Identification of the regulatory autophosphorylation site of autophosphorylation-dependent protein kinase (auto-kinase)

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

1987 • 11,491 citations

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

1977 • 5,640 citations

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

Principles of CDK regulation

1995 • 3,267 citations

Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

1995 • 2,402 citations

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1994 • 1,520 citations

[11] Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates

1991 • 1,463 citations

CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme.

1994 • 1,239 citations

Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase).

1991 • 1,041 citations

Calcium-activated, phospholipid-dependent protein kinase from rat brain. Subcellular distribution, purification, and properties.

1982 • 1,008 citations

Crystal structure of cyclin-dependent kinase 2

1993 • 946 citations

Membrane and Morphological Changes in Apoptotic Cells Regulated by Caspase-Mediated Activation of PAK2

1997 • 742 citations

Modulation of the glycogen synthase kinase-3 family by tyrosine phosphorylation.

1993 • 616 citations

Atomic structure of the MAP kinase ERK2 at 2.3 Å resolution

1994 • 591 citations

Expression of Constitutively Active α-PAK Reveals Effects of the Kinase on Actin and Focal Complexes

1997 • 560 citations

Acid and base hydrolysis of phosphoproteins bound to Immobilon facilitates analysis of phosphoamino acids in gel-fractionated proteins

1989 • 469 citations

Regulation of Human Leukocyte p21-Activated Kinases Through G Protein—Coupled Receptors

1995 • 415 citations

Identification of a Mouse p21Cdc42/Rac Activated Kinase

1995 • 395 citations

A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20.

1995 • 365 citations

[8] Use of glutaraldehyde as a coupling agent for proteins and peptides

1980 • 313 citations

Rapid visualization of protein bands in preparative SDS-polyacrylamide gels

1979 • 310 citations

Emerging from the Pak: the p21-activated protein kinase family

1997 • 285 citations

Molecular Cloning of a New Member of the p21-Cdc42/Rac-activated Kinase (PAK) Family

1995 • 240 citations

Synergistic phosphorylation and activation of ATP-Mg-dependent phosphoprotein phosphatase by F A/GSK-3 and casein kinase II (PC0.7).

1984 • 212 citations

Autophosphorylation-activated protein kinase phosphorylates and inactivates protein phosphatase 2A.

1993 • 159 citations

Characterisation of a Reconstituted Mg‐ATP‐Dependent Protein Phosphatase

1983 • 154 citations

Sequence of two phosphorylated sites in the catalytic subunit of bovine cardiac muscle adenosine 3‘:5‘-monophosphate-dependent protein kinase.

1979 • 145 citations

Autoactivation of catalytic (C alpha) subunit of cyclic AMP-dependent protein kinase by phosphorylation of threonine 197.

1993 • 141 citations

Mechanism of interferon action: evidence for intermolecular autophosphorylation and autoactivation of the interferon-induced, RNA-dependent protein kinase PKR

1993 • 132 citations

Identification and Molecular Cloning of a p21cdc42/rac1-activated Serine/Threonine Kinase That Is Rapidly Activated by Thrombin in Platelets

1995 • 132 citations

Solid‐Phase Methods in Protein Sequence Analysis

1980 • 110 citations

Transfer of proteins to membranes facilitates both cyanogen bromide cleavage and two-dimensional proteolytic mapping.

1990 • 100 citations

Activation of an S6/H4 Kinase (PAK 65) from Human Placenta by Intramolecular and Intermolecular Autophosphorylation

1995 • 80 citations

Molecular Cloning and Sequencing of the Cytostatic G Protein-activated Protein Kinase PAK I

1996 • 77 citations

Single step purification of the catalytic subunit(s) of cyclic 3′,5′-adenosine monophosphate-dependent protein kinase(s) from rat muscle

1976 • 73 citations

Purification and characterization of an autophosphorylation-activated protein serine threonine kinase that phosphorylates and inactivates protein phosphatase 2A

1993 • 56 citations

Protein Kinase F_A/Glycogen Synthase Kinase‐3 Predominantly Phosphorylates the In Vivo Site Thr⁹⁷‐Pro in Brain Myelin Basic Protein: Evidence for Thr‐Pro and Ser‐Arg‐X‐X‐Ser as Consensus Sequence Motifs

1994 • 53 citations

Methods of Biochemical Analysis

1980 • 42 citations

Okadaic acid, a serine/threonine phosphatase inhibitor, induces tyrosine dephosphorylation/inactivation of protein kinase FA/GSK-3 alpha in A431 cells.

1994 • 38 citations

Autoactivation of Catalytic (Cα) Subunit of Cyclic AMP-Dependent Protein Kinase by Phosphorylation of Threonine 197

1993 • 29 citations

Tyrosin dephosphorylation and concurrent inactivation of protein kinase F_A/GSK‐3α by genistein in A431 cells

1994 • 29 citations

Immunological and biochemical study on tissue and subcellular distributions of protein kinase FA (an activating factor of ATP.Mg-dependent protein phosphatase): A simplified and efficient procedure for high quantity purification from brain

1993 • 28 citations

Functional studies of P-glycoprotein in inside-out plasma membrane vesicles derived from murine erythroleukemia cells overexpressing MDR 3.

1995 • 22 citations

Autophosphorylation-dependent protein kinase phosphorylates Ser25, Ser38, Ser65, Ser71, and Ser411 in vimentin and thereby inhibits cytoskeletal intermediate filament assembly

1994 • 21 citations

Characterization of an autophosphorylation-dependent multifunctional protein kinase from liver.

1987 • 19 citations

Identification and characterization of a phosphorylation-activated, cyclic AMP and Ca2+-independent protein kinase in the brain.

1987 • 16 citations

Activation of an S6 kinase from human placenta by autophosphorylation.

1993 • 12 citations

Phosphorylation/Activation of Phosphorylase b Kinase by cAMP/Ca2+-Independent, Autophosphorylation-Dependent Protein Kinase

1995 • 8 citations

Effect of Mg2+ concentrations on phosphorylation/activation of phosphorylase b kinase by cAMP/Ca2+-independent, autophosphorylation-dependent protein kinase

1995 • 5 citations