Back to search

The first CH domain of affixin activates Cdc42 and Rac1 through αPIX, a Cdc42/Rac1‐specific guanine nucleotide exchanging factor

Data up to Jan 2025

Published2004
Citations52
References42

Total Citations Per Year

Abstract

References (42)

Rho GTPases and the Actin Cytoskeleton

1998 • 6,129 citations

Rho GTPases in cell biology

2002 • 4,662 citations

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1995 • 4,387 citations

Cell Migration: A Physically Integrated Molecular Process

1996 • 3,909 citations

Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

1999 • 1,558 citations

Regulation of cell adhesion and anchorage-dependent growth by a new β1-integrin-linked protein kinase

1996 • 1,106 citations

Exploring the sequence space for tetracycline-dependent transcriptional activators: Novel mutations yield expanded range and sensitivity

2000 • 911 citations

Paxillin and focal adhesion signalling

2000 • 765 citations

Bidirectional signaling between the cytoskeleton and integrins

1999 • 765 citations

PAK Kinases Are Directly Coupled to the PIX Family of Nucleotide Exchange Factors

1998 • 745 citations

Genes to cells edited by Jun-ichi Tomizawa, Blackwell Science Ltd. Institutional: £218.00 (Europe), £242.00 (Rest of World), US$382.00 (USA and Canada). Individual: £65.00 (Europe), £72.00 (Rest of World), US$114.00 (USA and Canada) ISSN 1356 9597

1997 • 673 citations

Focal Adhesion Kinase: a regulator of focal adhesion dynamics and cell movement

2000 • 661 citations

Activation of Rac and Cdc42 by Integrins Mediates Cell Spreading

1998 • 638 citations

NEW EMBO MEMBER'S REVIEW: The integrin-actin connection, an eternal love affair

2003 • 480 citations

Paxillin LD4 Motif Binds PAK and PIX through a Novel 95-kD Ankyrin Repeat, ARF–GAP Protein: A Role in Cytoskeletal Remodeling

1999 • 466 citations

Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK

2000 • 454 citations

Integrin-linked kinase (ILK) and its interactors

2001 • 441 citations

Activation of Rac1 by a Crk SH3-binding protein, DOCK180

1998 • 426 citations

Identification of a Mouse p21Cdc42/Rac Activated Kinase

1995 • 395 citations

PAK to the future

1999 • 391 citations

Integrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulation

2003 • 389 citations

Prediction of the Coding Sequences of Unidentified Human Genes. I. The Coding Sequences of 40 New Genes (KIAA0001-KIAA0040) Deduced by Analysis of Randomly Sampled cDNA Clones from Human Immature Myeloid Cell Line KG-1 (Supplement)

1994 • 362 citations

Structural and Functional Regulation of Tight Junctions by RhoA and Rac1 Small GTPases

1998 • 349 citations

C. elegans PAT-4/ILK Functions as an Adaptor Protein within Integrin Adhesion Complexes

2002 • 308 citations

Effects of Regulated Expression of Mutant RhoA and Rac1 Small GTPases on the Development of Epithelial (MDCK) Cell Polarity

1998 • 297 citations

Prediction of the Coding Sequences of Unidentified Human Genes. I. The Coding Sequences of 40 New Genes (KIAA0001-KIAA0040) Deduced by Analysis of Randomly Sampled cDNA Clones from Human Immature Myeloid Cell Line KG-1

1994 • 240 citations

A New Focal Adhesion Protein That Interacts with Integrin-Linked Kinase and Regulates Cell Adhesion and Spreading

2001 • 228 citations

A Novel Integrin-Linked Kinase–Binding Protein, Affixin, Is Involved in the Early Stage of Cell–Substrate Interaction

2001 • 207 citations

Actopaxin, a New Focal Adhesion Protein That Binds Paxillin Ld Motifs and Actin and Regulates Cell Adhesion

2000 • 196 citations

Control of Intramolecular Interactions between the Pleckstrin Homology and Dbl Homology Domains of Vav and Sos1 Regulates Rac Binding

2000 • 185 citations

The LD4 motif of paxillin regulates cell spreading and motility through an interaction with paxillin kinase linker (PKL)

2001 • 164 citations

Paxillin-dependent Paxillin Kinase Linker and p21-Activated Kinase Localization to Focal Adhesions Involves a Multistep Activation Pathway

2002 • 156 citations

Parvin, a 42 kDa focal adhesion protein, related to the α-actinin superfamily

2001 • 148 citations

Integration of Cell Attachment, Cytoskeletal Localization, and Signaling by Integrin-linked Kinase (ILK), CH-ILKBP, and the Tumor Suppressor PTEN

2003 • 136 citations

αPix Stimulates p21-activated Kinase Activity through Exchange Factor-dependent and -independent Mechanisms

1999 • 122 citations

Interaction of alphaPIX (ARHGEF6) with beta-parvin (PARVB) suggests an involvement of alphaPIX in integrin-mediated signaling

2003 • 115 citations

C. elegans PAT-6/Actopaxin Plays a Critical Role in the Assembly of Integrin Adhesion Complexes In Vivo

2003 • 98 citations

Cdc42, Rac1, and the Wiskott-Aldrich syndrome protein are involved in the cytoskeletal regulation of B lymphocytes

2001 • 94 citations

Roles for βpat-3 Integrins in Development and Function ofCaenorhabditis elegans Muscles and Gonads

2001 • 85 citations

Identification of the regulatory autophosphorylation site of autophosphorylation-dependent protein kinase (auto-kinase)

1998 • 58 citations

Construction of Epstein–Barr Virus-Based Expression Vector Containing Mini-OriP

1999 • 54 citations

Over‐expression of PAR‐3 suppresses contact‐mediated inhibition of cell migration in MDCK cells

2002 • 23 citations

Cited By (0)

Loading...