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A Single Amino Acid That Determines the Sensitivity of Progesterone Receptors to RU486

Data up to Jan 2025

Published1992
Citations141
References21

Total Citations Per Year

Abstract

References (21)

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

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Cloning of Human Mineralocorticoid Receptor Complementary DNA: Structural and Functional Kinship with the Glucocorticoid Receptor

1987 • 1,920 citations

Primary structure and expression of a functional human glucocorticoid receptor cDNA

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Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B.

1990 • 1,510 citations

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1987 • 1,316 citations

Nuclear receptors enhance our understanding of transcription regulation

1988 • 1,062 citations

Structural analysis of complementary DNA and amino acid sequences of human and rat androgen receptors.

1988 • 530 citations

Contragestion and Other Clinical Applications of RU 486, an Antiprogesterone at the Receptor

1989 • 495 citations

Complete amino acid sequence of the human progesterone receptor deduced from cloned cDNA

1987 • 419 citations

TRANSCRIPTION ACTIVATION BY ESTROGEN AND PROGESTERONE RECEPTORS

1991 • 372 citations

Agonistic and antagonistic activities of RU486 on the functions of the human progesterone receptor.

1990 • 333 citations

Mechanisms of nuclear localization of the progesterone receptor: Evidence for interaction between monomers

1989 • 329 citations

The contribution of the N- and C-terminal regions of steroid receptors to activation of transcription is both receptor and cell-specific

1989 • 299 citations

The chicken progesterone receptor: sequence, expression and functional analysis.

1987 • 236 citations

Cloning and sequence analysis of rabbit progesterone-receptor complementary DNA.

1986 • 204 citations

Human Progesterone Receptor Complexed with the Antagonist RU 486 Binds to Hormone Response Elements in a Structurally Altered Form

1989 • 138 citations

Identification of a functional intermediate in receptor activation in progesterone-dependent cell-free transcription

1990 • 110 citations

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1989 • 86 citations

Screening of anti-progestagens by receptor studies and bioassays

1988 • 45 citations

Hubble's Legacy

1990 • 17 citations

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A Single Amino Acid That Determines the Sensitivity of Progesterone Receptors to RU486 (1992) – Science | Metascience Observatory Explorer