Characterization of a novel ghrelin cell reporter mouse

Ghrelin is a growth-hormone-releasing acylated peptide from stomach

1999 • 8,261 citations

A Preprandial Rise in Plasma Ghrelin Levels Suggests a Role in Meal Initiation in Humans

2001 • 2,865 citations

Obesity and Metabolic Syndrome in Circadian Clock Mutant Mice

2005 • 2,323 citations

Ghrelin, a Novel Growth Hormone-Releasing Acylated Peptide, Is Synthesized in a Distinct Endocrine Cell Type in the Gastrointestinal Tracts of Rats and Humans¹

2000 • 1,794 citations

The Distribution and Mechanism of Action of Ghrelin in the CNS Demonstrates a Novel Hypothalamic Circuit Regulating Energy Homeostasis

2003 • 1,617 citations

The Tissue Distribution of the mRNA of Ghrelin and Subtypes of Its Receptor, GHS-R, in Humans

2002 • 1,331 citations

A Highly Efficient Escherichia coli-Based Chromosome Engineering System Adapted for Recombinogenic Targeting and Subcloning of BAC DNA

2001 • 1,194 citations

Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin

2001 • 1,181 citations

Identification of the Acyltransferase that Octanoylates Ghrelin, an Appetite-Stimulating Peptide Hormone

2008 • 1,159 citations

Expression of ghrelin receptor mRNA in the rat and the mouse brain

2005 • 1,029 citations

Ghrelin Stimulates Gastric Acid Secretion and Motility in Rats

2000 • 875 citations

Ghrelin controls hippocampal spine synapse density and memory performance

2006 • 806 citations

Ghrelin octanoylation mediated by an orphan lipid transferase

2008 • 789 citations

Mice lacking ghrelin receptors resist the development of diet-induced obesity

2005 • 621 citations

The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress

2008 • 602 citations

Ghrelin Is Present in Pancreatic α-Cells of Humans and Rats and Stimulates Insulin Secretion

2002 • 573 citations

Ghrelin, a Novel Growth Hormone-Releasing Acylated Peptide, Is Synthesized in a Distinct Endocrine Cell Type in the Gastrointestinal Tracts of Rats and Humans

2000 • 469 citations

Distinct pharmacological properties and distribution in neurons and endocrine cells of two isoforms of the human vesicular monoamine transporter.

1996 • 458 citations

Genetic deletion of ghrelin does not decrease food intake but influences metabolic fuel preference

2004 • 455 citations

The ghrelin cell: a novel developmentally regulated islet cell in the human pancreas

2002 • 449 citations

Ghrelin cells replace insulin-producing β cells in two mouse models of pancreas development

2004 • 442 citations

A-like cells in the rat stomach contain ghrelin and do not operate under gastrin control

2001 • 367 citations

A Role of Ghrelin in Neuroendocrine and Behavioral Responses to Stress in Mice

2001 • 357 citations

The Tissue Distribution of the mRNA of Ghrelin and Subtypes of Its Receptor, GHS-R, in Humans

2002 • 356 citations

Expression of Ghrelin and of the GH Secretagogue Receptor by Pancreatic Islet Cells and Related Endocrine Tumors

2002 • 347 citations

Novel Expression and Functional Role of Ghrelin in Rat Testis

2002 • 344 citations

Ablation of ghrelin improves the diabetic but not obese phenotype of ob/ob mice

2006 • 343 citations

Ghrelin-producing cells exist as two types of cells, closed- and opened-type cells, in the rat gastrointestinal tract

2002 • 318 citations

Immunocytochemical observation of ghrelin-containing neurons in the rat arcuate nucleus

2002 • 257 citations

Techniques: Recombinogenic engineering–new options for cloning and manipulating DNA

2001 • 251 citations

Identification and characterization of a novel gastric peptide hormone: The motilin-related peptide

2000 • 233 citations

Characterisation of gastric ghrelin cells in man and other mammals: studies in adult and fetal tissues

2002 • 221 citations

On the Processing of Proghrelin to Ghrelin

2006 • 211 citations

Identification of ghrelin and its receptor in neurons of the rat arcuate nucleus

2004 • 178 citations

Acute psychological stress raises plasma ghrelin in the rat

2006 • 169 citations

Somatostatin suppresses ghrelin secretion from the rat stomach

2003 • 121 citations

Expression of Ghrelin and of the GH Secretagogue Receptor by Pancreatic Islet Cells and Related Endocrine Tumors

2002 • 112 citations

Novel Expression and Functional Role of Ghrelin in Rat Testis

2002 • 105 citations

Vesicular monoamine transporter 2 as a marker of gastric enterochromaffin-like cell tumors

2000 • 80 citations

Secretion of ghrelin from rat stomach ghrelin cells in response to local microinfusion of candidate messenger compounds: A microdialysis study

2007 • 79 citations

Sensory Stimuli Directly Acting at the Central Nervous System Regulate Gastric Ghrelin Secretion. An ex Vivo Organ Culture Study

2007 • 61 citations

Gastric estrogen directly induces ghrelin expression and production in the rat stomach

2006 • 60 citations

Ultrastructure of islet ghrelin cells in the human fetus

2005 • 54 citations

Visualization of ghrelin-producing neurons in the hypothalamic arcuate nucleus using ghrelin-EGFP transgenic mice

2007 • 46 citations

Growth hormone and somatostatin directly inhibit gastric ghrelin secretion. An in vitro organ culture system

2007 • 45 citations

Expression of intrinsic factor and pepsinogen in the rat stomach identifies a subset of parietal cells

1998 • 41 citations

Characterization and species differences in gastric ghrelin cells from mice, rats and hamsters

2004 • 41 citations

Ontogeny of Ghrelin, Obestatin, Preproghrelin, and Prohormone Convertases in Rat Pancreas and Stomach

2008 • 37 citations

Production of bioactive peptides in an in vitro system

2007 • 36 citations

Molecular Characterization of Mouse Gastric Zymogenic Cells

2003 • 34 citations

Stomach-specific Calpain, nCL-2, Localizes in Mucus Cells and Proteolyzes the β-Subunit of Coatomer Complex, β-COP

2006 • 30 citations

Identification and expression of prohormone-converting enzymes in the rat stomach

1996 • 27 citations

Identification and expression of prohormone converting enzymes in the rat stomach

1995 • 14 citations

Immunoreactivity of gastric ECL and A-like cells in fasted and fed rats and mice

2005 • 14 citations