Pre‐ and peri‐natal environmental risks for attention‐deficit hyperactivity disorder (ADHD): the potential role of epigenetic processes in mediating susceptibility

Translating the Histone Code

2001 • 9,488 citations

Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

2003 • 6,017 citations

Epigenetic programming by maternal behavior

2004 • 5,974 citations

The Worldwide Prevalence of ADHD: A Systematic Review and Metaregression Analysis

2007 • 4,813 citations

Epigenetic differences arise during the lifetime of monozygotic twins

2005 • 3,451 citations

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

1998 • 2,686 citations

Cognitive and Behavioral Outcomes of School-Aged Children Who Were Born Preterm

2002 • 2,323 citations

Molecular Genetics of Attention-Deficit/Hyperactivity Disorder

2005 • 2,305 citations

The DNA methyltransferases of mammals

2000 • 1,981 citations

The neurobiological consequences of early stress and childhood maltreatment

2003 • 1,376 citations

In utero programming of chronic disease

1998 • 1,346 citations

Antenatal maternal stress and long‐term effects on child neurodevelopment: how and why?

2007 • 1,303 citations

Inherited epigenetic variation — revisiting soft inheritance

2006 • 1,126 citations

Antenatal maternal anxiety and stress and the neurobehavioural development of the fetus and child: links and possible mechanisms. A review

2004 • 1,064 citations

Maternal antenatal anxiety and children's behavioural/emotional problems at 4 years

2002 • 1,051 citations

Two classes of short interfering RNA in RNA silencing

2002 • 1,022 citations

Maternal Genistein Alters Coat Color and Protects A ^vy Mouse Offspring from Obesity by Modifying the Fetal Epigenome

2006 • 915 citations

Epigenetic Epidemiology of the Developmental Origins Hypothesis

2007 • 833 citations

Vitamin B12, folic acid, and the nervous system

2006 • 785 citations

Maternal Methyl Supplements in Mice Affect Epigenetic Variation and DNA Methylation of Offspring

2002 • 782 citations

Alterations induced by gestational stress in brain morphology and behaviour of the offspring

2001 • 780 citations

Maternal Lifestyle Factors in Pregnancy Risk of Attention Deficit Hyperactivity Disorder and Associated Behaviors: Review of the Current Evidence

2003 • 770 citations

Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood

2006 • 769 citations

The effect of ADHD on the life of an individual, their family, and community from preschool to adult life

2005 • 720 citations

The histone H4 acetyltransferase MOF uses a C₂HC zinc finger for substrate recognition

2001 • 626 citations

Behavioral and Neural Consequences of Prenatal Exposure to Nicotine

2001 • 574 citations

Induction of altered epigenetic regulation of the hepatic glucocorticoid receptor in the offspring of rats fed a protein-restricted diet during pregnancy suggests that reduced DNA methyltransferase-1 expression is involved in impaired DNA methylation and changes in histone modifications

2007 • 561 citations

Developmental Origins of Disease Paradigm: A Mechanistic and Evolutionary Perspective

2004 • 555 citations

Gene–environment correlations: a review of the evidence and implications for prevention of mental illness

2002 • 546 citations

Environmental risk factors for attention‐deficit hyperactivity disorder

2007 • 535 citations

Metastable epialleles in mammals

2002 • 496 citations

Case-Control Study of Attention-Deficit Hyperactivity Disorder and Maternal Smoking, Alcohol Use, and Drug Use During Pregnancy

2002 • 489 citations

Epigenetic gene regulation: Linking early developmental environment to adult disease

2006 • 486 citations

Maternal methyl supplements increase offspring DNA methylation at Axin fused

2006 • 479 citations

Family-Environment Risk Factors for Attention-Deficit Hyperactivity Disorder

1995 • 474 citations

Maternal smoking, drinking or cannabis use during pregnancy and neurobehavioral and cognitive functioning in human offspring

2005 • 458 citations

Attention Deficit and Hyperactivity Disorders in the Offspring of Mothers Exposed to Mild-Moderate Iodine Deficiency: A Possible Novel Iodine Deficiency Disorder in Developed Countries

2004 • 431 citations

Prenatal Exposure to Wartime Famine and Development of Antisocial Personality Disorder in Early Adulthood

1999 • 425 citations

Use and Costs of Medical Care for Children and Adolescents With and Without Attention-Deficit/Hyperactivity Disorder

2001 • 405 citations

A Common Haplotype of the Dopamine Transporter Gene Associated With Attention-Deficit/Hyperactivity Disorder and Interacting With Maternal Use of Alcohol During Pregnancy

2006 • 325 citations

Role of dopamine transporter genotype and maternal prenatal smoking in childhood hyperactive-impulsive, inattentive, and oppositional behaviors

2003 • 295 citations

Molecular studies of major depressive disorder: the epigenetic perspective

2007 • 295 citations

Repeated antenatal corticosteroids: Effects on cerebral palsy and childhood behavior

2004 • 274 citations

Maternal care, the epigenome and phenotypic differences in behavior

2007 • 264 citations

Long-chain polyunsaturated fatty acids in children with attention-deficit hyperactivity disorder

2000 • 226 citations

The origin of schizophrenia: genetic thesis, epigenetic antithesis, and resolving synthesis

2004 • 225 citations

Genomic sequencing reveals a positive correlation between the kinetics of strand-specific DNA demethylation of the overlapping estradiol/glucocorticoid-receptor binding sites and the rate of avian vitellogenin mRNA synthesis.

1986 • 224 citations

Prenatal exposure to polychlorinated biphenyls and attention at school age

2003 • 210 citations

A Folate- and Methyl-Deficient Diet Alters the Expression of DNA Methyltransferases and Methyl CpG Binding Proteins Involved in Epigenetic Gene Silencing in Livers of F344 Rats

2006 • 195 citations

Prenatal Smoking Exposure, Low Birth Weight, and Disruptive Behavior Disorders

2007 • 180 citations

The marks, mechanisms and memory of epigenetic states in mammals

2001 • 167 citations

Fidelity of the Methylation Pattern and Its Variation in the Genome

2003 • 166 citations

Imprinted gene expression in the brain

2005 • 159 citations

Behavioural hyperactivity in rats following postnatal exposure to sub-toxic doses of polychlorinated biphenyl congeners 153 and 126

1998 • 147 citations

Transgenerational Epigenetic Imprinting of the Male Germline by Endocrine Disruptor Exposure during Gonadal Sex Determination

2006 • 147 citations

Consequences of prenatal toxin exposure for mental health in children and adolescents

2007 • 144 citations

Programming of the stress response: a fundamental mechanism underlying the long‐term effects of the fetal environment?

2007 • 141 citations

Longitudinal investigation of task persistence and sustained attention in children with prenatal cocaine exposure

2001 • 139 citations

Evidence for monozygotic twin (MZ) discordance in methylation level at two CpG sites in the promoter region of the catechol‐O‐methyltransferase (COMT) gene

2006 • 136 citations

Neurochemical effects of polychlorinated biphenyls: an overview and identification of research needs.

1997 • 134 citations

Birth Weight and Attention-Deficit/Hyperactivity Symptoms in Childhood and Early Adolescence

2007 • 132 citations

Birthweight and behavioural problems in children: a modifiable effect?

2001 • 131 citations

Allele C‐specific methylation of the 5‐HT2A receptor gene: Evidence for correlation with its expression and expression of DNA methylase DNMT1

2005 • 113 citations

Small body size at birth and behavioural symptoms of ADHD in children aged five to six years

2006 • 112 citations

Prenatal PCB exposure, the corpus callosum, and response inhibition.

2003 • 111 citations

The marks, mechanisms and memory of epigenetic states in mammals

2001 • 102 citations

Attention Problems and Attention-Deficit/Hyperactivity Disorder in Discordant and Concordant Monozygotic Twins: Evidence of Environmental Mediators

2006 • 101 citations

Behavioral Teratogenicity Induced by Nonforced Maternal Nicotine Consumption

2006 • 100 citations

Methylation Dynamics, Epigenetic Fidelity and X Chromosome Structure

2007 • 100 citations

Exposure to Hexachlorobenzene during Pregnancy and Children’s Social Behavior at 4 Years of Age

2006 • 98 citations

HTR2A: Association and expression studies in neuropsychiatric genetics

2005 • 94 citations

Prenatal Alcohol Exposure Causes Attention Deficits in Male Rats.

2005 • 90 citations

Preferential Transmission of Paternal Alleles at Risk Genes in Attention-Deficit/Hyperactivity Disorder

2005 • 83 citations

Folate, DNA stability and colo-rectal neoplasia

2004 • 80 citations

Impact of Prenatal Cocaine Exposure on Attention and Response Inhibition as Assessed by Continuous Performance Tests

2007 • 76 citations

Birth Weight, Stress, and the Metabolic Syndrome in Adult Life

2006 • 66 citations

Sexually dimorphic DNA demethylation in the promoter of the Slp (sex-limited protein) gene in mouse liver.

1995 • 59 citations

Effects of maternal intravenous nicotine administration on locomotor behavior in pre-weanling rats

2006 • 56 citations

Neurodevelopmental and Neurobehavioral Sequelae of Selected Substances of Abuse and Psychiatric Medications in Utero

1999 • 49 citations

Special groups of smokers

2004 • 37 citations

Assessing the risk of fetal alcohol syndrome: understanding substance use among pregnant women

2003 • 37 citations

Dietary influences on cognitive development and behaviour in children

2006 • 35 citations

Dietary influences on cognitive development and behaviour in children

2006 • 32 citations