycans are produced by cultured cell lines.

1987 • 56 citations

Disruption of microtubules alters polarity of basement membrane proteoglycan secretion in epithelial cells

1991 • 55 citations

Heterogeneous localization of G protein alpha-subunits in rat kidney

1991 • 48 citations

Distribution of G-proteins in rat liver plasma-membrane domains and endocytic pathways

1989 • 48 citations

Regulation of the G-protein alpha i-2 subunit gene in LLC-PK1 renal cells and isolation of porcine genomic clones encoding the gene promoter

1991 • 33 citations

Localization and polar distribution of several G-protein subunits along nephron segments

1991 • 28 citations

Disruption of microtubules alters polarity of basement membrane proteoglycan secretion in epithelial cells

1991 • 26 citations

High level expression of transfected G protein α_i3 subunit is required for plasma membrane targeting and adenylyl cyclase inhibition in NIH 3T3 fibroblasts

1992 • 22 citations

Antibodies against synthetic peptides as probes of G protein structure and function.

1990 • 19 citations

Co‐operative binding of hsp60 may promote transfer hsp70 and correct folding of imported proteins in mitochondria

1991 • 19 citations

Demonstration of GTP-binding proteins and ADP-ribosylated proteins in rat liver Golgi fraction

1989 • 13 citations

Identification and localization of pertussis toxin-sensitive GTP-binding proteins in bovine kidney glomeruli.

1991 • 4 citations