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Apicobasal polarization: epithelial form and function

Data up to Jan 2025

Published2003
Citations125
References38

Total Citations Per Year

Abstract

References (38)

Multifunctional strands in tight junctions

2001 • 2,392 citations

The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42

2000 • 913 citations

Cooperative Regulation of Cell Polarity and Growth by Drosophila Tumor Suppressors

2000 • 908 citations

Disruption of the Epithelial Apical-Junctional Complex by Helicobacter pylori CagA

2003 • 708 citations

Adaptation of core mechanisms to generate cell polarity

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Expression of crumbs confers apical character on plasma membrane domains of ectodermal epithelia of drosophila

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Localization of apical epithelial determinants by the basolateral PDZ protein Scribble

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Links between signal transduction, transcription and adhesion in epithelial bud development

2003 • 564 citations

The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl

2003 • 553 citations

Epithelial Cell Polarity and Cell Junctions inDrosophila

2001 • 516 citations

An Atypical PKC Directly Associates and Colocalizes at the Epithelial Tight Junction with ASIP, a Mammalian Homologue of Caenorhabditis elegans Polarity Protein PAR-3

1998 • 508 citations

Direct interaction of two polarity complexes implicated in epithelial tight junction assembly

2003 • 476 citations

Drosophila Atypical Protein Kinase C Associates with Bazooka and Controls Polarity of Epithelia and Neuroblasts

2000 • 467 citations

Integrated activity of PDZ protein complexes regulates epithelial polarity

2002 • 436 citations

Composition and Formation of Intercellular Junctions in Epithelial Cells

2002 • 415 citations

armadillo, bazooka, and stardust are critical for early stages in formation of the zonula adherens and maintenance of the polarized blastoderm epithelium in Drosophila.

1996 • 390 citations

A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl

2003 • 368 citations

The LIN-2/LIN-7/LIN-10 Complex Mediates Basolateral Membrane Localization of the C. elegans EGF Receptor LET-23 in Vulval Epithelial Cells

1998 • 366 citations

Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization

2002 • 359 citations

Claudin-based barrier in simple and stratified cellular sheets

2002 • 355 citations

Segregation of receptor and ligand regulates activation of epithelial growth factor receptor

2003 • 355 citations

Mammalian Lgl Forms a Protein Complex with PAR-6 and aPKC Independently of PAR-3 to Regulate Epithelial Cell Polarity

2003 • 346 citations

Drosophila Stardust is a partner of Crumbs in the control of epithelial cell polarity

2001 • 280 citations

Discs Lost, a Novel Multi-PDZ Domain Protein, Establishes and Maintains Epithelial Polarity

1999 • 273 citations

LET-23 Receptor Localization by the Cell Junction Protein LIN-7 during C. elegans Vulval Induction

1996 • 268 citations

Neuroglian, Gliotactin, and the Na+/K+ ATPase are essential for septate junction function inDrosophila

2003 • 239 citations

Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts

2001 • 233 citations

Crumbs, a Component of the Apical Membrane, Is Required for Zonula Adherens Formation in Primary Epithelia ofDrosophila

1996 • 229 citations

Polarized Insertion of New Membrane from a Cytoplasmic Reservoir during Cleavage of the Drosophila Embryo

2000 • 215 citations

Drosophila coracle, a Member of the Protein 4.1 Superfamily, Has Essential Structural Functions in the Septate Junctions and Developmental Functions in Embryonic and Adult Epithelial Cells

1998 • 189 citations

Crumbs interacts with moesin and βHeavy-spectrin in the apical membrane skeleton of Drosophila

2002 • 185 citations

Mammalian Homolog of Drosophila Tumor Suppressor Lethal (2) Giant Larvae Interacts with Basolateral Exocytic Machinery in Madin-Darby Canine Kidney Cells

2002 • 183 citations

How one becomes many: Blastoderm cellularization in Drosophila melanogaster

2002 • 166 citations

slam Encodes a Developmental Regulator of Polarized Membrane Growth during Cleavage of the Drosophila Embryo

2002 • 110 citations

Tumor suppressors: Linking cell polarity and growth control

2000 • 92 citations

Slow as Molasses is required for polarized membrane growth and germ cell migration inDrosophila

2002 • 61 citations

Localization and modulation of ErbB receptor tyrosine kinases

2001 • 54 citations

Membrane receptor location defines receptor interaction with signaling proteins in a polarized epithelium

1999 • 21 citations

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