Protein‐kinase‐C inhibitor calphostin C reduces B16 amelanotic melanoma cell adhesion to endothelium and lung colonization

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 21,307 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

CADHERINS: A MOLECULAR FAMILY IMPORTANT IN SELECTIVE CELL-CELL ADHESION

1990 • 1,293 citations

Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C

1989 • 1,126 citations

THE PROTEIN KINASE C FAMILY: HETEROGENEITY AND ITS IMPLICATIONS

1989 • 739 citations

A phorbol ester receptor/protein kinase, nPKC eta, a new member of the protein kinase C family predominantly expressed in lung and skin.

1990 • 434 citations

A derivative of staurosporine (CGP 41 251) shows selectivity for protein kinase C inhibition and In vitro anti‐proliferative as well as In vivo anti‐tumor activity

1989 • 414 citations

Inhibition of protein kinase C by calphostin C is light-dependent

1991 • 374 citations

Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart.

1991 • 212 citations

Selective activation of the γ‐subspecies of protein kinase C from bovine cerebellum by arachidonic acid and its lipoxygenase metabolites

1989 • 188 citations

Bidirectional control of membrane expression and/or activation of the tumor cell IRGpIIb/IIIa receptor and tumor cell adhesion by lipoxygenase products of arachidonic acid and linoleic acid.

1989 • 173 citations

Metastatic tumor cell interactions with endothelium, basement membrane and tissue

1989 • 157 citations

Interactions between cancer cells and the microvasculature: a rate-regulator for metastasis

1989 • 144 citations

Enhanced tumor cell adhesion to the subendothelial matrix resulting from 12(S)‐HETE‐induced endothelial cell retraction

1989 • 122 citations

Lipoxygenase metabolites of arachidonic and linoleic acids modulate the adhesion of tumor cells to endothelium via regulation of protein kinase C.

1991 • 121 citations

Biology of the protein kinase C family

1989 • 120 citations

Tumor promoter-induced membrane-bound protein kinase C regulates hematogenous metastasis.

1988 • 107 citations

Distinct cellular and regional localization of immunoreactive protein kinase C in rat brain.

1987 • 98 citations

The lipoxygenase metabolite 12(S)‐hete induces a cytoskeleton‐dependent increase in surface expression of integrin α_iibβ₃ on melanoma cells

1991 • 97 citations

Inhibition of Invasion of Invasive Human Bladder Carcinoma Cells by Protein Kinase C Inhibitor Staurosporine

1990 • 94 citations

Membrane-associated cathepsin L: A role in metastasis of melanomas

1989 • 84 citations

Effects of 12-O-tetradecanoylphorbol-13-acetate on adhesiveness and lung-colonizing ability of Lewis lung carcinoma cells.

1986 • 63 citations

Increased expression of α_IIb β₃ integrin in subpopulations of murine melanoma cells with high lung‐colonizing ability

1992 • 48 citations

Lipoxygenase Products Regulate IRGpllb/llla Receptor Mediated Adhesion of Tumor Cells to Endothelial Cells, Subendothelial Matrix and Fibronectin

1988 • 47 citations

Cathepsin B to cysteine proteinase inhibitor balance in metastatic cell subpopulations isolated from murine tumors.

1990 • 47 citations

Cytogenetic abnormalities in cancer: with special emphasis on tumor heterogeneity

1990 • 45 citations

Staurosporine: A Prototype of a Novel Class of Inhibitors of Tumor Cell Invasion?

1990 • 43 citations

An in vivo study of the role of the tumor cell cytoskeleton in tumor cell-platelet-endothelial cell interactions.

1990 • 39 citations

Inhibition of protein kinase C arrests proliferation of human tumors

1991 • 24 citations

Separation of High and Low Metastatic Subpopulations from Solid Tumors by Centrifugal Elutriation

1988 • 23 citations

Diacylglycerols and the protein kinase inhibitor H‐7 suppress cell polarity and locomotion of walker 256 carcinosarcoma cells

1989 • 18 citations