A Kinetic Partitioning Model of Selective Binding of Nonnative Proteins by the Bacterial Chaperone SecB

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Protein Denaturation

1968 • 2,108 citations

A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides

1988 • 1,504 citations

70K heat shock related proteins stimulate protein translocation into microsomes

1988 • 1,276 citations

Specific Intermediates in the Folding Reactions of Small Proteins and the Mechanism of Protein Folding

1982 • 1,041 citations

Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria

1989 • 933 citations

Polypeptide chain binding proteins: Catalysts of protein folding and related processes in cells

1989 • 884 citations

Peptide Binding and Release by Proteins Implicated as Catalysts of Protein Assembly

1989 • 763 citations

GroE heat-shock proteins promote assembly of foreign prokaryotic ribulose bisphosphate carboxylase oligomers in Escherichia coli

1989 • 703 citations

Protein folding in mitochondria requires complex formation with hsp60 and ATP hydrolysis

1989 • 676 citations

The binding cascade of SecB to SecA to SecYE mediates preprotein targeting to the E. coli plasma membrane

1990 • 561 citations

Experimental studies of protein folding and unfolding

1979 • 535 citations

Molecular chaperones: proteins essential for the biogenesis of some macromolecular structures

1989 • 491 citations

Catalysis of protein folding by prolyl isomerase

1987 • 488 citations

Protein disulfide isomerase: Multiple roles in the modification of nascent secretory proteins

1989 • 466 citations

The Sequence of the Amino Acid Residues in Performic Acid-oxidized Ribonuclease

1960 • 428 citations

Transient association of newly synthesized unfolded proteins with the heat-shock GroEL protein

1988 • 388 citations

The antifolding activity of SecB promotes the export of the E. coli maltose-binding protein

1988 • 326 citations

Three pure chaperone proteins of Escherichia coli--SecB, trigger factor and GroEL--form soluble complexes with precursor proteins in vitro.

1989 • 317 citations

Interactions of misfolded influenza virus hemagglutinin with binding protein (BiP).

1989 • 312 citations

Reconstitution of lactic dehydrogenase. Noncovalent aggregation vs. reactivation. 1. Physical properties and kinetics of aggregation

1979 • 282 citations

Sequences of the malE gene and of its product, the maltose-binding protein of Escherichia coli K12.

1984 • 279 citations

Evidence for specificity at an early step in protein export in Escherichia coli

1985 • 272 citations

The Escherichia coli heat shock proteins GroEL and GroES modulate the folding of the beta-lactamase precursor.

1990 • 250 citations

Effects of mutations in heat-shock genes groES and groEL on protein export in Escherichia coli.

1989 • 250 citations

Modulation of Folding Pathways of Exported Proteins by the Leader Sequence

1988 • 243 citations

Purified secB protein of Escherichia coli retards folding and promotes membrane translocation of the maltose-binding protein in vitro.

1988 • 243 citations

Unity in Function in the Absence of Consensus in Sequence: Role of Leader Peptides in Export

1989 • 222 citations

Heavy-chain binding protein recognizes aberrant polypeptides translocated in vitro

1988 • 219 citations

ProOmpA is stabilized for membrane translocation by either purified E. coli trigger factor or canine signal recognition particle

1988 • 196 citations

A quantitative treatment of the kinetics of the folding transition of ribonuclease A

1976 • 167 citations

Physiological role during export for the retardation of folding by the leader peptide of maltose-binding protein.

1989 • 158 citations

Spectrophotometry and spectrofluorimetry : a practical approach

1987 • 144 citations

No Specific Recognition of Leader Peptide by SecB, a Chaperone Involved in Protein Export

1990 • 141 citations

Effects of Escherichia coli secB mutations on pre-maltose binding protein conformation and export kinetics.

1988 • 117 citations

The precursor of beta-lactamase: purification, properties and folding kinetics.

1989 • 110 citations

SecB functions as a cytosolic signal recognition factor for protein export in E. coli

1989 • 107 citations

The mature portion of Escherichia coli maltose-binding protein (MBP) determines the dependence of MBP on SecB for export

1989 • 97 citations

Retardation of folding as a possible means of suppression of a mutation in the leader sequence of an exported protein.

1988 • 95 citations

The Disulfide Linkages in Kallikrein Inactivator of Bovine Lung

1966 • 91 citations

Crystalline α2β2 Complexes of Tryptophan Synthetase of Escherichia coli

1974 • 85 citations

Purification of the Escherichia coli secB gene product and demonstration of its activity in an in vitro protein translocation system

1989 • 84 citations

Cytosolic factor purified from Escherichia coli is necessary and sufficient for the export of a preprotein and is a homotetramer of SecB.

1989 • 83 citations

The Rubisco subunit binding protein

1988 • 71 citations

Characterization of the Escherichia coli protein-export gene secB

1989 • 69 citations

The amino acid sequence of D-ribose-binding protein from Escherichia coli K12.

1983 • 65 citations

Amino Acid Sequences of Fifty Residues from the Amino Termini of the Tryptophan Synthetase α Chains of Several Enterobacteria

1972 • 63 citations

Characterization of an early intermediate in the folding of the .alpha. subunit of tryptophan synthase by hydrogen exchange measurement

1985 • 47 citations

The folding properties of the Escherichia coli maltose-binding protein influence its interaction with SecB in vitro

1990 • 46 citations

Secretion and membrane assembly

1989 • 43 citations