MMP-10 Is Overexpressed, Proteolytically Active, and a Potential Target for Therapeutic Intervention in Human Lung Carcinomas

New functions for the matrix metalloproteinases in cancer progression

2002 • 5,937 citations

Strategies for MMP inhibition in cancer: innovations for the post-trial era

2002 • 1,309 citations

Extracellular matrix remodelling: the role of matrix metalloproteinases

2003 • 1,061 citations

Human and mouse proteases: a comparative genomic approach

2003 • 903 citations

Matrix metalloproteinases in tumor invasion and metastasis

2000 • 820 citations

Matrix metalloproteinases in cancer: Prognostic markers and therapeutic targets

2002 • 635 citations

Metalloproteinases: role in breast carcinogenesis, invasion and metastasis

2000 • 598 citations

Activation of Matrix Metalloproteinase-9 (MMP-9) via a Converging Plasmin/Stromelysin-1 Cascade Enhances Tumor Cell Invasion

1999 • 583 citations

Critical appraisal of the use of matrix metalloproteinase inhibitors in cancer treatment

2000 • 545 citations

Molecular Determinants of Metalloproteinase Substrate Specificity: Matrix Metalloproteinase Substrate Binding Domains, Modules, and Exosites

2002 • 493 citations

Mechanisms for pro matrix metalloproteinase activation

1999 • 436 citations

Matrix metalloproteinases in cancer invasion, metastasis and angiogenesis

2001 • 250 citations

Distinct populations of basal keratinocytes express stromelysin-1 and stromelysin-2 in chronic wounds.

1994 • 238 citations

Expression of collagenase‐related metalloproteinase genes in human lung or head and neck tumours

1991 • 210 citations

Expression of matrix metalloproteinases and their inhibitors correlates with invasion and metastasis in squamous cell carcinoma of the head and neck.

2001 • 209 citations

Patterns of matrix metalloproteinase and TIMP-1 expression in chronic and normally healing human cutaneous wounds.

1996 • 191 citations

Differential expression of matrilysin‐1 (MMP‐7), 92 kD gelatinase (MMP‐9), and metalloelastase (MMP‐12) in oral verrucous and squamous cell cancer

2003 • 163 citations

Activation of the precursor of human stromelysin 2 and its interactions with other matrix metalloproteinases

1998 • 126 citations

Biological and clinical relevance of Laminin-5 in cancer.

2000 • 119 citations

Overexpression of Matrix Metalloproteinase-10 and Matrix Metalloproteinase-3 in Human Diabetic Corneas

2001 • 111 citations

Stromelysin-2 is Upregulated During Normal Wound Repair and is Induced by Cytokines

2000 • 109 citations

Stromelysin-1 (MMP-3) and Stromelysin-2 (MMP-10) Expression in Developing Human Bone: Potential Roles in Skeletal Development

1998 • 109 citations

Patterns of matrix metalloproteinase and TIMP-1 expression in chronic and normally healing human cutaneous wounds

1996 • 109 citations

Increased expression of laminin-5 and its prognostic significance in lung adenocarcinomas of small size

2001 • 93 citations

Differential patterns of stromelysin-2 (MMP-10) and MT1-MMP (MMP-14) expression in epithelial skin cancers

2001 • 89 citations

[27] Human stromelysins 1 and 2

1995 • 84 citations

MMP expression profiling in recurred stage IB lung cancer

2003 • 60 citations

Expression of the laminin ?2 chain in different histological types of lung carcinoma. A study by immunohistochemistry andin situ hybridization

1999 • 57 citations

Urokinase plasminogen activator: a prognostic marker in breast cancer including patients with axillary node-negative disease

1998 • 56 citations

Invasion and metastasis: the expression and significance of matrix metalloproteinases in carcinomas of the lung.

2001 • 55 citations

Stromelysin-2 overexpression in human esophageal squamous cell carcinoma: potential clinical implications

2002 • 52 citations

Overexpression level of stromelysin 3 is related to the lymph node involvement in non-small cell lung cancer.

2000 • 47 citations

Association of Expression of Metalloproteinases and Their Inhibitors with the Metastatic Potential of Squamous-Cell Lung Carcinomas

1997 • 43 citations

Urokinase Plasminogen Activator as a Predictor of Aggressive Disease in Breast Cancer

1996 • 34 citations